Genes News and Research

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Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

Researchers explored active and passive vaccination among children against respiratory syncytial virus (RSV).

22 Nov 2022

New studies improve understanding of the genetic factors that protect people against COVID-19

Two recent papers by Brazilian researchers have contributed to the scientific understanding of the genetic factors that protect people against infection by SARS-CoV-2 or prevent progression to severe COVID-19.

21 Nov 2022

Gene mutation associated with autism causes an overstimulation of brain cells

Scientists looking to understand the fundamental brain mechanisms of autism spectrum disorder have found that a gene mutation known to be associated with the disorder causes an overstimulation of brain cells far greater than that seen in neuronal cells without the mutation.

21 Nov 2022

Molecular motion of many 'undruggable' proteins reveals previously unseen binding sites

Studying the molecular motion of proteins reveals previously unseen binding sites that could be targeted by new drug candidate molecules.

21 Nov 2022

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

Researchers assessed several approaches for a circulating cell-free deoxyribonucleic acid (cfDNA)-based multi-cancer early detection (MCED) test. Defining the clinical limit of detection (LOD) based on circulating tumor allele fraction (cTAF) enables the comparison of different approaches.

21 Nov 2022

SARS-CoV-2 infection and mRNA vaccination prime transcriptionally distinct CD4+ T cell memory landscapes

Researchers reported that SARS-CoV-2 infection and mRNA vaccination induce distinct memory T cells.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

MIT researchers develop new technique for genome-wide studies of the liver

The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.

21 Nov 2022

Genetic background plays a role in regulating the metabolism of essential polyunsaturated fatty acids

Genetic background has an effect on the metabolism of the essential polyunsaturated fatty acids alpha-linolenic acid and linoleic acid, a recent study from the University of Eastern Finland shows.

21 Nov 2022

Why we should all eat Kimchi and other Korean fermented foods

A recent study reviews various traditional Korean fermented foods for their various health benefits.

20 Nov 2022

Researchers uncover new therapeutic vulnerability in endocrine therapy-resistant breast cancers

For patients with estrogen receptor (ER)-positive breast cancer, development of the so-called Y537S mutation signals that their disease has taken an aggressive course and may become resistant to endocrine therapy.

20 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

New gene classifier can predict the risk of cancer cells recurring or progressing

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2022

Study challenges a long-standing idea about the role of Hippo signaling in organ growth

The Hippo signaling pathway – a genetic program thought to play a central role in organ development – does not instruct normal organ growth in flies and mice, according to a new study.

20 Nov 2022

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

In a recent study published in the journal Cell Reports, researchers in Cincinnati, USA, assessed the impact of dietary alteration to a high-fat diet (HFD) on the intestine.

17 Nov 2022

COVID-19 carries a much higher risk of epilepsy and seizures than influenza

COVID-19 increases risk of both seizures and epilepsy as compared to influenza infection

17 Nov 2022

Mitochondria plays an important role in signal transduction in innate immune pathways

Mitochondria are primarily known as the powerhouse of the cell. However, these cellular organelles are required not only for providing energy: Professor Konstanze Winklhofer and her group at the Faculty of Medicine at Ruhr University Bochum, Germany, recently discovered that mitochondria play an important role in signal transduction in innate immune pathways.

17 Nov 2022

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

Research highlights an understudied aspect of Alzheimer’s disease

Memory loss is often the first sign of Alzheimer's disease, followed by confusion and difficulty thinking. These symptoms reflect the typical pattern of worsening damage to brain tissues. Toxic clusters of proteins first concentrate in the temporal lobes of the brain - the memory area - before spreading to parts of the brain important for thinking and planning.

17 Nov 2022

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

In a recent study posted to the bioRxiv* preprint server, researchers evaluated responses of natural killer (NK) lymphocytes to VACV (vaccinia virus) infections in vivo.

16 Nov 2022

Genes News and Research

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

New studies improve understanding of the genetic factors that protect people against COVID-19

Gene mutation associated with autism causes an overstimulation of brain cells

Molecular motion of many 'undruggable' proteins reveals previously unseen binding sites

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

SARS-CoV-2 infection and mRNA vaccination prime transcriptionally distinct CD4+ T cell memory landscapes

Study suggests bats are an underrecognized arenavirus reservoir

MIT researchers develop new technique for genome-wide studies of the liver

Genetic background plays a role in regulating the metabolism of essential polyunsaturated fatty acids

Why we should all eat Kimchi and other Korean fermented foods

Researchers uncover new therapeutic vulnerability in endocrine therapy-resistant breast cancers

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

New gene classifier can predict the risk of cancer cells recurring or progressing

Study challenges a long-standing idea about the role of Hippo signaling in organ growth

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

COVID-19 carries a much higher risk of epilepsy and seizures than influenza

Mitochondria plays an important role in signal transduction in innate immune pathways

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Research highlights an understudied aspect of Alzheimer’s disease

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

eBook: Using iPSCs models for human disease research and drug discovery eBook

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