Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Hedgehog and mTOR pathway are active in esophageal cancer

Identification of a non-traditional pathway for spiriting a cancer-promoting protein into the cell nucleus points to a possible combination therapy for esophageal cancer and indicates a mechanism of resistance for new drugs that attack the Hedgehog pathway.

20 Mar 2012

Circadian rhythms control production of metabolites

By analyzing the hundreds of metabolic products present in the liver, researchers with the UC Irvine Center for Epigenetics & Metabolism have discovered that circadian rhythms - our own body clock - greatly control the production of such key building blocks as amino acids, carbohydrates and lipids.

20 Mar 2012

iPSYCH project to study five specific mental disorders

Is it possible to prevent the development of schizophrenia? Can certain patients develop autism if they carry a specific gene and have been exposed to a viral fetal infection? Should all ADHD patients take the same type of medication? This unique research project will try to answer these questions. The project is based at Aarhus University and will be known as 'The Lundbeck Foundation's Initiative for Integrative Psychiatric Research.'

20 Mar 2012

Single dose of X-ray radiation can prevent glaucoma

Jackson Laboratory researchers have demonstrated that a single, targeted x-ray treatment of an individual eye in young, glaucoma-prone mice provided that eye with apparently life-long and typically complete protection from glaucoma.

20 Mar 2012

Ingenuity Variant Analysis and iReport selected for Weill Cornell sequencing core facility

Ingenuity Systems, a leading provider of information and analysis solutions for life science researchers, today announced that the Weill Cornell Medical College has chosen Ingenuity Variant Analysis and Ingenuity iReport for use in its sequencing core facility.

19 Mar 2012

Study of genes may hold the key to improved skin care

Ever wonder why two people who are the same age may look years apart? While extrinsic factors such as sun exposure and smoking can contribute to skin aging, intrinsic factors - namely the genes inherited from our parents - can have an even greater influence on how our skin ages.

17 Mar 2012

Deletion of Hms1 protein inhibits Candida albicans infection

Scientists at the University of Toronto have found a molecular mechanism that plays a key role in the transition of Candida albicans yeast into disease-causing fungus-one of the leading causes of hospital-acquired infection.

17 Mar 2012

Novel sensor selectively screens single molecules passing through nanopores

A novel type of sensor, based on nanometer-scale pores in a semiconductor membrane, is a step closer to practical use in applications such as analyzing the protein contents of a single cell. Researchers pioneering single-molecule nanopore sensor technology at the Technische Universit-t M-nchen (TUM) have shown its potential through a succession of experiments over the past few years.

16 Mar 2012

Study identifies 190 proteins crucial to the functions of key immune sensors

In a healthy immune system, invading pathogens trigger a cascade of alerts and responses to fight off the infection. Sensors called toll-like receptors, or TLRs, act as one of the first lines of defense. Two of these sensors, known as TLR7 and TLR9, specifically recognize and respond to microbial RNA and DNA, respectively. But what determines how these TLRs get where they need to be and sound the alarm for pathogen infection?

15 Mar 2012

Anti-inflammatory drugs may offer novel treatment for CHD

A large international study indicates that anti-inflammatory drugs may become a new tool for preventing and treating coronary heart disease (CHD), the leading global cause of death.

15 Mar 2012

Scientists track genetic pathway of prostate cancer in new approach to drug discovery

Tracking the genetic pathway of a disease offers a powerful, new approach to drug discovery, according to scientists at the University of California, San Diego School of Medicine who used the approach to uncover a potential treatment for prostate cancer, using a drug currently marketed for congestive heart failure. Their findings are published in the current online issue of the Proceedings of the National Academy of Sciences.

14 Mar 2012

Reviva to initiate enrollment in RP503 phase 2 study for schizophrenia

Reviva Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced enrollment of patients in its phase 2 clinical study of RP503 for schizophrenia and schizoaffective disorder.

13 Mar 2012

TGen to present new research about multiple myeloma at AzMN conference

The Translational Genomics Research Institute (TGen) will present new research about the blood-cell cancer known as multiple myeloma at a free public conference hosted by the Arizona Myeloma Network.

12 Mar 2012

Salt resistant wheat developed using genomics

Matthew Gilliham, of the University of Adelaide, said the new variety of durum wheat would be made freely available to publicly funded breeding programs overseas. Field trials in Moree and at other sites across southern Australia have shown that the new variety has a grain yield in salty soil of up to 25 per cent higher than that of the standard variety.

12 Mar 2012

Tumors can be more complex than imagined earlier: Study

Researchers speculate that cancers may be more complex that they knew. And that's why a single tissue sample taken from a single tumor may not be the best way to figure out a course of treatment they claim.

11 Mar 2012

First ever analysis of genetic variation between different regions of same tumour

Taking a sample from just one part of a tumour may not give a full picture of its 'genetic landscape', according to a landmark study published in the New England Journal of Medicine.

8 Mar 2012

NCGR to host eighth annual NMBIST symposium on March 22-23, 2012

The National Center for Genome Resources (NCGR) announced today that it will host the eighth annual New Mexico Bioinformatics, Science and Technology (NMBIST) symposium on March 22-23, 2012.

7 Mar 2012

Illumina launches new highly multiplexed cancer panel

Illumina today introduced the TruSeq Amplicon - Cancer Panel, a highly multiplexed panel that will allow researchers to accurately sequence hundreds of the most relevant cancer loci, even in difficult samples such as formalin-fixed, paraffin embedded (FFPE) tumor samples.

From Illumina, Inc. 7 Mar 2012

PGen study to examine impact of consumer genomics

As genetic risk information plays an increasingly important role in the diagnosis and treatment of many diseases, private companies have made personal genomic testing for these risk factors widely available to the public. However, very little data has been gathered to understand the motivations and expectations of consumers of personal genomic services, the psychological and behavioral impact of these services, and the associated ethical, legal and social issues-until now.

5 Mar 2012

New APS policy requires reporting of sex and gender in experimental studies

The American Physiology Society (APS) has announced a new policy requiring the reporting of the sex of experimental animals and the sex or gender of humans used in studies submitted for publication in any of the organization's 13 peer-reviewed journals.

3 Mar 2012