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Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Nearly every cell in the human body has one or more protrusive structures called cilia or flagella.

7 Dec 2016

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

Two genetic mutations known to play a role in many solid cancers might also help explain why a subset of acute myeloid leukemia (AML) patients develop the disease, according to new research from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

7 Dec 2016

TSRI scientists reveal how vision-loss treatment may leave the eyes, kidneys vulnerable to cellular damage

A common class of drugs for vision loss may actually add to the problem in some patients, according to new research co-led by scientists at The Scripps Research Institute (TSRI).

7 Dec 2016

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Throughout evolutionary history, there have been genetic elements that have duplicated - giving rise to genes with different functions.

7 Dec 2016

Scientists discover how motors maneuver cells' intricate roadway system

Much like motors power our cars, they also ensure that proteins get to the right place in our cells, and a wide variety of diseases - from cancer to heart problems - can result when they don't.

7 Dec 2016

VIB scientists reveal how NLRP2 protein plays key role in early embryogenesis and fertility

Led by Prof. Mohamed Lamkanfi (VIB-Ghent University), researchers have demonstrated in animal models that a protein called NLRP2 plays an important role in early embryogenesis, the process of cell division in fertilized eggs that occurs before they implant into the lining of the uterus.

6 Dec 2016

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment.

6 Dec 2016

Research findings point to inherited genetic basis of ALL risk in children

A late-breaking abstract being presented today during the 58th American Society of Hematology Annual Meeting and Exposition in San Diego identifies inherited genetic mutations in the gene IKZF1 that confer a higher likelihood of developing pediatric acute lymphocytic leukemia (ALL).

6 Dec 2016

Tufts scientists discover reason for incidence of genetic error that causes many disorders

Tufts University researchers have discovered a possible explanation for the occurrence of a genetic error that causes over a dozen neuromuscular and neurodegenerative disorders, including Huntington's disease, myotonic dystrophy and forms of spinocerebellar ataxia.

6 Dec 2016

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Autism spectrum disorder is caused by a variety of factors, both genetic and environmental.

5 Dec 2016

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

A promising new combination therapy for a particularly aggressive form of breast cancer has been identified by Weizmann Institute scientists, as was recently reported in Cancer Research.

5 Dec 2016

Simple, coordinated approach can improve chances of survival for high-risk AML patients

New research shows that quickly identifying patients with high-risk acute myeloid leukemia (AML), and speeding the process to find them a stem cell donor and performing the transplant earlier, can significantly improve their chances of surviving for at least two years after diagnosis without a relapse.

5 Dec 2016

New drug treatment can override genetic fault that causes choroideremia

Researchers with funding from Fight for Sight have demonstrated that a new drug treatment for cystic fibrosis and Duchenne muscular dystrophy can override a genetic fault that causes choroideremia – a severe blinding disorder.

5 Dec 2016

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs).

4 Dec 2016

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report.

2 Dec 2016

New FDA-approved drug helps patients fight against late-stage lung cancer

A new drug has been approved by the FDA in the fight against lung cancer. Tecentriq is being used by patients like Cornelius Bresnan, who had late-stage cancer.

2 Dec 2016

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

The emergence of new therapies that treat the causes of cystic fibrosis are creating an imperative for more accurate variant analysis.

2 Dec 2016

Scientists discover unique genomic changes integral to testicular cancer development

Researchers led by scientists at Dana-Farber Cancer Institute say they have identified unique genomic changes that may be integral to testicular cancer development and explain why the great majority are highly curable with chemotherapy - unlike most solid tumors.

1 Dec 2016

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN.

1 Dec 2016

Mutation News and Research

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Enzyme that cleaves beta carotene may control testosterone levels

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

TSRI scientists reveal how vision-loss treatment may leave the eyes, kidneys vulnerable to cellular damage

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Scientists discover how motors maneuver cells' intricate roadway system

VIB scientists reveal how NLRP2 protein plays key role in early embryogenesis and fertility

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Research findings point to inherited genetic basis of ALL risk in children

Tufts scientists discover reason for incidence of genetic error that causes many disorders

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

Simple, coordinated approach can improve chances of survival for high-risk AML patients

New drug treatment can override genetic fault that causes choroideremia

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

New FDA-approved drug helps patients fight against late-stage lung cancer

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

Scientists discover unique genomic changes integral to testicular cancer development

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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