Myeloma News and Research

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New therapeutic approach offers hope for individuals with debilitating bone cancer

An Australian-led research team has demonstrated a new therapeutic approach that can re-build and strengthen bone, offering hope for individuals with the debilitating bone cancer, multiple myeloma.

29 Jun 2017

UAMS scientists show potential of world's smallest laser to kill single cancer cells

A University of Arkansas for Medical Sciences research team led by Vladimir Zharov, Ph.D., D.Sc., has demonstrated the ability to kill single cancer cells using the world's smallest laser.

9 Jun 2017

New immunotherapy sends multiple myeloma into remission

Researchers are reporting the impressive results of a new cell and gene therapy that has achieved unprecedented success in treating multiple myeloma patients. Although the study is an early one and the population only included 35 people, every one of the patients responded to the treatment and 33 (94%) were in some degree of clinical remission within two months.

6 Jun 2017

New findings highlight possibility of developing specific cancer drugs with fewer side effects

Scientists at Karolinska Institutet in Sweden report that cancer cells and normal cells use different 'gene switches' in order to regulate the expression of genes that control growth.

6 Jun 2017

Researchers uncover new way to enhance function of immune cells to combat multiple myeloma

Researchers from Belgium led by Prof. Dirk Elewaut of the VIB-UGent Center for Inflammation Research and the team of Prof. Vanderkerken and Prof. Menu at the Hematology and Immunology lab of the VUB uncovered a new way to enhance the function of a specific type of immune cell that destroys tumors in multiple myeloma, a form of bone marrow cancer considered incurable.

1 Jun 2017

Study shows how different genetic mutations cause acute myeloid leukemia

A study led by the University of Birmingham has made a breakthrough in the understanding of how different genetic mutations cause acute myeloid leukemia.

23 May 2017

New technology could hold key to predicting outcome of blood cancer patients

Technology that can detect the length of small DNA structures in cancer cells could hold the key to predicting the outcome of patients with two different types of blood cancer.

11 May 2017

New treatment offers hope for kidney failure and transplant patients with rare disorder

A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research.

3 May 2017

Hematologist-oncologist to lead bone marrow transplantation program for treating blood-borne cancers

Hematologist-oncologist Ahmad Samer Al-Homsi MD, MBA, will lead a new bone marrow transplantation program at NYU Langone's Perlmutter Cancer Center for treating blood-borne cancers, including leukemia, lymphoma and multiple myeloma, and potentially utilize transplantation as an adjunct to immunotherapy for solid tumors.

10 Apr 2017

New microfluidic technique may provide patients with less painful test for multiple myeloma

Multiple myeloma is a cancer of the plasma cells, which are white blood cells produced in bone marrow that churn out antibodies to help fight infection. When plasma cells become cancerous, they produce abnormal proteins, and the cells can build up in bone marrow, ultimately seeping into the bloodstream.

4 Apr 2017

Researchers discover how epigenetic lesion can lead to T-cell acute lymphoblastic leukemia

Researchers from the Epigenetics and Cancer Biology Program led by Dr. Manel Esteller at the Bellvitge Biomedical Research Institute have discovered how an epigenetic lesion can lead to T-cell acute lymphoblastic leukemia.

30 Mar 2017

TSRI researchers develop novel drug delivery method for treating cancers

Scientists from the Florida campus of The Scripps Research Institute have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.

16 Mar 2017

Clinical trials – how can patients get the most benefit out of them?

Putting patients at the centre of clinical trial research is perhaps something that goes without saying. At the Clinical Innovation and Partnering World congress in London last week, this was much discussed, along with the need to increase efforts into engaging patients to take part in clinical trials, and the fact that patients are sometimes suspicious of research because it is not explained enough and patient engagement is poor.

16 Mar 2017

Mayo Clinic researchers find new experimental drug that shrinks tumors in multiple myeloma patients

Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma. The findings are published in Nature Medicine.

8 Mar 2017

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental therapy in which patients' own immune cells are genetically engineered to fight their cancer.

1 Mar 2017

Novel antiviral drug can protect transplant patients against CMV infections

In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.

24 Feb 2017

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

If you've ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens.

22 Feb 2017

Treating multiple myeloma with rabbit virus eliminates majority of malignant cells, study shows

Treating multiple myeloma (MM) with myxoma virus (MYXV) eliminated a majority of malignant cells in preclinical studies, report investigators at the Medical University of South Carolina and elsewhere in an article published online on December 7, 2016 by Molecular Therapy -- Oncolytics.

22 Feb 2017

Researchers identify novel gene critical to development of lung and pancreatic cancer

Researchers at the Center for Applied Medical Research of the University of Navarra have identified a critical gene, FOSL1, in the development of lung and pancreatic cancer.

22 Feb 2017

Myeloma News and Research

New therapeutic approach offers hope for individuals with debilitating bone cancer

UAMS scientists show potential of world's smallest laser to kill single cancer cells

New immunotherapy sends multiple myeloma into remission

New findings highlight possibility of developing specific cancer drugs with fewer side effects

Researchers uncover new way to enhance function of immune cells to combat multiple myeloma

Study shows how different genetic mutations cause acute myeloid leukemia

New technology could hold key to predicting outcome of blood cancer patients

New treatment offers hope for kidney failure and transplant patients with rare disorder

Hematologist-oncologist to lead bone marrow transplantation program for treating blood-borne cancers

New microfluidic technique may provide patients with less painful test for multiple myeloma

Researchers discover how epigenetic lesion can lead to T-cell acute lymphoblastic leukemia

TSRI researchers develop novel drug delivery method for treating cancers

Clinical trials – how can patients get the most benefit out of them?

Mayo Clinic researchers find new experimental drug that shrinks tumors in multiple myeloma patients

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

Novel antiviral drug can protect transplant patients against CMV infections

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

Treating multiple myeloma with rabbit virus eliminates majority of malignant cells, study shows

Researchers identify novel gene critical to development of lung and pancreatic cancer

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