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Gut bacteria composition could predict toxicity of chemotherapy drugs in cancer patients

Albert Einstein College of Medicine researchers report that the composition of people's gut bacteria may explain why some of them suffer life-threatening reactions after taking a key drug for treating metastatic colorectal cancer.

1 Nov 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Sartorius 16 Oct 2017

CUMC researchers discover ‘cell of origin’ for esophageal cancer

Columbia University Medical Center researchers have identified cells in the upper digestive tract that can give rise to Barrett's esophagus, a precursor to esophageal cancer. The discovery of this "cell of origin" promises to accelerate the development of more precise screening tools and therapies for Barrett's esophagus and esophageal adenocarcinoma, the fastest growing form of cancer in the U.S.

11 Oct 2017

Scientists use BR nanoparticles to develop photoacoustic imaging and photothermal cancer therapy

Sangyong Jon, a professor in the Department of Biological Sciences at KAIST, and his team developed combined photoacoustic imaging and photothermal therapy for cancer by using Bilirubin (BR) nanoparticles.

26 Sep 2017

FDA approves scope with disposable part aimed at reducing superbug infections

Seeking to prevent superbug outbreaks, federal health officials said they have approved the first gastrointestinal medical scope with a disposable cap for use in the U.S.

22 Sep 2017

First duodenoscope with disposable distal cap approved by FDA

The U.S. Food and Drug Administration today cleared the first duodenoscope with a disposable distal cap, a new feature that will improve access for cleaning and reprocessing.

20 Sep 2017

Researchers decipher how some Listeria strains survive high food hygiene standards

Listeria monocytogenes is a foodborne pathogen that colonizes and reproduces on diverse food products including cheese or meat.

30 Aug 2017

Researchers provide approaches to optimize cardiovascular risk reduction for patients with SAMS

Statins are highly effective for preventing heart attacks by reducing low-density lipoprotein or "bad" cholesterol.

29 Aug 2017

Blood cleaning device can also effectively provide a bridge to liver transplantation

Severe acute liver failure (ALF), a rare but life-threatening illness, is associated with high death rates if patients don't receive timely treatment or a liver transplant.

23 Aug 2017

Natural ways to support a healthy liver

Summer is here and with it comes the potential for fun, frolics and a little more alcohol than usual. Whether it’s festival beers, holiday cocktails or a few too many Pimms’ at the family BBQ, with increased alcohol consumption comes an increased workload for your liver.

From BetterYou Ltd 16 Aug 2017

Nutrition researchers outline cardiometabolic benefits of plant-based eating patterns

Plant-based eating patterns continue to soar in popularity and a group of nutrition researchers outlines the science behind this sustainable trend in a review paper, entitled "Cardiometabolic benefits of plant-based diets," which appears as an online advance in the Aug. 9, 2017, edition of Nutrients.

11 Aug 2017

Negocios Now names Loyola Medicine neurologist among 50 most influential Latinos in Chicago

Loyola Medicine neurologist José Biller, MD, has been named to Negocios Now's list of the 50 Most Influential Latinos in the Chicago Area.

2 Aug 2017

Scope maker Olympus hit with $6.6 million verdict in superbug outbreak case

A jury ordered the giant medical scope maker Olympus Corp. to pay a Seattle hospital $6.6 million in damages tied to a deadly superbug outbreak — and told the hospital to pay $1 million to a deceased patient's family.

25 Jul 2017

Scientists reveal key role of excess gut calcium in C. diff infections

It lurks in hospitals and nursing homes, surviving the cleaning crew's attempt to kill it by holing up in a tiny hard shell. It preys upon patients already weak from disease or advanced age.

13 Jul 2017

New study links hepatic inflammation to western diet

A new study in The American Journal of Pathology reports that mice fed a Western diet, which is high in fat and sugar, resulted in hepatic inflammation, especially in males. Moreover, liver inflammation was most pronounced in Western diet-fed male mice that also lacked farnesoid x receptor (FXR), a bile acid receptor.

12 Jul 2017

Cambridge scientists develop new method for growing and transplanting artificial bile ducts

Cambridge scientists have developed a new method for growing and transplanting artificial bile ducts that could in future be used to help treat liver disease in children, reducing the need for liver transplantation.

3 Jul 2017

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

A multi-disciplinary team of researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, the Institute of Bioengineering and Nanotechnology of A*STAR, and BioSyM, Singapore-MIT Alliance for Research and Technology have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.

30 Jun 2017

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab.

9 Jun 2017

Genetic sequencing could help direct treatment for 72% of advanced cancer patients

A new analysis finds that nearly three-quarters of 500 patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor's genetic landscape.

2 Jun 2017

MGH scientists show how Shigella survives journey from mouth to the colon

Surviving the treacherous journey through the human body from the mouth to the colon takes a special kind of bacterial pathogen.

31 May 2017