Sclerosis News and Research

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Targeting astrocytes slows progression of Lou Gehrig's disease

In what the researchers say could be promising news in the quest to find a therapy to slow the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, scientists at the University of California, San Diego (UCSD) School of Medicine have shown that targeting neuronal support cells called astrocytes sharply slows disease progression in mice.

4 Feb 2008

Unexpected protein-protein interaction suggests new ALS drug target

Discovery of an unexpected protein-protein interaction has led University of Iowa scientists and colleagues to identify a drug that slows the progression of Amyotrophic Lateral Sclerosis (ALS) in mice and nearly doubles the animals' lifespan.

25 Jan 2008

Brain molecule from endothelial cells may be a new target for treatment of multiple sclerosis

In the February issue of Nature Immunology, the team provides fresh answers concerning the role of novel adhesion molecules in the pathogenesis of MS, a chronic autoimmune disease of the nervous system that affects approximately 55,000 young adults in Canada.

23 Jan 2008

Current state of the art in glycoscience

Sugars were once credited with magical healing powers but are now seen like salt as an evil necessary in small doses but the cause of numerous diseases such as diabetes if taken in excess.

18 Jan 2008

Genetic differences may explain response to multiple sclerosis treatment

By comparing the DNA of patients with multiple sclerosis whose symptoms are reduced by interferon beta therapy to the DNA of those who continue to experience relapses, researchers may have identified important genetic differences between the two, according to an article posted online that will appear in the March 2008 print issue of Archives of Neurology.

16 Jan 2008

How asthma and allergy symptoms are triggered

In demonstrating that a group of calcium ion channels play a crucial role in triggering inflammatory responses, researchers at Beth Israel Deaconess Medical Center (BIDMC) have not only solved a longstanding molecular mystery regarding the onset of asthma and allergy symptoms, but have also provided a fundamental discovery regarding the functioning of mast cells.

15 Jan 2008

Researchers find new way to block destructive rush of immune cells

Researchers have found a way to selectively block the ability of white blood cells to "crawl" toward the sites of injury and infection when such mobility drives disease, according to a study published today in The Journal of Experimental Medicine.

15 Jan 2008

Genetic differences may help explain response to multiple sclerosis treatment

15 Jan 2008

FDA approves Tysabri to treat Crohn's disease

The U.S. Food and Drug Administration has approved Tysabri (natalizumab) for the treatment of moderate-to-severe Crohn's disease in patients with evidence of inflammation who have had an inadequate response to, or are unable to tolerate, conventional Crohn's disease therapies.

14 Jan 2008

New motor system impairment diagnosing tool

Researchers from the Universidad Politécnica de Madrid are developing a tool that will allow doctors to easily evaluate the degree and type of the tremors caused in the upper limbs by some neurological disorders.

14 Jan 2008

Seasonal flu levels trigger use of antiviral drugs

The Health Protection Agency has confirmed that the rate at which influenza viruses are now circulating in England has reached the point which triggers the use of antiviral drugs.

11 Jan 2008

Lymphangioleiomyomatosis - potential clues into the treatment and diagnosis

Studies published in the Jan. 10 edition of the New England Journal of Medicine (NEJM) are providing clues into the treatment and diagnosis of LAM, or lymphangioleiomyomatosis, a progressive and deadly lung disease that affects women in their childbearing years.

11 Jan 2008

Chemical first found on Easter Island could treat tuberous sclerosis

A new study has shown promising results in fighting a severe genetic disorder which can create tumours throughout the body.

11 Jan 2008

The drug sirolimus shrinks tumors, improves lung function

The drug sirolimus, normally used to help transplant patients fight organ rejection, may eventually be used as a less invasive treatment for a tumor called angiomyolipomata in patients with who would otherwise face surgery.

10 Jan 2008

New Sleep and Breathing Disorders Center at UT Southwestern

UT Southwestern Medical Center has assembled a comprehensive team of experts in pulmonary medicine, neurology, psychiatry, pediatrics, otolaryngology, surgery and rehabilitation medicine to work together in a new Sleep and Breathing Disorders Center.

10 Jan 2008

Rockefeller University funds clinical, translational pilot studies

The Rockefeller University Center for Clinical and Translational Science (CCTS) has announced the recipients of its 2008 Pilot Project grants.

8 Jan 2008

Low blood levels of vitamin D linked to heart attacks and strokes

According to new research people who have low levels of vitamin D in their blood are at an increased risk for heart attack, heart failure and stroke.

7 Jan 2008

Growing burden of arthritis in the U.S.

Arthritis is the most common cause of disability in the United States. Over the next 25 years as the Baby Boom generation continues to age, the toll of this disease will escalate.

3 Jan 2008

The blood-brain barrier: A misunderstood key to finding life-saving cures to brain disease

An international team of scientists that includes a Saint Louis University researcher suggest several strategies to propel research for treatments of brain diseases that include multiple sclerosis, Alzheimer's disease, obesity and stroke in the January issue of the Lancet Neurology.

20 Dec 2007

Addition of antibiotics to MS therapy could slow down progression of the disease

Researchers from Louisiana State University in the U.S. are suggesting that the addition of antibiotics to standard drug therapy for multiple sclerosis, may slow down the progress of the disease.

19 Dec 2007