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New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inherited disease for which there is no cure.

1 Dec 2016

New study finds genetic link between Parkinson's disease and cognitive decline

Although the hallmark symptoms of Parkinson's disease (PD) - such as involuntary shaking, slowness of movement and muscle rigidity - are related to movement, recent evidence has suggested that memory impairment plays an outsized role in diminished quality of life and the burden placed on caregivers.

1 Dec 2016

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods published (online) a comparative study of leading Protein-Protein Interaction (PPI) Networks.

1 Dec 2016

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations.

1 Dec 2016

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity.

30 Nov 2016

HD is myopathy as well as neurodegenerative disease, study suggests

Researchers have discovered that mice with Huntington's disease (HD) suffer defects in muscle maturation that may explain some symptoms of the disorder.

29 Nov 2016

Research provides new insight into how diseases that disconnect brain and body occur

A huge colony of receptors must be optimally positioned and functioning on our muscle cells for our brains to talk with our bodies so we can walk and breathe.

29 Nov 2016

Researchers find new way to target deadly virus and develop vaccines

Venezuelan equine encephalitis virus (VEEV) is an unforgiving killer of horses, donkeys and zebras, resulting in mortality as high as 80 percent of infected animals. It causes rapid, catastrophic swelling of the brain and spinal cord, leading to severe neurological symptoms and--in many cases--sudden death.

29 Nov 2016

Scientists develop easy-to-use software tool to detect important genetic mutations

Scientists have developed an easy-to-use software tool that can detect important genetic mutations that previously needed to be identified by a separate test.

29 Nov 2016

Recessive gene mutations could cause debilitating neurological disease in children

Researchers have linked a debilitating neurological disease in children to mutations in a gene that regulates neuronal development through control of protein movement within neuronal cells.

29 Nov 2016

Gene mutation appears to increase risk of Parkinson's disease in Caucasians

A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research from Iowa State University. The effect is particularly dramatic for people under age 50.

28 Nov 2016

New study finds link between memory mechanisms and resistance to epilepsy

A new study undertaken jointly by researchers from the Sagol Department of Neurobiology at the University of Haifa and European researchers, published in the journal Cerebral Cortex, exposes a new biological mechanism that, on the one hand, damages a very specific type of memory, but at the same time provides resistance to epilepsy.

25 Nov 2016

ASGCT seeks to educate public and policy-makers on fundamentals of gene editing

On Nov. 21, 2016, the American Society of Gene & Cell Therapy released Therapeutic Gene Editing: an ASGCT White Paper, intended to provide policy-makers, patient advocates, and the interested public with the necessary background information in anticipation of an upcoming consensus report on human gene editing from the National Academy of Sciences and National Academy of Medicine (NAS), expected to be released in early 2017.

24 Nov 2016

Cancer gene mutations can predict response to less intensive treatment in AML patients

Patients with the most lethal form of acute myeloid leukemia (AML) - based on genetic profiles of their cancers - typically survive for only four to six months after diagnosis, even with aggressive chemotherapy.

23 Nov 2016

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow.

23 Nov 2016

Researchers identify simple, inexpensive tool for assessing prognosis of pediatric brain tumors

A multi-institutional group of researchers, led by investigators at Children's Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive tool for assessing the prognosis of pediatric brain tumors called ependymomas.

23 Nov 2016

Mutation News and Research

New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

New study finds genetic link between Parkinson's disease and cognitive decline

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

HD is myopathy as well as neurodegenerative disease, study suggests

Research provides new insight into how diseases that disconnect brain and body occur

Researchers find new way to target deadly virus and develop vaccines

Scientists develop easy-to-use software tool to detect important genetic mutations

Recessive gene mutations could cause debilitating neurological disease in children

Gene mutation appears to increase risk of Parkinson's disease in Caucasians

New study finds link between memory mechanisms and resistance to epilepsy

ASGCT seeks to educate public and policy-makers on fundamentals of gene editing

Cancer gene mutations can predict response to less intensive treatment in AML patients

HSCI researchers use color tagging system to track development of blood stem cells

Researchers identify simple, inexpensive tool for assessing prognosis of pediatric brain tumors

IQWiG finds colorectal cancer drug combination has added benefit only for some patients

Study finds genomic regions with copy number variants linked to schizophrenia risk

Study offers genetic explanation why cancer occurs commonly in males than females

Titin gene mutations affect heart function in healthy individuals, study finds

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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