immunity News and Research

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Previous SARS-CoV-2 infection may negate need for two vaccine doses

Researchers in the United States have shown that two doses of vaccine may not be necessary to protect against coronavirus disease 2019 (COVID-19) among people who have already been infected with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Feb 2021

Pfizer-BioNTech vaccine shows promise against new SARS-CoV-2 variants

A team of researchers in the U.S. studied the Pfizer-BioNTech vaccine candidate - currently being rolled out in many parts of the world to high-risk individuals - to see if it still holds up against mutant strains of the virus and yielded encouraging results.

2 Feb 2021

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

Researchers have explored heritable factors, age and body mass on temperature variation between humans. One notable finding is that the current threshold for detecting fever in older adults may be too high, precluding the ability to detect COVID-19 early on

2 Feb 2021

ZyCoV-D DNA vaccine immunogenic against SARS-CoV-2 in animal models

In the absence of effective therapeutics or preventives, vaccines have become the focus of attention. Though over 170 vaccines are in preclinical and about 60 in clinical development, very few are based on plasmid DNA technology. However, a new preprint research paper posted to the bioRxiv* server reports the immunogenicity of a DNA vaccine candidate.

2 Feb 2021

Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2

Among the hundred million or so cases of coronavirus disease 2019 (COVID-19) that have occurred since the pandemic began, pregnant women have been a conspicuous risk group. However, the exact nature of the risk they and their fetuses face, and the mechanism by which it operates, is far from clear.

2 Feb 2021

By July of 2020, 16.8 million people in the US infected with SARS-CoV-2 and didn’t know it

A seroprevalence study of nearly 10,000 people in the United States in the first six months of the COVID-19 pandemic suggests there were at least five people with undiagnosed disease for every case diagnosed.

1 Feb 2021

Early induction of functional SARS-CoV-2-specific T cells linked with mild symptoms in COVID-19 patients

Humoral and cellular adaptive immunity are two immune mechanisms that act against pathogens. Humoral immunity is mediated by antibodies, while cellular immunity does not involve antibodies and is, instead, facilitated by T cells.

1 Feb 2021

Life-threatening genetic immunodeficiency reversed by a rare DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

1 Feb 2021

When your chance for a covid shot comes, don’t worry about the numbers

When getting vaccinated against covid-19, there's no sense being picky. You should take the first authorized vaccine that's offered, experts say.

1 Feb 2021

Researchers in Japan compare two seroprevalence antibody tests for SARS-CoV-2

Researchers have shown that using reliable antibody tests in conjunction is an effective way to estimate seroprevalence in low prevalence settings.

1 Feb 2021

Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

Now, a new preprint research paper describes a chimpanzee adenovirus-vectored vaccine that, when administered intranasally in rhesus macaques, led to a robust immune response and demonstrated protection against infection by the virus that causes COVID-19, namely, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The preprint is published on the bioRxiv server.

1 Feb 2021

SARS-CoV-2-specific T cells are key players in decreasing COVID-19 mortality

A recent US study, currently available on medRxiv preprint server, supports a beneficial rather than immunopathologic role for effector T-cells during serious infections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) –

31 Jan 2021

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in coronavirus disease 2019 (COVID-19).

31 Jan 2021

Research identifies and explores the impacts of emergent COVID-19 behavioral identities

New research by Mimi E. Lam (University of Bergen) just published in Humanities and Social Sciences Communications identifies and explores the impacts of salient viral or COVID-19 behavioural identities that are emerging.

30 Jan 2021

Survey: More than a third of Americans either unlikely or unsure to get a COVID-19 vaccine

News reports indicate COVID-19 vaccines are not getting out soon enough nor in adequate supplies to most regions, but there may be a larger underlying problem than shortages. A University of California, Davis, study found that more than a third of people nationwide are either unlikely or at least hesitant to get a COVID-19 vaccine when it becomes available to them.

30 Jan 2021

New forecasts show possibility of spike in COVID-19 cases and deaths in the spring

The latest COVID-19 forecasts from the Institute for Health Metrics and Evaluation at the University of Washington now incorporate two new virus variants.

29 Jan 2021

Salk's NOMIS Center receives $9.5 million to grow and expand in health, immunity research

As we endure a global viral pandemic, our appreciation for health and immunity has never been greater. Now, thanks to a generous gift from the NOMIS Foundation, Salk's NOMIS Center for Immunobiology and Microbial Pathogenesis will receive $9.5 million to grow and expand, while continuing to be a leader in health and immunity research.

29 Jan 2021

Researchers explore adaptive immunity against human coronaviruses

A recent study shows that long-term adaptive immunity to endemic coronaviruses is widespread, but low in magnitude, and that it shares phenotypic features of spike-specific antibodies and T cell memory across all tested coronaviruses.

29 Jan 2021

What are the main drivers of COVID-19 vaccine hesitancy?

A study conducted in the UK has examined attitudes towards vaccination protecting against COVID-19 and highlighted some of the main drivers of willingness or unwillingness to be immunized.

29 Jan 2021

U.S. public divided over COVID-19 “immunity passports” idea

A nationally representative survey conducted in the U.S. suggests that the public is fairly evenly divided in its support of immunity certificates or “passports” to enable the selective lifting of restrictions placed on people during the COVID-19 pandemic.

29 Jan 2021

immunity News and Research

Previous SARS-CoV-2 infection may negate need for two vaccine doses

Pfizer-BioNTech vaccine shows promise against new SARS-CoV-2 variants

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

ZyCoV-D DNA vaccine immunogenic against SARS-CoV-2 in animal models

Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2

By July of 2020, 16.8 million people in the US infected with SARS-CoV-2 and didn’t know it

Early induction of functional SARS-CoV-2-specific T cells linked with mild symptoms in COVID-19 patients

Life-threatening genetic immunodeficiency reversed by a rare DNA change

When your chance for a covid shot comes, don’t worry about the numbers

Researchers in Japan compare two seroprevalence antibody tests for SARS-CoV-2

Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

SARS-CoV-2-specific T cells are key players in decreasing COVID-19 mortality

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Research identifies and explores the impacts of emergent COVID-19 behavioral identities

Survey: More than a third of Americans either unlikely or unsure to get a COVID-19 vaccine

New forecasts show possibility of spike in COVID-19 cases and deaths in the spring

Salk's NOMIS Center receives $9.5 million to grow and expand in health, immunity research

Researchers explore adaptive immunity against human coronaviruses

What are the main drivers of COVID-19 vaccine hesitancy?

U.S. public divided over COVID-19 “immunity passports” idea

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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