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Researchers discover new gene associated with aortic aneurysms

An interdisciplinary team of researchers has identified a new gene linked to human aortic aneurysms. By combining comprehensive genetic studies in the fruit fly, dataset searches and analysis of diseased human aortic tissue, the researchers shed light on mechanisms not previously known to be associated with this devastating disease.

24 Apr 2018

Researchers find crucial links between dopamine and avoidance behavior

Scientists at the University of Maryland School of Medicine have for the first time found direct causal links between the neurotransmitter dopamine and avoidance – behavior related to pain and fear.

20 Apr 2018

Study reveals surprising insights into RNA-binding proteins

A host of special molecules called nuclear RNA-binding proteins (RBPs), when misplaced outside the nucleus, form the harmful clumps seen in several brain disorders, including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).

20 Apr 2018

High-tech microscope reveals how cancer-causing virus anchors itself to human DNA

Using a homemade, high-tech microscope, scientists at the University of Virginia School of Medicine have revealed how a cancer-causing virus anchors itself to our DNA. That discovery could pave the way for doctors to cure incurable diseases by flushing out viruses, including HPV and Epstein-Barr, that now permanently embed themselves in our cells.

20 Apr 2018

Biologists discover surprising, additional function for soluble form of SNARE protein

In 2013, the Nobel Prize in Physiology or Medicine was awarded to three scientists for their contributions to uncovering the mechanisms governing vesicle transport in cells. Their explanations provided both a conceptual and a mechanistic understanding of basic processes at the most fundamental level.

13 Apr 2018

Researchers discover how 'junk DNA' plays key role in holding the genome together

Researchers at the University of Michigan Life Sciences Institute and the Howard Hughes Medical Institute have determined how satellite DNA, considered to be "junk DNA," plays a crucial role in holding the genome together.

11 Apr 2018

Resistance training enhances cellular recycling in muscle cells

A new study has shown that resistance training among previously untrained men increases autophagosome content, but that this effect may be blunted by aging.

9 Apr 2018

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

In a review article published April 5 in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics.

6 Apr 2018

Stable proteins in the brain offer clues to long-term memory and learning in mice

In the tiny brain space where two nerve cells meet, chemical and electric signals shuttle back and forth, a messaging system that ebbs and flows in those synaptic spaces, sometimes in ways that scientists believe aid and abet learning and memory.

3 Apr 2018

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis.

2 Apr 2018

Biophysical mechanism involving spaghetti-like proteins helps cells avoid 'data breaches'

Cells can avoid "data breaches" when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of Medicine have shown.

28 Mar 2018

UTA researchers take advantage of biochemistry technique to identify rare radioactive decays

UTA researchers are leading an international team developing a new device that could enable physicists to take the next step toward a greater understanding of the neutrino, a subatomic particle that may offer an answer to the lingering mystery of the universe's matter-antimatter imbalance.

28 Mar 2018

Research reveals why older people struggle to get a good night’s sleep

New research has identified the way age impairs the ability of the circadian clock in mammals to re-set itself when exposed to light, resulting in disruption to sleeping patterns and consequent threats to wellbeing

27 Mar 2018

USC researchers launch global project that aims to curb worldwide rise of diabetes

USC researchers have launched a massive scientific effort to construct a detailed, virtual 3-D model of the pancreatic beta cell and its components -- a global project that aims to one day curb the worldwide rise of diabetes.

26 Mar 2018

Researchers succeed in integrating artificial organelles into cells of living organism

For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of living zebrafish embryos.

20 Mar 2018

New study identifies key role for particular gene in 16p11.2 deletion syndrome

In a new study of one of the most common genetic causes of autism, neuroscientists at MIT's Picower Institute for Learning and Memory have identified a specific molecular mechanism that appears to undermine the ability of neurons in affected mice to properly incorporate changes driven by experience.

20 Mar 2018

Scientists uncover new answers to cell aging in children with rare, fatal disease

In a recent paper published in Cell Reports, Saint Louis University researchers have uncovered new answers about why cells rapidly age in children with a rare and fatal disease.

20 Mar 2018

Scientists discover basic molecular mechanism that helps understand how ALS works

It took eight long years of research, but now an international team led by neuroscientists at Université de Montréal has discovered a basic molecular mechanism that better helps understand how Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), works.

19 Mar 2018

Discovery aids understanding of amyotrophic lateral sclerosis

Researchers have discovered a basic molecular mechanism that sheds light on the disease process underlying amyotrophic lateral sclerosis (ALS).

19 Mar 2018

Researchers delineate architecture of nuclear pore complex in yeast cells

Like an island nation, the nucleus of a cell has a transportation problem. Evolution has enclosed it with a double membrane, the nuclear envelope, which protects DNA but also cuts it off from the rest of the cell. Nature's solution is a massive--by molecular standards--cylindrical configuration known as the nuclear pore complex, through which imports and exports travel, connecting the bulk of the cell with its headquarters.

16 Mar 2018

Cell Nucleus News and Research

Researchers discover new gene associated with aortic aneurysms

Researchers find crucial links between dopamine and avoidance behavior

Study reveals surprising insights into RNA-binding proteins

High-tech microscope reveals how cancer-causing virus anchors itself to human DNA

Biologists discover surprising, additional function for soluble form of SNARE protein

Researchers discover how 'junk DNA' plays key role in holding the genome together

Resistance training enhances cellular recycling in muscle cells

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

Stable proteins in the brain offer clues to long-term memory and learning in mice

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Biophysical mechanism involving spaghetti-like proteins helps cells avoid 'data breaches'

UTA researchers take advantage of biochemistry technique to identify rare radioactive decays

Research reveals why older people struggle to get a good night’s sleep

USC researchers launch global project that aims to curb worldwide rise of diabetes

Researchers succeed in integrating artificial organelles into cells of living organism

New study identifies key role for particular gene in 16p11.2 deletion syndrome

Scientists uncover new answers to cell aging in children with rare, fatal disease

Scientists discover basic molecular mechanism that helps understand how ALS works

Discovery aids understanding of amyotrophic lateral sclerosis

Researchers delineate architecture of nuclear pore complex in yeast cells

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