Laboratory News and Research

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New way to carry drugs across the blood-brain barrier using nanoparticles

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Former players’ cognitive performance associated with concussion symptoms during football careers

Former professional football players who reported experiencing concussion symptoms during their playing careers were found to perform worse on a battery of cognitive tests than non-players, according to a study led by Mass General Brigham investigators from McLean Hospital and Spaulding Rehabilitation Network.

3 Mar 2023

Deep learning–based method can accurately detect Alzheimer’s disease based on data from brain MRIs

Although investigators have made strides in detecting signs of Alzheimer's disease using high-quality brain imaging tests collected as part of research studies, a team at Massachusetts General Hospital (MGH) recently developed an accurate method for detection that relies on routinely collected clinical brain images.

3 Mar 2023

Study estimates and compares excess mortality due to cardiovascular diseases across multiple pandemic waves in the US

Researchers estimated excess cardiovascular deaths in the USA between March 2020 and March 2022.

3 Mar 2023

Festo breaks price/performance barriers with new multi-axis gantry

Festo introduces the EXCL, a multi-axis gantry kit that lowers acquisition, engineering, and assembly costs for automated sample handling and liquid dispensing in laboratory devices.

From Festo Ltd. 2 Mar 2023

Serious pneumococcal infection increases the risk of a heart attack significantly

After the onset of serious pneumococcal infections, patients are at a significantly increased risk of having a heart attack, according to a Vanderbilt study published in the journal Clinical Infectious Diseases.

2 Mar 2023

Neural underpinnings of atypical visual sensory behaviors in some children with autism

There is this picture – you may have seen it. It is black and white and has two silhouettes facing one another. Or maybe you see the black vase with a white background. But now, you likely see both.

2 Mar 2023

New delivery system based on lipid nanoparticles could increase the efficiency of gene therapy

Lipid nanoparticles have been used to encapsulate CRISPR-Cas9 and deliver it to cells in mice, where it was highly effective at knocking down expression of a target protein.

2 Mar 2023

Wastewater-based monitoring is effective in detecting viral outbreaks in schools

Schools are among the most notable settings people associate with picking up viral infections such as the common cold, various types of the flu or other respiratory viruses.

2 Mar 2023

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Researchers assessed the role of renalase as an independent predictor of COVID-19-related mortality.

2 Mar 2023

Using a mathematical model for future pandemic preparedness

Scientists have developed mathematical models that analyze the data obtained from an initial wave of the influenza pandemic to predict the dynamics of subsequent waves. Such predictions could be useful for pandemic preparedness.

2 Mar 2023

Modifying gut flora before surgery could reduce postoperative complications in colorectal cancer patients

In a promising study, Canadian researchers have shown for the first time in mice that modifying intestinal flora before surgery could reduce postoperative complications in colorectal cancer patients.

1 Mar 2023

Using vitamin B5 supplementation to boost red blood cell production in people with myelodysplastic syndromes

Scientists from Barts Cancer Institute at Queen Mary University of London and the Francis Crick Institute, have uncovered why patients with a rare type of blood cancer suffer from ineffective red blood cell production, and how vitamin B5 could be combined with existing drugs to improve outcomes.

1 Mar 2023

Newly discovered mechanism likely contributes to the severity of P. aeruginosa infections

Bacteria of the species Pseudomonas aeruginosa are antibiotic-resistant hospital germs that can enter blood, lungs and other tissues through wounds and cause life-threatening infections.

1 Mar 2023

Breaking apart certain proteins may offer a pathway to treat Alzheimer's diease

Certain diseases, including Alzheimer's, are currently considered "undruggable" because traditional small molecule drugs can't interfere with the proteins responsible for the illnesses.

1 Mar 2023

New screening tool can efficiently assess cognition issues in older adults

A self-administered screening tool, developed by Cleveland Clinic researchers, can effectively and efficiently assess cognition issues in older adults.

1 Mar 2023

Antiverse raises funding and demonstrates therapeutic antibody identification with AI-driven drug discovery platform

Antiverse Ltd (Antiverse), a biotechnology company developing a computational antibody drug discovery platform, today announced the successful identification of functional antibody clusters targeting two G-protein-coupled receptors (GPCRs), both displaying versatile binding profiles and nanomolar affinity.

From Antiverse 1 Mar 2023

Covid-19 vaccination can curb the effect of long COVID on patients' social, professional, and family lives

Vaccination against SARS-CoV-2, the virus responsible for COVID-19, may lessen the severity and duration of 'long COVID' in those with persistent symptoms after infection, suggests a study that closely imitates a randomized clinical trial, and published in the open access journal, BMJ Medicine.

1 Mar 2023

Product development and drug delivery at Seda

In this interview, NewsMedical speaks with Shanoo about her career progression and role in Seda Pharmaceutical regarding product development and drug delivery. She also outlines some of the services that Seda offers.

From Seda Pharmaceutical Development Services 1 Mar 2023

PARK2 duplication or microdeletion and neurological diseases

In a recent study published in the Genes journal, researchers assessed the impact of PARK2 duplication or microdeletion on neurological diseases such as Parkinson's.

28 Feb 2023

Laboratory News and Research

New way to carry drugs across the blood-brain barrier using nanoparticles

Former players’ cognitive performance associated with concussion symptoms during football careers

Deep learning–based method can accurately detect Alzheimer’s disease based on data from brain MRIs

Study estimates and compares excess mortality due to cardiovascular diseases across multiple pandemic waves in the US

Festo breaks price/performance barriers with new multi-axis gantry

Serious pneumococcal infection increases the risk of a heart attack significantly

Neural underpinnings of atypical visual sensory behaviors in some children with autism

New delivery system based on lipid nanoparticles could increase the efficiency of gene therapy

Wastewater-based monitoring is effective in detecting viral outbreaks in schools

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Using a mathematical model for future pandemic preparedness

Modifying gut flora before surgery could reduce postoperative complications in colorectal cancer patients

Using vitamin B5 supplementation to boost red blood cell production in people with myelodysplastic syndromes

Newly discovered mechanism likely contributes to the severity of P. aeruginosa infections

Breaking apart certain proteins may offer a pathway to treat Alzheimer's diease

New screening tool can efficiently assess cognition issues in older adults

Antiverse raises funding and demonstrates therapeutic antibody identification with AI-driven drug discovery platform

Covid-19 vaccination can curb the effect of long COVID on patients' social, professional, and family lives

Product development and drug delivery at Seda

PARK2 duplication or microdeletion and neurological diseases

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