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Santaris Pharma, miRagen collaborate to develop microRNA-targeted medicines for cardiovascular disease

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies and miRagen Therapeutics, Inc., a biopharmaceutical company focused on developing innovative microRNA-based therapeutics for cardiovascular and muscle disease, announced today that they have formed a strategic alliance to develop microRNA-targeted medicines for the treatment of cardiovascular disease.

23 Jun 2010

imec researchers demonstrate biosensors that detect extremely low concentrations of disease markers

Researchers at the nanotechnology research centre imec have demonstrated biosensors based on novel nanostructure geometries that increase the sensitivity and allow to detect extremely low concentrations of specific disease markers. This paves the way to early diagnostics of for example cancer by detecting low densities of cancer markers in human blood samples.

23 Jun 2010

US physicians concerned about health risk to patients from heat-damaged medicinal products

In a recent Harris Interactive survey of US physicians about the proper storage and handling of temperature-sensitive medicines prescribed and administered to patients, physicians reported being concerned about this issue, and the overwhelming majority are concerned that heat-damaged products resulting from cumulative exposure to temperatures outside the specified temperature range pose a health risk to patients. The announcement of the study findings was made today by Temptime Corporation.

23 Jun 2010

Folic acid and vitamin B12 lower homocysteine levels in patients who experience heart attack: JAMA

Patients who had experienced a heart attack and lowered their blood homocysteine levels with folic acid and vitamin B12 supplementation did not have an associated lower risk of heart attack, coronary death or stroke, according to a study in the June 23/30 issue of JAMA. However, the researchers did find that folic acid supplementation did not increase the risk of cancer, which has been speculated.

23 Jun 2010

Endocrine Society presents Scientific Statement on menopausal hormone therapy at ENDO 2010

The Endocrine Society presented its Scientific Statement on menopausal hormone therapy Monday in San Diego, Calif. at ENDO 2010: The 92nd Annual Meeting & Expo.

23 Jun 2010

Diet with high fructose, trans fats lead to fatty liver disease with scar tissue

Scientists at Cincinnati Children's Hospital Medical Center have discovered that a diet with high levels of fructose - levels equivalent to that in high fructose corn syrup - and of trans fats not only increases obesity, but also leads to significant fatty liver disease with scar tissue.

23 Jun 2010

Researchers treat acute kidney injury using cells genetically reprogrammed to produce protein

A protein whose primary role is in the embryonic development of kidneys may play a future role in treating kidney failure. Indiana University School of Medicine researchers have successfully treated acute kidney injury in laboratory experiments using cells that were genetically reprogrammed to produce the protein. The research suggests there could be a potential future treatment using such cells delivered intravenously instead of surgically.

23 Jun 2010

SPS receives $2.2M NHLBI grant to commercialize steerable cardiac mapping, ablation catheter technology

Strategic Polymer Sciences, Inc. (SPS), an innovator in advanced medical devices based on its proprietary electroactive polymer (EAP) technology, today announced it has received a $2.2 million grant from the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH). The SPS grant is one of only ten awarded nationwide by the NIH under a Recovery Act Limited Competition called The Biomedical Research, Development, and Growth to Spur the Acceleration of New Technologies (BRDG-SPAN) Pilot Program.

23 Jun 2010

Excessive, uncontrolled vascular growth leads to development of cavernomas: Researchers

Benign vascular malformations known as cavernomas can occur in many tissues of the body. These abnormalities are characterized by enlarged, instable and unstructured blood vessels. Cavernomas of medical relevance are primarily those of the brain, which develop approximately in one out of two hundred people. In the brain, such growths often remain unnoticed and are typically found by chance in MRI scans. If they grow larger, they often cause unspecific symptoms such as headaches or dizziness.

23 Jun 2010

Preschool children with tooth decay more likely to be obese: Study

Preschool children with tooth decay may be more likely to be overweight or obese than the general population and, regardless of weight, are more likely to consume too many calories, a new study indicates. The results will be presented Saturday at The Endocrine Society's 92nd Annual Meeting in San Diego.

23 Jun 2010

Karolinska Institutet receives SEK 100M grant for Wallenberg Institute for Regenerative Medicine

Karolinska Institutet has received a grant of SEK 100 million from the Knut and Alice Wallenberg Foundation for a regenerative medicine research centre - the Wallenberg Institute for Regenerative Medicine (WIRM). This funding will give Karolinska Institutet a unique opportunity to concentrate on new and pioneering research, with a special focus on the blood system.

23 Jun 2010

High blood sugar in mother during pregnancy leads to reduced insulin sensitivity in children

Children of mothers whose blood glucose (sugar) was high during pregnancy are more likely to have low insulin sensitivity—a risk factor for type 2 diabetes—even after taking into consideration the children's body weight, a new study shows. The results will be presented Tuesday at The Endocrine Society's 92nd Annual Meeting in San Diego.

