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Etoricoxib better than opioid drug tramadol for postoperative pain: Study

For patients with moderate pain after foot surgery, the cyclo-oxygenase 2 (COX-2) inhibitor drug etoricoxib provides better pain relief with fewer side effects than the opioid drug tramadol, concludes a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

3 Aug 2010

New fat cell with potentially harmful characteristics: Study

The new fat cells arise from stem cells in the bone marrow that travel through the blood stream to fat tissue. They are termed bone marrow progenitor-derived adipocytes. The discovery also revealed that male and female subjects accumulate the new fat cells differently. The research also may help to explain the link between types of obesity and heart disease and other illnesses.

3 Aug 2010

BioMarin provides update on PEG-PAL Phase 2 clinical study for phenylketonuria

BioMarin Pharmaceutical Inc. announced today an update in the Phase 2 clinical study of PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase) for the treatment of phenylketonuria (PKU). Data reported in this announcement reflect preliminary results as of July 23, 2010. Complete top-line results are expected in the fourth quarter of 2010.

3 Aug 2010

BioMarin reports $0.5 million GAAP net loss for second-quarter 2010

BioMarin Pharmaceutical Inc. today announced financial results for the second quarter of 2010. GAAP net loss was $0.5 million ($0.01 per diluted share) for the second quarter of 2010, compared to GAAP net income of $1.3 million ($0.01 per diluted share) for the second quarter of 2009. Non-GAAP net income was $8.6 million ($0.08 per diluted share) for the second quarter of 2010, compared to non-GAAP net income of $9.0 million ($0.09 per diluted share) for the second quarter of 2009.

3 Aug 2010

Color red makes men more alluring to women: Study

It's a symbol of courage and sacrifice, of sin and sexuality, of power and passion - and now new research demonstrates that the color red makes men more alluring to women.In the United States, England, Germany and China, women found men more appealing when they were either pictured wearing red or framed in red, compared with other colors. The finding is reported in the August issue of the Journal of Experimental Psychology: General, published by the American Psychological Association.

3 Aug 2010

Researchers develop techniques to identify evolution of drug resistance strains of malaria

Researchers at Case Western Reserve University developed techniques to quickly identify evolution of drug resistance in strains of malaria. Their goal is to enable the medical community to react quickly to inevitable resistance and thereby save lives while increasing the lifespan of drugs used against the disease.Currently, disease monitoring requires months of clinical trials. The new methods can provide more information in just days, and far cheaper.

3 Aug 2010

High levels of lead found in Mount Isa children: Study

According to a report published in the Medical Journal of Australia (MJA) yesterday, on average one child in the Queensland mining town of Mount Isa will exceed safe lead levels every nine days. The report also claimed that not enough was done to address the problem. MP Betty Kiernan has defended the measures taken to address this serious problem.

3 Aug 2010

Hospitals seek new ways to streamline care

News outlets report on hospital issues, including the differences between for-profit and nonprofit hospitals and efforts to streamline care.

2 Aug 2010

Research findings could lead to new drugs that reduce severity of blood infections leading to sepsis

Scientists have made an important discovery that could lead to new drugs that reduce the severity of blood infections leading to sepsis. Research presented in the August 2010 issue of Journal of Leukocyte Biology shows how interfering with the function of the cell membrane protein called "Programmed Death 1" (PD-1) improves survival in a clinically relevant model of severe infection.

2 Aug 2010

WellDoc DiabetesManager System receives FDA clearance

WellDoc, a healthcare company that develops technology solutions to improve chronic disease management outcomes and reduce healthcare costs, today announced that it has received United States Food and Drug Administration 510(k) clearance to market the WellDoc DiabetesManager System to healthcare providers and their adult patients with type 2 diabetes.

2 Aug 2010

Cardioxyl Pharmaceuticals achieves positive results in first clinical study of CXL-1020 for ADHF

Cardioxyl Pharmaceuticals, Inc., a clinical-stage pharmaceutical company developing novel therapeutic agents for the treatment of cardiovascular disease, today announced that it has achieved positive safety and tolerability results in the first clinical study of its lead drug candidate, CXL-1020, for the treatment of patients with acute decompensated heart failure. Each year in the United States, more than one million patients are hospitalized with acute heart failure.

2 Aug 2010

First Edition: August 2, 2010

Today's headlines include news about a pre-recess Senate push to pass a state aid measure as well as a preview of a White House report to be issued today that predicts savings in the Medicare program.

2 Aug 2010

Research shows no link between CCSVI and development of multiple sclerosis

Two important new studies challenge the controversial hypothesis that venous congestion—chronic cerebrospinal venous insufficiency (CCSVI)—contributes to the development of multiple sclerosis (MS). This theory has resulted in many MS patients receiving experimental endovascular angioplasty, a treatment for MS unproven by clinical trials.

2 Aug 2010

Scientists identify way to regulate uncontrolled growth of blood vessels

Researchers at the University of California, San Diego School of Medicine have identified a new way to regulate the uncontrolled growth of blood vessels, a major problem in a broad range of diseases and conditions.

2 Aug 2010

microRNA protects red blood cells from oxidant stress: Study

Pediatric researchers have discovered a new biological pathway in which small segments of RNA, called microRNA, help protect red blood cells from injury caused by chemicals called free radicals. The microRNA seems to have only a modest role when red blood cells experience normal conditions, but steps into action when the cells are threatened by oxidant stress.

2 Aug 2010

Abnormal sleep duration adversely affects cardiovascular health

A study in the Aug. 1 issue of the journal Sleep suggests that regularly sleeping for more or less than seven hours per day is associated with an increased risk of cardiovascular disease.

2 Aug 2010

Researchers create artificial RNA inhibitor to block excess blood cells formation

Researchers at UT Southwestern Medical Center have uncovered a key step in the creation of new red blood cells in an animal study.They found that a tiny fragment of ribonucleic acid (RNA), a chemical cousin of DNA, prompts stem cells to mature into red blood cells. The researchers also created an artificial RNA inhibitor to block this process.

2 Aug 2010

Body’s natural cell suicide program may trigger tumor development: Study

Cancer research springs a surprise. Researchers at Walter and Eliza Hall Institute in Melbourne have found that programmed cell death (apoptosis) or cell suicide plays a role in tumor development. This process is an important phenomenon in our body as it helps remove damaged cells. Now apoptosis has been found to be protective against cancer formation and autoimmune diseases.

1 Aug 2010

Research findings point to new ways to improve quality of future trials through better training

Practitioners of clinical medicine are familiar with learning curves, and strategies like simulation are increasingly used to minimize learning-curve effects on clinical care. Because similar learning curves have been hinted at in some clinical trials, researchers at Duke University Medical Center studied the phenomenon in the data record of a large, multi-site clinical trial. Their findings point to ways to improve the quality of future trials through better training and simulation exercises.

31 Jul 2010

Taoist Tai Chi internal arts of health celebrates 40 years

Dimitri Granovski, a Russian immigrant to Canada, says that after 20 years of chronic migraines, he's become painkiller-free by practising these arts for only three months. Samantha Albert of Stratford, Ontario, says they help her deal with the effects of a critical blood disorder called amyloidosis. Helen Gaunt a wine producer in Margaret River, Australia, attributes her smooth recovery from thyroid and breast cancer to their practice.

31 Jul 2010