Low Density Lipoprotein (LDL) News and Research

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Foods that can reduce cholesterol

At present those with cholesterol are prescribed cholesterol lowering drugs like statins and a diet that cuts out foods high in saturated fat. New research shows that some foods may help to lower cholesterol.

26 Aug 2011

ESC introduces update to HeartScore application

The number of heart attack and stroke incidents in Europe is likely to reduce with the imminent launch of an update to the HeartScore® application. HeartScore® was first developed by the European Society of Cardiology (ESC) in 2004, and it helps clinicians rapidly estimate the risk of cardiovascular disease (CVD) in individual patients using age, gender, basic health indicators, and lifestyle factors.

26 Aug 2011

New test to better predict heart attack risk in women

The biggest killer of women over the age of 50 is heart disease. By age 65 women have the same heart attack or stroke risk as men and a greater risk of dying from either. To help better predict heart attack risk in these women, Atherotech Diagnostics Lab has developed a new and better way to test for heart disease risk. The new test will soon be available exclusively through Atherotech Diagnostics Lab.

26 Aug 2011

Hearing dietary advice twice is enough for patients to get benefits of lower cholesterol

Hearing dietary advice twice is enough for patients to get the significant benefits of lower cholesterol, according to a new study led by doctors at St. Michael's Hospital and the University of Toronto.

25 Aug 2011

CHL completes $18.4-million Series B financing round

Cleveland HeartLab Inc. (CHL), a leading specialty clinical laboratory and disease management company, today announced the completion of an $18.4-million Series B financing round.

23 Aug 2011

High levels of calcium in coronary arteries increase risk of stroke, heart attack

The presence of calcium in coronary arteries is a much better predictor of heart attack and stroke than C-reactive protein among people with normal levels of LDL cholesterol, according to a study of more than 2,000 people led by a Johns Hopkins heart specialist.

19 Aug 2011

Single-molecule imaging reveals how cells prepare to interact with biochemical signals

Researchers at Harvard Medical School have discovered that structural elements in the cell play a crucial role in organizing the motion of cell-surface receptors, proteins that enable cells to receive signals from other parts of the organism.

19 Aug 2011

Bill Clinton on being ‘vegan’

Former President Bill Clinton has revealed that his diet is turning plant-based and heart-healthy. He said he believes the vegan regimen is helping to reverse the damage to his heart and blood vessels caused by cardiovascular disease.

18 Aug 2011

Fibrate drugs may not prevent heart attacks in diabetes patients with elevated cholesterol

Type 2 diabetes patients, who face higher risk of cardiovascular disease, often take a combination of medications designed to lower their LDL or "bad" cholesterol and triglyceride levels while raising their HDL or "good" cholesterol because doctors long have thought that taken together, the drugs offer protection from heart attacks and improve survival.

12 Aug 2011

Feed for hens decides health of eggs

Eggs, one of the most commonly consumed breakfast foods in the United States, have long been a subject of controversy. Are they healthy or are they a high-cholesterol trap? The answer depends on what the hen eats, says a Tel Aviv University researcher.

3 Aug 2011

High fructose corn syrup consumption may promote heart disease

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that adults who consumed high fructose corn syrup for two weeks as 25 percent of their daily calorie requirement had increased blood levels of cholesterol and triglycerides, which have been shown to be indicators of increased risk for heart disease.

29 Jul 2011

Study: Mail-order pharmacy use linked to improved cardiovascular risk factor outcomes

Kaiser Permanente Northern California patients who obtained new statin prescriptions via a mail-order pharmacy achieved better cholesterol control in the first 3-15 months following the initiation of therapy -- compared to those patients who only obtained their statin prescription from their local Kaiser Permanente Northern California pharmacy.

25 Jul 2011

Isis commences ISIS-PTP1BRx Phase 1 study in type 2 diabetes

Isis Pharmaceuticals, Inc. announced today that it has initiated a Phase 1 clinical study for ISIS-PTP1BRx, an antisense drug for the treatment of type 2 diabetes targeting protein tyrosine phosphatase-1B, PTP-1B.

21 Jul 2011

Researchers identify IDOL protein as potential new target for lowering LDL cholesterol

High levels of 'bad' cholesterol (LDL cholesterol) are a risk factor for developing atherosclerotic cardiovascular disease (ASCVD) - a disease of the major arterial blood vessels that is one of the major causes of heart attack and stroke.

21 Jul 2011

ISENTRESS demonstrates comparable efficacy to efavirenz in treatment-naïve adult HIV-1 patients

Merck, known as MSD outside the United States and Canada, today announced final results from a Phase II clinical study, extending out to 240 weeks, of its integrase inhibitor ISENTRESS® (raltegravir) Tablets in combination therapy in previously untreated (treatment-naïve) adult HIV-1-infected patients.

18 Jul 2011

B. Braun adds Plasmat Futura System to H.E.L.P. LDL Apheresis therapy

The Renal Therapies Division of B. Braun Medical Inc. (B. Braun) announced today the availability of the Plasmat Futura System for H.E.L.P. LDL Apheresis therapy.

From B. Braun Melsungen AG 15 Jul 2011

Patient-centered medical home boosts diabetes outcomes, health

A health-care delivery model called patient-centered medical home (PCMH) increased the percentage of diabetes patients who achieved goals that reduced their sickness and death rates, according to health researchers.

14 Jul 2011

Study: Modified fat diet might reduce risk of heart disease

The debate between good fat versus bad fat continues, as a new evidence review finds that a modified fat diet — and not a low fat diet — might be the real key to reducing one's risk of heart disease.

13 Jul 2011

Eating nuts daily could help control type 2 diabetes and prevent complications

Eating nuts every day could help control Type 2 diabetes and prevent its complications, according to new research from St. Michael's Hospital and the University of Toronto.

13 Jul 2011

Alnylam seeks CTA clearance to initiate ALN-PCS Phase I clinical trial for severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has filed a Clinical Trial Application (CTA) with the Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase I clinical trial with ALN-PCS, an RNAi therapeutic for the treatment of severe hypercholesterolemia.

11 Jul 2011

Low Density Lipoprotein (LDL) News and Research

Foods that can reduce cholesterol

ESC introduces update to HeartScore application

New test to better predict heart attack risk in women

Hearing dietary advice twice is enough for patients to get benefits of lower cholesterol

CHL completes $18.4-million Series B financing round

High levels of calcium in coronary arteries increase risk of stroke, heart attack

Single-molecule imaging reveals how cells prepare to interact with biochemical signals

Bill Clinton on being ‘vegan’

Fibrate drugs may not prevent heart attacks in diabetes patients with elevated cholesterol

Feed for hens decides health of eggs

High fructose corn syrup consumption may promote heart disease

Study: Mail-order pharmacy use linked to improved cardiovascular risk factor outcomes

Isis commences ISIS-PTP1BRx Phase 1 study in type 2 diabetes

Researchers identify IDOL protein as potential new target for lowering LDL cholesterol

ISENTRESS demonstrates comparable efficacy to efavirenz in treatment-naïve adult HIV-1 patients

B. Braun adds Plasmat Futura System to H.E.L.P. LDL Apheresis therapy

Patient-centered medical home boosts diabetes outcomes, health

Study: Modified fat diet might reduce risk of heart disease

Eating nuts daily could help control type 2 diabetes and prevent complications

Alnylam seeks CTA clearance to initiate ALN-PCS Phase I clinical trial for severe hypercholesterolemia

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