Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

1 Dec 2022

Lower frequency of dietary salt associated with reduced risk of heart disease

Adding additional salt to foods at a lower frequency is associated with a reduced risk of heart disease, heart failure and ischemic heart disease, according to a new study published today in the Journal of the American College of Cardiology.

28 Nov 2022

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

In an intensive look at the effects of the virus causing COVID-19 on patients' microbiome – the collection of microorganisms that live in and on the human body – Rutgers scientists found that acute infection disrupts a healthy balance between good and bad microbes in the gut, especially with antibiotic treatment.

28 Nov 2022

Study: Nearly 1 in 7 Americans regularly experience bloating issues

Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren't seeking professional care for it, according to a new study led by Cedars-Sinai investigators.

24 Nov 2022

Survey: Two-thirds of European dietitians believe drinking coffee in moderation has clear health benefits

A new report by the European Federation of the Associations of Dietitians, supported by the Institute for Scientific Information on Coffee, has revealed that almost two-thirds (62%) of European dietitians believe drinking coffee in moderation has clear health benefits, with 86% agreeing that regular moderate intake can improve alertness and 69% agreeing that regular, moderate intake is associated with an improvement in overall sports performance.

22 Nov 2022

Low-dose CT screening improves survival rate of lung cancer patients

Diagnosing early-stage lung cancer with low-dose computed tomography (CT) screening drastically improves the survival rate of cancer patients over a 20-year period, according to a large-scale international study being presented by Mount Sinai researchers at the annual meeting of the Radiological Society of North America.

22 Nov 2022

Dietary change could be a key to enhancing colon cancer treatment

A dietary change could be a key to enhancing colon cancer treatment, a new study from the University of Michigan Rogel Cancer Center finds.

20 Nov 2022

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

A new molecular imaging radiotracer can precisely diagnose a variety of cancers, providing a roadmap to identify patients who may benefit from targeted radionuclide therapies.

20 Nov 2022

New AI blood testing technology detects more than 80% of liver cancers

A novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers to successfully detect lung cancer in a 2021 study has now detected more than 80% of liver cancers in a new study of 724 people.

20 Nov 2022

Sick profit: Investigating private equity’s stealthy takeover of health care across cities and specialties

Two-year-old Zion Gastelum died just days after dentists performed root canals and put crowns on six baby teeth at a clinic affiliated with a private equity firm.

14 Nov 2022

Study shows inherited risk factors for appendiceal cancer

One of every 10 patients with appendiceal cancer carries a germline genetic variant associated with cancer predisposition, according to a study in JAMA Oncology that is the first to show inherited risk factors for this rare cancer.

11 Nov 2022

Study helps understand the basis of sex differences in SARS-CoV-2 infection

Significant immunological differences between young men and women were shown to mediate sex differences in the responses to the virus that causes COVID-19, according to a collaborative study of nearly 3,000 young, healthy members of the U.S. Marine Corps.

8 Nov 2022

Researchers identify therapies for multiple myeloma patients whose cancer relapses after CAR-T

Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an immunotherapy known as CAR-T only to find their cancer coming back afterwards.

4 Nov 2022

H pylori eradication protects against aspirin-associated peptic ulcer bleeding

A new study, led by experts at the University of Nottingham found that the risk of stomach bleeding caused by using aspirin long-term, can be reduced with a short course of antibiotics, potentially improving the safety of aspirin when used to prevent heart attacks, strokes and possibly some cancers.

4 Nov 2022

Study determines the diagnostic utility of liver stiffness measurement

Even after chronic hepatitis C has been cured, portal hypertension remains the major factor driving the development of complications in advanced liver disease. In cooperation with researchers from Spain, a research team led by Georg Semmler and Mattias Mandorfer from the Division of Gastroenterology and Hepatology at MedUni Vienna's Department of Medicine III showed that the non-invasive tests explored in their earlier studies accurately estimate the probability of sequelae.

3 Nov 2022

Sophisticated tool helps measure exposure levels to PFAS

A novel metric that estimates our "burden," or cumulative exposure, to a family of thousands of synthetic chemicals that we encounter in everyday life with potentially adverse health impacts, has been created by a team of researchers at Mount Sinai.

2 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Approximately one-fourth of the general population worldwide has nonalcoholic fatty liver disease, known as NAFLD, an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. NAFLD can lead to cirrhosis, liver cancer and liver failure.

1 Nov 2022

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

The Breast Cancer Research Foundation (BCRF) has renewed its funding to Elisa Port, MD, and Hanna Irie, MD, PhD, to study new therapeutic approaches that target aggressive triple-negative breast cancer.

31 Oct 2022

Gastroenterology News and Research

Further Reading

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Lower frequency of dietary salt associated with reduced risk of heart disease

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

Study: Nearly 1 in 7 Americans regularly experience bloating issues

Survey: Two-thirds of European dietitians believe drinking coffee in moderation has clear health benefits

Low-dose CT screening improves survival rate of lung cancer patients

Dietary change could be a key to enhancing colon cancer treatment

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

New AI blood testing technology detects more than 80% of liver cancers

Sick profit: Investigating private equity’s stealthy takeover of health care across cities and specialties

Study shows inherited risk factors for appendiceal cancer

Study helps understand the basis of sex differences in SARS-CoV-2 infection

Researchers identify therapies for multiple myeloma patients whose cancer relapses after CAR-T

H pylori eradication protects against aspirin-associated peptic ulcer bleeding

Study determines the diagnostic utility of liver stiffness measurement

Sophisticated tool helps measure exposure levels to PFAS

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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