23 Jun 2010

Student receives two-year $46,000 fellowship to research on a parasite that causes Chagas' disease

Michelle Oppenheimer of Charlotte, N.C., a Ph.D. student in biochemistry in the College of Agriculture and Life Sciences at Virginia Tech, has received a two-year $46,000 fellowship from the American Heart Association to advance her research on a parasite that causes Chagas' disease, which can lead to swelling and inflammation of the heart.

23 Jun 2010

Resveratrol found in red wine neutralizes toxicity of proteins related to Alzheimer's disease: Research

An organic compound found in red wine - resveratrol - has the ability to neutralize the toxic effects of proteins linked to Alzheimer's disease, according to research led by Rensselaer Professor Peter M. Tessier. The findings, published in the May 28 edition of the Journal of Biological Chemistry, are a step toward understanding the large-scale death of brain cells seen in certain neurodegenerative diseases.

23 Jun 2010

UAB receives $1.47M NHLBI grant to study red blood cell lesion

Researchers in the University of Alabama at Birmingham (UAB) departments of Pathology, Microbiology and Surgery have received a $1.47 million grant from the National Heart, Lung, and Blood Institute (NHLBI) to study so-called red blood cell lesion, a term given to the potentially harmful changes in red blood cells that have been stored for longer times after collection.

23 Jun 2010

Nymox reports positive new results from NX02-0014 follow-up study of NX-1207 for BPH

Nymox Pharmaceutical Corporation is pleased to report positive new results from the 48-60 month follow-up study of patients treated with NX-1207 in Study NX02-0014. The initial study, completed in the U.S. in 2006, reached statistical significance in Intent-to-Treat Primary Efficacy outcomes at 90 days post-treatment with NX-1207 2.5 mg.

23 Jun 2010

Scientists discover weakness of human louse

Scientists have discovered the human louse's Achilles' heel which could lead to new treatments to rid us of body and head lice infestations.

23 Jun 2010

Weight gain after age of 50 is associated with increased risk of diabetes after 65 years

For individuals 65 years of age and older, obesity, excess body fat around the waist and gaining weight after the age of 50 are associated with an increased risk of diabetes, according to a study in the June 23/30 issue of JAMA.

23 Jun 2010

Walmart, Eli Lilly to provide affordable insulin option for people with diabetes

Walmart and Eli Lilly and Company announced today they're teaming up to provide an affordable insulin option for people with diabetes.

23 Jun 2010

Mice treated with XOMA 052 experiences improvement in measures associated with diabetes: Endocrinology

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced the publication of data from a mouse model of diet-induced obesity in the June, 2010 edition of the journal Endocrinology. The data showed that mice treated with XOMA 052 both prophylactically and therapeutically experienced improvement in measures associated with diabetes and cardiovascular disease including reduction in glycosylated hemoglobin levels, improvement in glucose control, improved beta-cell survival and function, and a reduction in total cholesterol without reduction in high density lipoprotein.

23 Jun 2010

Blood News and Research

Santaris Pharma, miRagen collaborate to develop microRNA-targeted medicines for cardiovascular disease

imec researchers demonstrate biosensors that detect extremely low concentrations of disease markers

US physicians concerned about health risk to patients from heat-damaged medicinal products

Folic acid and vitamin B12 lower homocysteine levels in patients who experience heart attack: JAMA

Endocrine Society presents Scientific Statement on menopausal hormone therapy at ENDO 2010

Diet with high fructose, trans fats lead to fatty liver disease with scar tissue

Researchers treat acute kidney injury using cells genetically reprogrammed to produce protein

SPS receives $2.2M NHLBI grant to commercialize steerable cardiac mapping, ablation catheter technology

Excessive, uncontrolled vascular growth leads to development of cavernomas: Researchers

Preschool children with tooth decay more likely to be obese: Study

Karolinska Institutet receives SEK 100M grant for Wallenberg Institute for Regenerative Medicine

High blood sugar in mother during pregnancy leads to reduced insulin sensitivity in children

Student receives two-year $46,000 fellowship to research on a parasite that causes Chagas' disease

Resveratrol found in red wine neutralizes toxicity of proteins related to Alzheimer's disease: Research

UAB receives $1.47M NHLBI grant to study red blood cell lesion

Nymox reports positive new results from NX02-0014 follow-up study of NX-1207 for BPH

Scientists discover weakness of human louse

Weight gain after age of 50 is associated with increased risk of diabetes after 65 years

Walmart, Eli Lilly to provide affordable insulin option for people with diabetes

Mice treated with XOMA 052 experiences improvement in measures associated with diabetes: Endocrinology

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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