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Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis.

25 Oct 2019

TB is not a life-long infection in most people

A new analysis challenges the longstanding notion that tuberculous infection is a life-long infection that could strike at any time and cause tuberculosis. Based on a review of clinical studies, researchers from the Perelman School of Medicine at the University of Pennsylvania and colleagues show that people who test positive with immunologic TB skin or blood tests rarely develop TB.

25 Oct 2019

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

An international team of experts led by researchers in the Perelman School of Medicine at the University of Pennsylvania and University of Glasgow has been awarded a $9.7 million, five-year grant from the National Institute of Neurological Disorders and Stroke and National Institute for Aging to establish CONNECT-TBI--a program spanning 12 institutions which will study traumatic brain injury and related neurodegenerative diseases.

24 Oct 2019

Acetate derived from alcohol metabolism directly influences epigenetic regulation in the brain

Triggers in everyday life such as running into a former drinking buddy, walking by a once-familiar bar, and attending social gatherings can all cause recovering alcoholics to "fall off the wagon."

24 Oct 2019

Research aims to find factors that influence decision making about aging-in-place for older adults

For many older adults, aging-in-place, or remaining in their own home as they age, is a priority. Decision making and planning is critical to successful aging-in-place, yet often older adults defer decisions about their aging-in-place and long-term care needs.

24 Oct 2019

Study finds high number of hospital return for preexisting or linked infections

About 15% of hospitalized older adults will be readmitted within a month of discharge.

23 Oct 2019

Support coaches for smoother transitions to home care and postoperative recovery

With healthcare being an ever-changing landscape, bundled payments are becoming a more popular option for hospitals since it allows physicians to allocate a set amount of money to cover a patient's stay from their hospital admission all the way up to 90 days after their procedure.

22 Oct 2019

Penn researcher-led study aims to improve long-term outcomes of lung transplants

Lung transplantation can be a life-extending option, but severe postoperative complications-including reduced lung function caused by organ rejection-often affect a recipients' quality of life and limit long-term survival.

17 Oct 2019

Study compares costs, outcomes of surgeries at teaching and non-teaching hospitals

Patients with a high risk of dying after surgery, including those with multiple chronic diseases, benefit from undergoing general or vascular procedures at a major teaching hospital as opposed to a non-teaching hospital, according to a study from researchers at Penn Medicine and the Children's Hospital of Philadelphia.

17 Oct 2019

Study reveals new and surprising function of adenine nucleotide translocator

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear.

16 Oct 2019

Sepsis Alliance launches online learning platform to provide high quality sepsis education

Today, Sepsis Alliance, the nation’s first and leading sepsis organization, announced the launch of The Sepsis Institute, an online learning platform that provides healthcare professionals across the continuum of care with high quality, evidence-based sepsis education and training to improve diagnosis and outcomes for the millions who are harmed by sepsis every year in the United States.

15 Oct 2019

Changes to state law reduce new opioid prescriptions by 22% in Penn Medicine’s New Jersey practices

The total amount of opioids dispensed per new opioid prescription decreased by 22 percent in Penn Medicine outpatient practices in New Jersey after the state passed a law limiting prescriptions to a five-day supply for new opioid prescriptions.

14 Oct 2019

Women's voices are less influential on Twitter than male peers in academic medicine

Women who are health policy or health services researchers face a significant disparity in social media influence compared to their male peers, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

14 Oct 2019

New algorithm hand-picks which cancer mutations are promising targets for immunotherapy

As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack.

9 Oct 2019

Study aims to help stratify risks associated with new devices for treating pulmonary embolism

Pulmonary embolism (PE), a blood clot lodged in one of the pulmonary arteries in the lungs, is the third leading cause of cardiovascular-related death in the United States. While most patients are treated with anticoagulants (commonly known as blood thinners), the use of novel interventional devices that remove or dissolve clots in the lungs has significantly increased in recent years.

5 Oct 2019

Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

The nation has been grappling with the opioid epidemic for years - and the city of Philadelphia has been hit hard by the crisis. While data is showing slight declines in overdose deaths, the opioid crisis remains a public health emergency.

4 Oct 2019

Penn researchers propose ethical framework that defines brain organoid transplantation

As research involving the transplantation of human "mini-brains"--known as brain organoids--into animals to study disease continues to expand, so do the ethical debates around the practice.

4 Oct 2019

Study shows how caregivers can better manage family conflict at end of life

Conflict within families can be stressful and confusing, and it can lead to feelings of sadness. It also is incredibly common and in many cases, a necessary part of family dynamics.

3 Oct 2019

The Slaight Family Foundation supports UHN to deliver enhanced care for seniors outside the hospital

The Silver Tsunami will see an unprecedented number of seniors in Canada, which is also true throughout North America.

1 Oct 2019

Penn researchers win NIA grant to study link between Alzheimer's, dementia, and Parkinson's

The Center for Neurodegenerative Disease Research (CNDR) at the University of Pennsylvania has received a grant expected to total $18.1 million to study the underlying genetic mechanisms that cause Alzheimer's Disease, Dementia, and Parkinson's Disease to progress as well as how those mechanisms are related to each other and to the cell-to-cell spread of these disease proteins.

30 Sep 2019

Home Care News and Research

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

TB is not a life-long infection in most people

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

Acetate derived from alcohol metabolism directly influences epigenetic regulation in the brain

Research aims to find factors that influence decision making about aging-in-place for older adults

Study finds high number of hospital return for preexisting or linked infections

Support coaches for smoother transitions to home care and postoperative recovery

Penn researcher-led study aims to improve long-term outcomes of lung transplants

Study compares costs, outcomes of surgeries at teaching and non-teaching hospitals

Study reveals new and surprising function of adenine nucleotide translocator

Sepsis Alliance launches online learning platform to provide high quality sepsis education

Changes to state law reduce new opioid prescriptions by 22% in Penn Medicine’s New Jersey practices

Women's voices are less influential on Twitter than male peers in academic medicine

New algorithm hand-picks which cancer mutations are promising targets for immunotherapy

Study aims to help stratify risks associated with new devices for treating pulmonary embolism

Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

Penn researchers propose ethical framework that defines brain organoid transplantation

Study shows how caregivers can better manage family conflict at end of life

The Slaight Family Foundation supports UHN to deliver enhanced care for seniors outside the hospital

Penn researchers win NIA grant to study link between Alzheimer's, dementia, and Parkinson's

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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