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Scientists develop safer CAR T-cell strategy for treating lymphomas

In the treatment of aggressive lymphomas and blood cancer (leukaemia), so-called chimeric antigen receptor T cells (CAR T cells) are increasingly being used.

9 Feb 2024

Breakthrough technique unveils secrets of "backtracking" in gene regulation

A technique can determine for the first time how frequently, and exactly where, a molecular event called "backtracking" occurs throughout the genetic material (genome) of any species, a new study shows.

9 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

Fungicide resistance: A global threat to human, animal, and plant health

Fungi can cause disease in both humans, animals, and plants. Every year, 1.5 million people die from fungal infections, and fungal attacks in food crops threaten food production.

9 Feb 2024

Machine learning tool reads brain scans for early signs of psychosis

The onset of psychosis can be predicted before it occurs, using a machine-learning tool which can classify MRI brain scans into those who are healthy and those at risk of a psychotic episode.

8 Feb 2024

Decoding the differences between two vital RNA transport complexes

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

8 Feb 2024

Artificial tears linked to drug-resistant bacteria outbreak, CDC finds

CDC scientists trace a multistate outbreak of highly drug-resistant Pseudomonas aeruginosa to a specific brand of over-the-counter artificial tears, underscoring the need for stricter regulation of medical products.

8 Feb 2024

Multi-level network analysis provides integrated view of multiple sclerosis

International research led by the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, in collaboration with Hospital del Mar, Hospital Clínic, Charité - Medical University of Berlin, and the universities of Oslo and Genoa, has developed a computational biology tool, based on multi-level network analysis, to achieve an integrated vision of multiple sclerosis.

8 Feb 2024

Never-before-documented genetic disorder causes rare lung disease

The macrophage is one of the body's most important inhabitants. Meaning "big eater" in Greek, this immune cell consumes and digests problematic elements from microbes and cancer cells to dust and debris.

8 Feb 2024

Mitochondrial misfire sparks inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA - a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy.

8 Feb 2024

Study advances search for a blood test to identify disease-associated changes in the brain

Researchers in a Johns Hopkins Children's Center-led study that used genetic material from human blood and lab-grown brain cells say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.

8 Feb 2024

Parental traits offer new clues to predicting neurodevelopmental disorders in children

Predicting the trajectory of neurodevelopmental and psychiatric disorders like autism or schizophrenia is difficult because they can be influenced by many different genetic and environmental factors.

8 Feb 2024

The relationship between psychiatric disorders and known genetic risks of dementia

Researchers investigated how pre-dementia psychiatric diagnoses relate to well-recognized genetic risk factors for dementia in a large longitudinal population-based cohort—the United Kingdom Biobank (UKB).

8 Feb 2024

Study suggests there may be specific pathways to adolescent depression that begin in the womb

Researchers investigated the relationship between prenatal maternal inflammation (PNMI) and depressive symptoms in their adolescent offspring.

8 Feb 2024

Study finds gut health key to combating skin diseases, eyes probiotics as potential treatment

Researchers review the significant impact of gut microbiome dysbiosis on skin diseases, suggesting probiotics could offer a new treatment path.

7 Feb 2024

New treatment target found for CDKL5 deficiency disorder

Scientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.

7 Feb 2024

Metal pollution contributes to reduced female fertility, with Zinc as a notable exception

Study finds certain metals, especially Copper and Chromium, adversely affect female fertility, while Zinc shows a protective effect, highlighting potential environmental factors in global fertility decline.

7 Feb 2024

New study sheds light on sex differences in allergic airway inflammation

Researchers explored how sex hormones and chromosomes influence allergic inflammation and gene expression in four-core genotype (FCG) mice exposed to house dust mites (HDMs).

7 Feb 2024

From stories to science: How listening together unveils parent-child brain signatures

Shared neural fingerprints between parents and their children while listening to stories.

7 Feb 2024

What natural compounds can help you manage your rosacea?

Researchers reviewed existing data on rosacea management using botanicals.

7 Feb 2024

Genetic News and Research

Scientists develop safer CAR T-cell strategy for treating lymphomas

Breakthrough technique unveils secrets of "backtracking" in gene regulation

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Fungicide resistance: A global threat to human, animal, and plant health

Machine learning tool reads brain scans for early signs of psychosis

Decoding the differences between two vital RNA transport complexes

Artificial tears linked to drug-resistant bacteria outbreak, CDC finds

Multi-level network analysis provides integrated view of multiple sclerosis

Never-before-documented genetic disorder causes rare lung disease

Mitochondrial misfire sparks inflammation

Study advances search for a blood test to identify disease-associated changes in the brain

Parental traits offer new clues to predicting neurodevelopmental disorders in children

The relationship between psychiatric disorders and known genetic risks of dementia

Study suggests there may be specific pathways to adolescent depression that begin in the womb

Study finds gut health key to combating skin diseases, eyes probiotics as potential treatment

New treatment target found for CDKL5 deficiency disorder

Metal pollution contributes to reduced female fertility, with Zinc as a notable exception

New study sheds light on sex differences in allergic airway inflammation

From stories to science: How listening together unveils parent-child brain signatures

What natural compounds can help you manage your rosacea?

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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