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Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

A recent study published in the journal Cellular & Molecular Immunology shows that a new A.30 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can evade vaccine-induced antibodies and might spread outside the lungs extraordinarily well, with important implications for our public health response.

1 Nov 2021

The impact of SARS-CoV-2 variants on the COVID-19 epidemic in South Africa

A new study explores the role of new SARS-CoV-2 variants in sustaining the pandemic in South Africa.

31 Oct 2021

New Canadian serology solution for SARS-CoV-2 infections and vaccination

A new study developed a “Made-in-Canada” solution for enabling scalable and reproducible SARS-CoV-2 serology.

31 Oct 2021

The ability of natural flavonoids to inhibit SARS-CoV-2

A recent systematic review discusses naturally occurring flavonoids as a promising antiviral alternative against SARS-CoV-2.

31 Oct 2021

Protein pairs assemble based on their complementary shapes

Proteins bind to one another through a complex mix of chemical interactions. What if some proteins bind due to their shapes, a much simpler process? To answer this question, researchers used Summit, the nation's fastest supercomputer, to model lock-and-key interactions.

30 Oct 2021

New evidence that SARS-CoV-2 virus can infect the inner ear

Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

29 Oct 2021

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

Postmenopausal women have increased risk of non-alcoholic fatty liver disease due to loss of estrogen from metabolic changes. A high-fat diet further exacerbates the disease, which can progress to cirrhosis and liver failure.

29 Oct 2021

How long does natural or vaccine-induced immunity to COVID last?

Researchers present a comprehensive assessment on SARS-CoV-2 induced immunity.

28 Oct 2021

A novel approach to improve the stability of Remdesivir

A recent study discusses a novel method to enhance the stability of Remdesivir.

28 Oct 2021

Structure of human-infecting canine coronavirus HuPn-2018 spike glycoprotein

As CCoV-HuPn-2018 has been recently isolated in a child's respiratory swab, researchers from the University Of Washington have been examining the structure of the virus.

28 Oct 2021

Study finds one mRNA vaccine dose after SARS-CoV-2 infection produces highest neutralizing antibody titers

Researchers investigated the neutralizing antibody response that different mRNA vaccines induce in both previously convalescent and SARS-CoV-2 naïve individuals.

28 Oct 2021

Panel of broadly neutralizing SARS-CoV-2 nanobodies for immune assay application

In this study, a team of researchers from Japanese institutions provide a panel of broadly neutralizing nanobodies that detect four VOCs.

28 Oct 2021

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

A new study identifies a potent SARS-CoV-2 antiviral, Pheophorbide a (PheoA), which is a compound derived from the plant Marchantia polymorpha L.

27 Oct 2021

COVID-19 and subacute neuropsychiatric symptoms in adolescents

A new paper discusses neurologic symptoms in children with COVID-19.

27 Oct 2021

The difference in the dynamics of SARS-COV-2 variants

A new study provides a detailed description of the varying interactions between SARS-CoV-2 and the host cell ACE-2 receptor.

27 Oct 2021

Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

Researchers emphasize that an effective vaccine should induce mucosal immunity and prevent the nasal entry of SARS-CoV-2.

27 Oct 2021

A study on the SARS-CoV-2 B.1.620 lineage

In a recently published Nature Communications study, the authors describe the B.1.620 lineage discovered in Lithuania.

27 Oct 2021

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

New research shows that testosterone promotes melanoma proliferation by activating a newly recognized nonclassical testosterone receptor in melanoma cells called ZIP9 (encoded by the SLC39A9 gene), a zinc transporter that is not intentionally targeted by any available therapeutics but is widely expressed in human melanoma.

27 Oct 2021

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination amongst healthcare workers

The heterologous ChAd/BNT combination confers better protection against SARS-CoV-2 infection than the homologous BNT/BNT combination in a real-world observational study of healthcare workers.

27 Oct 2021

Study of SARS-CoV-2 antibody seroprevalence among domestic cats

Researchers from the University of Veterinary Medicine Hannover have been investigating the spread of the disease in domestic cats in Europe.

27 Oct 2021

Receptor News and Research

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

The impact of SARS-CoV-2 variants on the COVID-19 epidemic in South Africa

New Canadian serology solution for SARS-CoV-2 infections and vaccination

The ability of natural flavonoids to inhibit SARS-CoV-2

Protein pairs assemble based on their complementary shapes

New evidence that SARS-CoV-2 virus can infect the inner ear

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

How long does natural or vaccine-induced immunity to COVID last?

A novel approach to improve the stability of Remdesivir

Structure of human-infecting canine coronavirus HuPn-2018 spike glycoprotein

Study finds one mRNA vaccine dose after SARS-CoV-2 infection produces highest neutralizing antibody titers

Panel of broadly neutralizing SARS-CoV-2 nanobodies for immune assay application

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

COVID-19 and subacute neuropsychiatric symptoms in adolescents

The difference in the dynamics of SARS-COV-2 variants

Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

A study on the SARS-CoV-2 B.1.620 lineage

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination amongst healthcare workers

Study of SARS-CoV-2 antibody seroprevalence among domestic cats

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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