Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Researchers discover nitroxoline can reduce human breast, bladder cancer cell growth

Researchers at the Johns Hopkins University School of Medicine have discovered that nitroxoline, an antibiotic commonly used around the world to treat urinary tract infections, can slow or stop the growth of human breast and bladder cancer cells by blocking the formation of new blood vessels.

20 Jan 2011

Legionnaires’ disease scare in Bali: Australian tourists warned

Commonwealth chief medical officer Jim Bishop has warned Australians who have returned from Bali on an outbreak of Legionnaires’ disease on the popular Indonesian resort island. The Australian health authorities knew of 11 cases of Legionnaires’ disease detected in Victorians and Western Australians after holidays in the Kuta area of Bali between August 2010 and January 2011.

19 Jan 2011

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

With an invention that can be made from some of the same parts used in CD players, University of Michigan researchers have developed a way to measure the growth and drug susceptibility of individual bacterial cells without the use of a microscope.

19 Jan 2011

PROLOR and Yeda enter definitive license agreement for Reversible PEGylation technology

PROLOR Biotech, Inc., today announced that it has entered into a definitive license agreement with Yeda Research and Development Company Ltd. for novel technology utilized in the development of long-acting therapeutic peptides and small molecules, termed Reversible PEGylation.

18 Jan 2011

Vaccine to prevent MRSA infections after bone and joint surgery

University of Rochester Medical Center orthopaedic scientists are a step closer to developing a vaccine to prevent life-threatening methicillin-resistant staphylococcus aureus (MRSA) infections following bone and joint surgery.

18 Jan 2011

Antibiotics with blood pressure medications may cause hypotension

Mixing commonly used antibiotics with common blood pressure medications may cause hypotension and induce shock in older patients, requiring hospitalization, according to a study published in CMAJ.

18 Jan 2011

Antibiotic treatment may be sufficient to overcome River Blindness

The team found that a bacterium inside the worm acts as a 'disguise' for the parasite, resulting in the immune system reacting to it in an ineffective way. The bacteria protect the worm from the body's natural defences, but once the bacteria are removed with antibiotics, the immune system responds appropriately, releasing cells, called eosinophils, that kill the worm.

13 Jan 2011

Antibiotics for ear infection in kids better than watchful waiting: Study

Findings from two latest clinical trials reveal that a young child with ear infections recovers faster and more completely if doctors give antibiotics right away rather than waiting to see if the kid get better on his/her own. One of the studies was in the U.S. and one in Finland. Earlier it has been debated that for young children with middle ear infections or otitis media whether immediate antibiotic treatment was better than watchful waiting. Current treatment recommendations in the U.S., Canada, and Europe allow for a watch-and-wait approach to suspected middle ear infections in young children. Change is coming, predicts study leader Alejandro Hoberman, MD, of Children’s Hospital of Pittsburgh.

12 Jan 2011

Private rooms in the ICU help reduce hospital infections

A research team from the McGill University Health Centre (MUHC) and McGill University has demonstrated that private rooms in the Intensive Care Unit (ICU) play a key role in reducing hospital infections like C-difficile. The study, published today in the journal Archives of Internal Medicine, also suggests that length of stay would be shorter and this could lead to cost savings to the healthcare system.

12 Jan 2011

Rib-X raises $20M to support development of broad spectrum antibiotics pipeline

Rib-X Pharmaceuticals, Inc. today announced that the Company has raised $20 million to support ongoing development of the Company's industry-leading broad spectrum antibiotics pipeline, including late-stage clinical development of delafloxacin, which is expected to enter a Phase 2b study in early 2011.

11 Jan 2011

Predator microbes may work against antibiotic resistant disease-causing bacteria: Study

There are predators in the bacterial world that consume other bacteria, much as predators attack prey in the animal world. A team led by researchers at the University of Medicine and Dentistry of New Jersey-New Jersey Dental School suggests that some of these predator microbes might be put to work against disease-causing bacteria that have become resistant to antibiotics.

11 Jan 2011

Obama administration sides with drug companies in pricing lawsuit; Supreme Court agrees to hear case regarding use of prescription drug data

At issue are charges to public hospitals and clinics that treat a large number of poor patients and a Vermont law that restricts prescription drug data.

