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Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.

25 Apr 2024

Yeast study reveals evolutionary history of iron uptake mechanisms

Competition and cooperation are fundamental forces that govern the evolutionary and ecological dynamics among species.

25 Apr 2024

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases.

25 Apr 2024

Study finds rise in volumes and survival after hematopoietic cell transplants among racial/ethnic minorities

The volume of hematopoietic cell transplants rose among all racial/ethnic groups, but grew faster among African Americans and Hispanics compared with Non-Hispanic white individuals, mirroring changes in population growth rates.

25 Apr 2024

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level.

25 Apr 2024

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

The Covid-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, which collects all the genetic data of a given microorganism.

25 Apr 2024

DELiVR's virtual reality training speeds up cell detection in complex brain datasets

Efficient neuronal activity detection in brain imaging.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurately mimic the development of colorectal tumors, offering a powerful new tool for studying and testing treatments for the disease.

24 Apr 2024

Paclitaxel treatment found to directly promote HBV replication and transcription

Hepatitis B virus (HBV) reactivation is commonly observed in individuals with chronic HBV infection undergoing antineoplastic drug therapy.

24 Apr 2024

Giant virus takes down deadly brain parasite

The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses that infect this harmful microbe.

24 Apr 2024

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments.

24 Apr 2024

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells – the cells that have a specialized function, like skin and muscle cells – they remain elusive in the first cells of our bodies, the embryonic cells.

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

B Cell News and Research

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

Yeast study reveals evolutionary history of iron uptake mechanisms

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

Study finds rise in volumes and survival after hematopoietic cell transplants among racial/ethnic minorities

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

DELiVR's virtual reality training speeds up cell detection in complex brain datasets

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

Prostaglandin E2: The culprit behind tumor immune evasion

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

Paclitaxel treatment found to directly promote HBV replication and transcription

Giant virus takes down deadly brain parasite

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

Study highlights nutrition therapy's potential to manage gestational diabetes effectively

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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