Nasopharyngeal News and Research

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Severity of COVID-19 correlates with the ratio of antibodies targeting crucial viral protein

COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine.

24 Dec 2020

Self-collected nasal swabs may provide a reliable alternative to nasopharyngeal swabs

Under certain conditions, antigen testing using self-collected swabs from the anterior nose may constitute a reliable alternative to antigen testing using nasopharyngeal swabs collected by health professionals.

22 Dec 2020

Study confirms the feasibility of RT-qPCR on extraction-free inactivated SARS-CoV-2 samples

A new paper reports superior results using an alternative test protocol for RT-qPCR testing for the SARS-CoV-2 virus.

21 Dec 2020

SARS-CoV-2 RNA in serum associated with poor prognosis and high mortality

A new preprint indicates the direct correlation between the presence of detectable viral RNA loads in serum, and clinical severity and death.

21 Dec 2020

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

A new paper that appeared as a preprint on the medRxiv* server in December 2020 describes a nucleic acid test validated on saliva samples.

18 Dec 2020

FDA issues emergency use authorization for first fully at-home OTC COVID-19 diagnostic test

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the first over-the-counter (OTC) fully at-home diagnostic test for COVID-19.

15 Dec 2020

Less sensitive rapid tests may miss asymptomatic/presymptomatic SARS-CoV-2 infection

The rapid transmissibility of SARS-CoV-2 has posed a significant challenge to COVID-19 containment measures.

14 Dec 2020

Case study suggests kindergartens are not SARS-CoV-2 super-spreaders

A new study by researchers at the Institute of Tropical Medicine and International Health at the Charite Universitaetsmedizin Berlin found that kindergartens are not silent transmission reservoirs.

11 Dec 2020

SARS-CoV-2 genetic material can be reliably detected in self-collected saliva samples

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have found that SARS-CoV-2 genetic material can be reliably detected in self-collected saliva samples at a rate similar to that of nasopharyngeal and oropharyngeal swabs.

11 Dec 2020

Researchers analyze prevalence of COVID-19 in human post-mortem ocular tissues

COVID-19 has been found in conjunctival swabs and tears of infected patients, according to a new study published in The Ocular Surface.

11 Dec 2020

Single N primer sufficient for SARS-CoV-2 molecular diagnosis

There is a huge and growing demand for better molecular diagnostic tests for COVID-19, as the pandemic shows few signs of coming under control.

10 Dec 2020

Could anterior nasal swabs be an effective alternative for SARS-CoV-2 testing?

Researchers from various institutions in Germany and Switzerland recently performed a prospective diagnostic accuracy study, in which they compared professional-collected anterior nasal swabs to nasopharyngeal swabs, using WHO-listed SARS-CoV-2 Ag-RDT (STANDARD Q COVID-19 Ag Test, SD Biosensor) test kits.

10 Dec 2020

COVID-19 may be linked to acute appendicitis in children

Researchers at the University of Virginia have recently presented a case series pointing to a potential association between infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the development of acute appendicitis in children.

8 Dec 2020

Saliva samples may be reliable alternative to nasal swabs for SARS-CoV-2 testing

A team of researchers from various institutes in Switzerland report how saliva samples may be a strong alternative to nasal swaps in PCR-related SARS-CoV-2 testing.

8 Dec 2020

Sensitivity of coronavirus antibody tests may be lower than stated on the package

A study by University of Tartu researchers indicates that the sensitivity of tests used to detect viral antibodies in a blood sample may differ significantly. The combination of several tests may give the best result.

3 Dec 2020

Asymptomatic patients have higher SARS-CoV-2 viral loads than symptomatic patients, study says

Now, a surprising new study shows that asymptomatic COVID-19 patients have greater viral loads than those with symptoms.

29 Nov 2020

Body mass index and severe COVID-19

French researchers led by first author Abdallah Al-Salameh from the Department of Endocrinology, Diabetes Mellitus and Nutrition, Amiens University Hospital, Amiens, France, have published findings of their study titled, “The association between body mass index class and coronavirus disease 2019 outcomes,” in the latest issue of the International Journal of Obesity.

26 Nov 2020

Researchers launch study to determine effects of increased access to rapid COVID-19 testing

Researchers at the University of Chicago Medicine and the University of Illinois at Chicago (UIC) are launching an investigational study to determine the effects of increased education and access to rapid, FDA-approved COVID-19 testing on community perceptions, access, and use of COVID-19 testing resources.

24 Nov 2020

Avacta Group announces significant progress in the development of SARS-CoV-2 rapid antigen test

Avacta Group plc, the developer of innovative cancer therapies and diagnostics based on its proprietary Affimer® and pre|CISION™ platforms, is pleased to announce significant progress in the development of a highly scalable manufacturing process for a lateral flow SARS-CoV-2 antigen test being carried out with BBI Solutions, and that the lateral flow test has very good analytical sensitivity with laboratory samples.

From Avacta Life Sciences Ltd. 24 Nov 2020

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

Wastewater surveillance has been reported to be a feasible and efficient way to monitor the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the current COVID-19 pandemic. A recent study draws attention to the need to freeze wastewater samples if the analysis is carried out later rather than immediately.

24 Nov 2020

Nasopharyngeal News and Research

Severity of COVID-19 correlates with the ratio of antibodies targeting crucial viral protein

Self-collected nasal swabs may provide a reliable alternative to nasopharyngeal swabs

Study confirms the feasibility of RT-qPCR on extraction-free inactivated SARS-CoV-2 samples

SARS-CoV-2 RNA in serum associated with poor prognosis and high mortality

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

FDA issues emergency use authorization for first fully at-home OTC COVID-19 diagnostic test

Less sensitive rapid tests may miss asymptomatic/presymptomatic SARS-CoV-2 infection

Case study suggests kindergartens are not SARS-CoV-2 super-spreaders

SARS-CoV-2 genetic material can be reliably detected in self-collected saliva samples

Researchers analyze prevalence of COVID-19 in human post-mortem ocular tissues

Single N primer sufficient for SARS-CoV-2 molecular diagnosis

Could anterior nasal swabs be an effective alternative for SARS-CoV-2 testing?

COVID-19 may be linked to acute appendicitis in children

Saliva samples may be reliable alternative to nasal swabs for SARS-CoV-2 testing

Sensitivity of coronavirus antibody tests may be lower than stated on the package

Asymptomatic patients have higher SARS-CoV-2 viral loads than symptomatic patients, study says

Body mass index and severe COVID-19

Researchers launch study to determine effects of increased access to rapid COVID-19 testing

Avacta Group announces significant progress in the development of SARS-CoV-2 rapid antigen test

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

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