10 Jan 2011

Targeted Genetics acquires Biocontrol

Targeted Genetics Corporation, today announced the completion of the acquisition of Biocontrol Limited.

7 Jan 2011

IDSA releases MRSA treatment guidelines

Physicians now have help in their battle against methicillin resistant Staphylococcus aureus (MRSA), a potentially deadly infection that initially was limited to hospitals and health care facilities but has become a growing problem in healthy children and adults. The Infectious Diseases Society of America (IDSA) has released its first guidelines for the treatment of increasingly common MRSA infections.

7 Jan 2011

Studies show XIFAXAN 550 mg tablets demonstrate significant relief of global IBS symptoms

Salix Pharmaceuticals, Ltd. today announced the New England Journal of Medicine has published results from TARGET 1 and TARGET 2, the Company's two pivotal Phase 3 efficacy and safety studies of XIFAXAN (rifaximin) 550 mg tablets for the treatment of Irritable Bowel Syndrome without constipation, or Non-C IBS.

6 Jan 2011

Columbia research team identifies bacteria may play a key role in atherosclerosis

Dr. Emil Kozarov and a team of researchers at the Columbia University College of Dental Medicine have identified specific bacteria that may have a key role in vascular pathogenesis, specifically atherosclerosis, or what is commonly referred to as "hardening of the arteries" - the number one cause of death in the United States.

6 Jan 2011

Bacteria adopt defence strategy to promote antibiotic resistance

Genetic resistance to antibiotics is not the only trick bacteria use to resist eradication- they also have a second defence strategy known as persistence that can kick in.

6 Jan 2011

Water Street Healthcare announces acquisition of OraPharma from Johnson & Johnson

Water Street Healthcare Partners announced today that it has acquired OraPharma, Inc. from Johnson & Johnson. Water Street, a strategic private equity firm focused exclusively on health care, plans to build OraPharma into a leading specialty pharmaceutical company focused on dental and oral health care.

6 Jan 2011

Study: Antibiotics can provide long-lasting relief to patients with irritable bowel syndrome

A ground-breaking antibiotic therapy developed at Cedars-Sinai Medical Center is the first potential drug treatment to provide irritable bowel syndrome patients with long-lasting relief of their symptoms even after they stop taking the medication, according to a study published in the Jan. 6 issue of the New England Journal of Medicine.

6 Jan 2011

EUSA receives FDA Priority Review status for ERWINAZE BLA

EUSA Pharma, a transatlantic specialty pharmaceutical company focused on oncology, oncology supportive care and critical care, today announced that its Biologics License Application for ERWINAZE(R) has been accepted for filing and awarded Priority Review status by the U.S. Food and Drug Administration.

5 Jan 2011

Antibiotic News and Research

Further Reading

Researchers discover nitroxoline can reduce human breast, bladder cancer cell growth

Legionnaires’ disease scare in Bali: Australian tourists warned

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

PROLOR and Yeda enter definitive license agreement for Reversible PEGylation technology

Vaccine to prevent MRSA infections after bone and joint surgery

Antibiotics with blood pressure medications may cause hypotension

Antibiotic treatment may be sufficient to overcome River Blindness

Antibiotics for ear infection in kids better than watchful waiting: Study

Private rooms in the ICU help reduce hospital infections

Rib-X raises $20M to support development of broad spectrum antibiotics pipeline

Predator microbes may work against antibiotic resistant disease-causing bacteria: Study

Obama administration sides with drug companies in pricing lawsuit; Supreme Court agrees to hear case regarding use of prescription drug data

Targeted Genetics acquires Biocontrol

IDSA releases MRSA treatment guidelines

Studies show XIFAXAN 550 mg tablets demonstrate significant relief of global IBS symptoms

Columbia research team identifies bacteria may play a key role in atherosclerosis

Bacteria adopt defence strategy to promote antibiotic resistance

Water Street Healthcare announces acquisition of OraPharma from Johnson & Johnson

Study: Antibiotics can provide long-lasting relief to patients with irritable bowel syndrome

EUSA receives FDA Priority Review status for ERWINAZE BLA

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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