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ALKBH7 protein plays key role in controlling programmed necrosis pathway

When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ravaged their DNA.

15 May 2013

Researchers show how cells are driven mainly by water power

Water gives life. Researchers at Linköping University in Sweden now show how the cells in our bodies are driven mainly by water power - a discovery that in the long run opens the way for a new strategy in cancer therapy.

14 May 2013

Nearly 1/10 stroke patients suffer from chronic and debilitating pain

Nearly 1 in 10 stroke patients suffer chronic and debilitating pain, typically described as sharp, stabbing or burning. It's called central poststroke pain syndrome (CPSP). It was first described more than 100 years ago, and it is treatable with medications and magnetic or electrical stimulation of the brain.

9 May 2013

Researchers discover potential treatment for deadly, drug-resistant bacterial infections

Through the serendipity of science, researchers at the University of Pittsburgh have discovered a potential treatment for deadly, drug-resistant bacterial infections that uses the same approach that HIV uses to infect cells.

8 May 2013

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

Adults with end-stage respiratory failure and pulmonary hypertension requiring ECMO (extracorporeal membrane oxygenation) have been "bridged" toward lung transplantation with novel lung assist devices such as the Novalung.

7 May 2013

New gene implicated in Parkinson can delay onset of aging, extend life span

UCLA life scientists have identified a gene previously implicated in Parkinson's disease that can delay the onset of aging and extend the healthy life span of fruit flies. The research, they say, could have important implications for aging and disease in humans.

7 May 2013

Study: Stem cells can communicate with mature heart cells, form electrical couplings

Stem cells drawn from amniotic fluid show promise for tissue engineering, but it's important to know what they can and cannot do. A new study by researchers at Rice University and Texas Children's Hospital has shown that these stem cells can communicate with mature heart cells and form electrical couplings with each other similar to those found in heart tissue.

3 May 2013

Preclinical data of Emergent BioSolutions' ES414 in mCRPC presented at PEGS 2013

Emergent BioSolutions Inc. today announced that it presented preclinical data on its lead bispecific ADAPTIRTM (Modular Protein Technology) molecule, ES414, at the 9th Annual Protein and Antibody Engineering Summit, currently underway in Boston, MA.

3 May 2013

Study results support new view of molecules important for nerve cell signaling

National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages.

3 May 2013

New hope for patients with myotonic dystrophy

There's hope for patients with myotonic dystrophy. A new small molecule developed by researchers at the University of Illinois has been shown to break up the protein-RNA clusters that cause the disease in living human cells, an important first step toward developing a pharmaceutical treatment for the as-yet untreatable disease.

2 May 2013

Study may pave way for new strategies to fight cancer cells

For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells.

29 Apr 2013

Researchers discover new insights into how cells make transition from nonmalignant to metastatic

Cancer cells that can break out of a tumor and invade other organs are more aggressive and nimble than nonmalignant cells, according to a new multi-institutional nationwide study.

29 Apr 2013

Antihistamine drugs work by preventing histamine from attaching to H1 receptors

Itchy eyes, scratchy throat, running nose--it's allergy season! What triggers these allergic reactions, and how do allergy medications work?

26 Apr 2013

Research on miRNAs offers new therapeutic potential to fight diseases

RNA molecules, made from DNA, are best known for their role in protein production. MicroRNAs (miRNAs), however, are short (~22) nucleotide RNA sequences found in plants and animals that do not encode proteins but act in gene regulation and, in the process, impact almost all biological processes - from development to physiology to stress response.

26 Apr 2013

Cell sorting device improves detection of circulating tumor cells

An automated cell sorting device developed in the USA may allow circulating tumor cells to be detected with greater accuracy than by current methods, say researchers.

25 Apr 2013

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn’t. In the journal Angewandte Chemie, a British team has now introduced a new method that makes it possible to enrich the rare gene segments that contain the modified base hydroxymethylcytosine and to identify individual hydroxymethylcytosine molecules in DNA. Such modifications are associated with autoimmune diseases and cancer.

24 Apr 2013

Membrane News and Research

ALKBH7 protein plays key role in controlling programmed necrosis pathway

Researchers show how cells are driven mainly by water power

Nearly 1/10 stroke patients suffer from chronic and debilitating pain

Researchers discover potential treatment for deadly, drug-resistant bacterial infections

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

New gene implicated in Parkinson can delay onset of aging, extend life span

Study: Stem cells can communicate with mature heart cells, form electrical couplings

Preclinical data of Emergent BioSolutions' ES414 in mCRPC presented at PEGS 2013

Study results support new view of molecules important for nerve cell signaling

New hope for patients with myotonic dystrophy

Study may pave way for new strategies to fight cancer cells

Researchers discover new insights into how cells make transition from nonmalignant to metastatic

Antihistamine drugs work by preventing histamine from attaching to H1 receptors

Research on miRNAs offers new therapeutic potential to fight diseases

Cell sorting device improves detection of circulating tumor cells

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Researchers studying lipids to learn more about normal, abnormal biology

Palliative radiotherapy for bone metastases can improve quality of life in elderly patients

Researchers explore new technique to determine the activity of different calcium channels in cancer cells

TSRI scientists find way to directly turn bone marrow stem cells into brain cells

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo