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Vitamin C and thiamine plus steroids do not improve septic shock outcome finds study

A randomized clinical trial showed that combining Vitamin C and thiamine with standard steroid hydrocortisone did not improve the time of survival for patients with septic shock. The study titled, “Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial,” was published in the most recent issue of JAMA.

19 Jan 2020

Study quashes the idea of using vitamin C-based cocktail for treatment of sepsis

In 2017 a paper was published asserting that intravenous vitamin C given to patients with sepsis was literally a life saver. Despite the study only looking at 47 subjects the results garnered international coverage and was adopted in many ICUs worldwide.

17 Jan 2020

Mount Sinai ophthalmologists share tips for early detection of glaucoma

January is Glaucoma Awareness Month, and ophthalmologists at New York Eye and Ear Infirmary of Mount Sinai are urging high-risk groups to get comprehensive eye exams for early detection of this degenerative eye disease.

13 Jan 2020

Low-fat diet associated with reduction in testosterone among men

For the many men diagnosed with testosterone deficiency, losing weight can help increase testosterone levels.

11 Jan 2020

Researchers study the effects of antidepressants to identify the least harmful drugs

About one in ten women in Québec will suffer from depression during pregnancy. Without treatment, the illness carries risks for both mother and child.

8 Jan 2020

Study hints a link between disruptions to progesterone signaling and recurrent miscarriage

About twenty percent of confirmed pregnancies end in miscarriage, most often in the first trimester, for reasons ranging from infection to chromosomal abnormality.

6 Jan 2020

New antibody shows promise in active lupus

A new trial involving the use of an antibody called anifrolumab reports improvement in patients with systemic lupus erythematosus (SLE) after 52 weeks of treatment. The research, titled 'Trial of Anifrolumab in Active Systemic Lupus Erythematosus', is published in the New England Journal of Medicine.

19 Dec 2019

Lowering mouse allergen exposure may lead to improved lung growth in asthmatic children

Lowering exposure to allergens from mice may lead to improved lung growth for children with asthma living in low-income neighborhoods, helping them avoid lung ailments and possibly live longer, according to newly published research in The Journal of Allergy and Clinical Immunology.

19 Dec 2019

Pilot study shows strong results for genicular artery embolization to treat OA-related knee pain

A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis.

17 Dec 2019

Type of upper airway bacteria could influence asthma severity

A new study raises the possibility of modulating asthma symptoms via the bacteria that commonly live in the upper airway. The work, which was published on December 16, 2019, in the journal Nature Communications, shows that in children who have mild to moderate asthma, the microbiome of the upper airway could determine how severe the symptoms are.

16 Dec 2019

Early cholesterol checks could save your heart

A new study published in the journal The Lancet reports that early cholesterol checking in the 20s, for instance, would help forecast the individual’s risk of ever having a stroke or heart disease over a lifetime.

5 Dec 2019

Research shows how gut microbes affect stomach flu

A new study shows that gut microbes can modulate the severity of norovirus infection (the stomach flu, or the winter vomiting bug), based on the gut location first affected. Published in the journal Nature Microbiology on November 25, 2019, the study indicates new possibilities to treat norovirus infection.

26 Nov 2019

Medical steroid use could push up diabetes risk

Glucocorticoids (GCs), or steroids, as they are popularly called, are often prescribed for their anti-inflammatory effects in a host of conditions including acute asthmatic attacks, allergies, and arthritis. However, are they doing good or harm?

12 Nov 2019

Drug regimen for lymphoma and RA more likely to put patients with pemphigus into remission

Pemphigus, an autoimmune disease mediated by B cells and which causes painful blisters and sores on the skin and mucous membranes, is a rare chronic autoimmune condition that can be fatal if not treated.

11 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Early detection, treatment may reduce risk of death from systemic JIA-associated lung disease

For thousands of children living with the debilitating disease systemic juvenile idiopathic arthritis, a class of medications known as "biologics" have produced dramatic, life-changing improvements.

29 Oct 2019

Cancer drug may delay progression of bone and other myeloma-related organ damage

The largest randomized trial in asymptomatic patients with smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of bone and other myeloma-related organ damage.

28 Oct 2019

Autism spectrum disorder could be triggered by low placental steroid levels

A recent experimental study has shown that one reason for the occurrence of autism spectrum disorder (ASD) could be the deficit of a placental steroid hormone called allopregnanolone. The reason is that this hormone plays a critical role in the normal development of the brain in fetal life.

21 Oct 2019

Insufficient placental steroid may increase autism spectrum disorder risk

A study in experimental models suggests that allopregnanolone, one of many hormones produced by the placenta during pregnancy, is so essential to normal fetal brain development that when provision of that hormone decreases or stops abruptly - as occurs with premature birth - offspring are more likely to develop autism-like behaviors.

20 Oct 2019

Research: Alternative pathway to production of male hormones is present during human fetal development

Research led by the Universities of Birmingham and Manchester has made a connection between the way baby wallabies produce male hormones and how some human girls are born with genitalia that resemble those of a boy.

17 Oct 2019