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Multidisciplinary medical team needed to provide care for pregnant women with lupus, study says

A study that includes researchers at Hospital for Special Surgery underscores the importance of a multidisciplinary medical team to counsel and provide care for women with systemic lupus erythematosus, the most common form of lupus, who become pregnant.

2 Jun 2022

Cancer patients have a greater risk for developing diabetes, study says

Cancer patients are at a greater risk for developing diabetes, according to a new study by the Steno Diabetes Center Copenhagen, Rigshospitalet, and the University of Copenhagen.

2 Jun 2022

Immune modulator drugs improved clinical status, reduced deaths among patients hospitalized with COVID-19

A large randomized, placebo-controlled clinical trial led by the National Institutes of Health shows that treating adults hospitalized with COVID-19 with infliximab or abatacept - drugs widely used to treat certain autoimmune diseases - did not significantly shorten time to recovery but did substantially improve clinical status and reduce deaths.

2 Jun 2022

Mitral annulus calcification is a predictor of mortality and a marker of valvular, cardiovascular disease

A retrospective review of more than 24,000 patients who underwent an EKG at Mayo Clinic finds that nearly one-quarter of the patients had mitral annulus calcification, a chronic degeneration of tissue at the base of the heart's mitral valve.

2 Jun 2022

The effect of corticosteroids on mortality in hospitalized COVID-19 patients

Researchers assessed the impact of modern causal inference methods in estimating the effect of corticosteroids against COVID-19-related mortality.

2 Jun 2022

The effectiveness of nirmatrelvir therapy for preventing mortality and hospitalizations due to COVID-19 in high-risk patients during the Omicron surge

Researchers evaluated how effective nirmatrelvir is in preventing COVID-19-associated death and hospitalization in high-risk patients.

2 Jun 2022

Prenatal exposure to antiseizure drugs associated with risk of autism and intellectual disability

Women with epilepsy often need medication to prevent seizures during pregnancy. Previous studies have found an association between exposure to the antiseizure medication valproate during pregnancy and risk of autism and low IQ in the offspring.

2 Jun 2022

Newer class of antidiabetic drugs reduced risk of hospitalization for heart failure

In cardiovascular outcome trials among adults with type 2 diabetes (T2D), sodium-glucose co-transporter 2 inhibitors (SGLT-2i) have shown therapeutic promise, including reduced risk of hospitalization for heart failure compared to placebo.

1 Jun 2022

Genetically modified herpes virus can be used in the fight against cancer

Viruses can make animals and humans sick - or healthy: Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have succeeded in genetically modifying the herpes simplex virus type 1, which triggers painful cold sores, in such a way that it can be used in the fight against cancer in the future.

1 Jun 2022

Study untangles the link between malnutrition and sarcopenia in end-stage kidney disease patients

End-stage kidney disease patients undergoing maintenance hemodialysis (MHD) often struggle with malnutrition and sarcopenia, a form of musculoskeletal atrophy that amplifies mortality.

1 Jun 2022

Deadly drug overdose rates among Black people more than doubles in Kentucky

The rate of deadly drug overdoses among Black people in Kentucky more than doubled from 2016 to 2020, according to a new analysis by University of Kentucky researchers.

1 Jun 2022

The impact of SARS-CoV-2 linkage on outcomes in hospitalized children with PIMS across Canada

Researchers analyze the clinical effects and implications of SARS-CoV-2 infection in children who were hospitalized due to MIS-C.

1 Jun 2022

Early diagnosis and intervention could prevent mortality from alcohol-related liver disease

Patients dying of alcohol-related liver disease had frequent interactions with secondary care services prior to their death, and a new study has found that these opportunities to address their high-risk drinking behavior could have been missed.

1 Jun 2022

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

A recent article illustrated the structural and biochemical characteristics of the processing of SARS-CoV-2 polyproteins by Mpro.

1 Jun 2022

COVID-19 pandemic increased the number of cancer-related mortality in the U.S., study shows

According to a new study led by researchers at the American Cancer Society (ACS), the COVID-19 pandemic increased the number of cancer-related deaths by 3.2% in the United States from 2019- 2020.

31 May 2022

U.S. health and mortality continue to rank poorly compared to peer countries

Health and mortality in the U.S. continue to rank poorly compared to peer nations, and a new supplemental issue to The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences titled "Why Does Health in the U.S. Continue to Lag Behind?" features papers that analyze the reasons for the downward trends.

31 May 2022

MGH scientists develop a data-driven simulation model to address the rampant opioid crisis

The effectiveness of tixagevimab/cilgavimab for prevention of SARS-CoV-2 infection and severe disease among immunocompromised patients

A recent article assessed the potency of tixagevimab/cilgavimab in averting SARS-CoV-2 infection in vaccinated immunocompromised people.

31 May 2022

Mortality News and Research

Multidisciplinary medical team needed to provide care for pregnant women with lupus, study says

Cancer patients have a greater risk for developing diabetes, study says

Immune modulator drugs improved clinical status, reduced deaths among patients hospitalized with COVID-19

Mitral annulus calcification is a predictor of mortality and a marker of valvular, cardiovascular disease

The effect of corticosteroids on mortality in hospitalized COVID-19 patients

The effectiveness of nirmatrelvir therapy for preventing mortality and hospitalizations due to COVID-19 in high-risk patients during the Omicron surge

Prenatal exposure to antiseizure drugs associated with risk of autism and intellectual disability

Newer class of antidiabetic drugs reduced risk of hospitalization for heart failure

Genetically modified herpes virus can be used in the fight against cancer

Study untangles the link between malnutrition and sarcopenia in end-stage kidney disease patients

Deadly drug overdose rates among Black people more than doubles in Kentucky

The impact of SARS-CoV-2 linkage on outcomes in hospitalized children with PIMS across Canada

Early diagnosis and intervention could prevent mortality from alcohol-related liver disease

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

COVID-19 pandemic increased the number of cancer-related mortality in the U.S., study shows

U.S. health and mortality continue to rank poorly compared to peer countries

MGH scientists develop a data-driven simulation model to address the rampant opioid crisis

Study: Cardiovascular mortality risk differs among cancer survivors by race/ethnicity and cancer types

New androgen biosynthesis inhibitor drug for prostate cancer shows mixed results

The effectiveness of tixagevimab/cilgavimab for prevention of SARS-CoV-2 infection and severe disease among immunocompromised patients

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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