Embryonic Stem Cells News and Research

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Repression of PTB protein in fibroblasts can convert pluripotent stem cells into functional neurons

Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells - abundantly found in connective tissues - into functional neurons. The findings, which could have far-reaching implications for the development of new treatments for neurodegenerative diseases like Huntington's, Parkinson's and Alzheimer's, will be published online in advance of the January 17 issue of the journal Cell.

11 Jan 2013

Baboon embryonic stem cells can be programmed to completely restore severely damaged arteries

Scientists at the Texas Biomedical Research Institute have for the first time demonstrated that baboon embryonic stem cells can be programmed to completely restore a severely damaged artery. These early results show promise for eventually developing stem cell therapies to restore human tissues or organs damaged by age or disease.

11 Jan 2013

Apparent stem cell transplant success in mice may hold promise for people with ALS

Apparent stem cell transplant success in mice may hold promise for people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease.

11 Jan 2013

High court turns away challenge to Obama administration stem cell policy

Meanwhile, the Supreme Court heard arguments in a case involving Medicaid and malpractice awards. In addition, the justices rejected an appeal from Social Security recipients who don't want Medicare benefits.

9 Jan 2013

Researchers develop new materials to support stem cell growth

Stem cell manufacturing for drug screening and treatments for diseases such as Huntington's and Parkinson's could be boosted by a new method of generating stem cells, a study suggests.

9 Jan 2013

Study shows how to prod stem cells to become 2 different types of blood vessel tissues

Growing new blood vessels in the lab is a tough challenge, but a Johns Hopkins engineering team has solved a major stumbling block: how to prod stem cells to become two different types of tissue that are needed to build tiny networks of veins and arteries.

21 Dec 2012

Oscillation of gene activity may underlie how embryos grow in proportion

From a single-cell egg to a fully functional body: as embryos develop and grow, they must form organs that are in proportion to the overall size of the embryo. The exact mechanism underlying this fundamental characteristic, called scaling, is still unclear. However, a team of researchers from EMBL Heidelberg is now one step closer to understanding it.

21 Dec 2012

New work on Akt's role in cancer stem cell biology

The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, PhD and Weihua Li, co-first author, both from the Center for Resuscitation Sciences, Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, and Xiaowei Xu, Department of Pathology and Laboratory Medicine, appears in Molecular Cell.

21 Dec 2012

Two recent experimental treatments improve visual function in mouse models of retinitis pigmentosa

Two recent experimental treatments - one involving skin-derived induced pluripotent stem (iPS) cell grafts, the other gene therapy - have been shown to produce long-term improvement in visual function in mouse models of retinitis pigmentosa (RP), according to the Columbia University Medical Center (CUMC) scientists who led the studies. At present, there is no cure for RP, the most common form of inherited blindness.

20 Dec 2012

Viewpoints: Raising Medicare's entitlement age doesn't save money; New anti-fraud efforts

Looking for ways to slow the growth of entitlement programs, budget negotiators in Washington are considering making seniors wait two years longer to qualify for Medicare - from age 65 to 67. Many Republicans have endorsed the idea, noting that Medicare beneficiaries now live far longer on average than they did when Congress created the program in 1965.

18 Dec 2012

Tbx18 gene directs conversion of cardiomyocytes to genuine pacemaker cells

Cedars-Sinai Heart Institute researchers have reprogrammed ordinary heart cells to become exact replicas of highly specialized pacemaker cells by injecting a single gene (Tbx18)-a major step forward in the decade-long search for a biological therapy to correct erratic and failing heartbeats.

18 Dec 2012

American Association of Anatomist announces winners of Young Investigator Awards

The American Association of Anatomist's (AAA) Young Investigator Awards combine three long-standing AAA awards-Bensley, Herrick, and Mossman-with the Morphological Sciences Award, all recognizing investigators in the early stages of their careers who have made important contributions to biomedical science through their research in cell/molecular biology, developmental biology, comparative neuroanatomy, or the morphological sciences.

12 Dec 2012

New method promises to boost stem cell production in laboratory

A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.

5 Dec 2012

USPTO approves patent for Axiogenesis’ in vitro drug discovery assay to treat HCM

The USPTO approved a patent for Axiogenesis AG for the invention of its in vitro assay to screen pharmaceutical drug candidates for effectiveness and safety in treating Hypertrophic Cardiomyopathy (HCM).

5 Dec 2012

microRNAs play an important role during embryonic development

Sanford-Burnham researchers discover that microRNAs play an important role in germ layer formation-the process that determines which cells become which organs during embryonic development

3 Dec 2012

Answers to the questions of stem cells

Next week, more than 1,200 people from 25 countries are expected to attend the 8th Annual World Stem Cell Summit in West Palm Beach, Fla., a gathering co-sponsored by Mayo Clinic. As those close to the science explore potential stem cell applications, many patients have questions about what stem cells are and how they are being used. Timothy Nelson, M.D., Ph.D., director of Mayo Clinic's Regenerative Medicine Consult Service, answers some of the most commonly asked questions about stem cells.

29 Nov 2012

Breakthrough in heart research

Breakthrough in heart research: The research team from Professor Katja Schenke-Layland of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart has discovered cell surface markers that enable the identification and isolation of living functional cardiovascular progenitor cells (CPCs).

22 Nov 2012

Overexpression of BCL6 results in transformation of neural stem cells into cortical neurons

The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases.

19 Nov 2012

Induced-pluripotent stem cells not as genetically unstable as previously thought

Stanford University School of Medicine scientists have demonstrated, in a study conducted jointly with researchers at Yale University, that induced-pluripotent stem cells - the embryonic-stem-cell lookalikes whose discovery a few years ago won this year's Nobel Prize in medicine - are not as genetically unstable as was thought.

19 Nov 2012

New way to stimulate transplanted human stem cell-derived neurons into a rodent hippocampus

Researchers and patients look forward to the day when stem cells might be used to replace dying brain cells in Alzheimer's disease and other neurodegenerative conditions. Scientists are currently able to make neurons and other brain cells from stem cells, but getting these neurons to properly function when transplanted to the host has proven to be more difficult.

17 Nov 2012

Embryonic Stem Cells News and Research

Repression of PTB protein in fibroblasts can convert pluripotent stem cells into functional neurons

Baboon embryonic stem cells can be programmed to completely restore severely damaged arteries

Apparent stem cell transplant success in mice may hold promise for people with ALS

High court turns away challenge to Obama administration stem cell policy

Researchers develop new materials to support stem cell growth

Study shows how to prod stem cells to become 2 different types of blood vessel tissues

Oscillation of gene activity may underlie how embryos grow in proportion

New work on Akt's role in cancer stem cell biology

Two recent experimental treatments improve visual function in mouse models of retinitis pigmentosa

Viewpoints: Raising Medicare's entitlement age doesn't save money; New anti-fraud efforts

Tbx18 gene directs conversion of cardiomyocytes to genuine pacemaker cells

American Association of Anatomist announces winners of Young Investigator Awards

New method promises to boost stem cell production in laboratory

USPTO approves patent for Axiogenesis’ in vitro drug discovery assay to treat HCM

microRNAs play an important role during embryonic development

Answers to the questions of stem cells

Breakthrough in heart research

Overexpression of BCL6 results in transformation of neural stem cells into cortical neurons

Induced-pluripotent stem cells not as genetically unstable as previously thought

New way to stimulate transplanted human stem cell-derived neurons into a rodent hippocampus

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