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People with very irregular sleep patterns may have higher dementia risk

People who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns, according to new research published in the December 13, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Dec 2023

Protective genetic variant shields Black Americans from kidney disease risk

Many Black Americans who are thought to have a high risk of developing kidney disease possess a protective genetic variant that nullifies the extra risk, a new study from Columbia researchers has found.

12 Dec 2023

OHSU study sheds light on ubiquitin modification during bacterial infection

New research from Oregon Health & Science University could one day lead to therapies that prevent or treat diseases and infections tied to a protein that's found in all human cells.

12 Dec 2023

UK Biobank data shows dose-dependent link between smoking and brain shrinkage

Smoking shrinks the brain, according to a study by researchers at Washington University School of Medicine in St. Louis.

12 Dec 2023

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Published in The Lancet's eBioMedicine, 76 healthy adults from Melbourne, aged 18 to 64 who were previously vaccinated with licensed SARS-CoV-2 vaccines, were randomized to receive a fourth dose of a novel protein vaccine, mRNA vaccine or placebo.

12 Dec 2023

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

Using a "liquid biopsy" to study genetic material from tumors shed into the bloodstream together with immune cells could help clinicians predict which patients with advanced lung cancers are responding to immunotherapies and which patients may develop immune-related side effects several months later, according to research directed by investigators at the Johns Hopkins Kimmel Cancer Center, the Bloomberg~Kimmel Institute for Cancer Immunotherapy and Allegheny Health Network Cancer Institute in Pittsburgh.

12 Dec 2023

UVA atlas unveils cellular blueprint of atherosclerosis

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

12 Dec 2023

Bottlenecks in Nucleic Acid Extraction: A Multi-Industrial approach with HiMedia Labs

An interview with Dr. Rajas Warke, Director of Molecular Biology and virology at HiMedia Labs.

From Himedia Laboratories Private Limited 12 Dec 2023

New optimized vaccine approach targets Hepatitis C virus variability

A method to design vaccines for highly variable viruses like the hepatitis C virus.

12 Dec 2023

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Researchers evaluated the effectiveness of adeno-associated virus (AAV)-mediated Plakophilin 2 (PKP2) delivery in treating arrhythmogenic cardiomyopathy (ACM).

12 Dec 2023

Coffee and caffeine boost metabolism and enhance exercise performance, study finds

Study reveals that coffee and caffeine enhance metabolism and exercise performance, showing varied effects on heart rate, energy expenditure, fat loss, and insulin sensitivity, with implications for athletes and general health.

11 Dec 2023

Study reveals new mechanism by which rotavirus induces diarrhea

Rotavirus causes gastroenteritis, a condition that includes diarrhea, deficient nutrient absorption and weight loss. Severe cases result in approximately 128,000 deaths annually in infants and children worldwide.

11 Dec 2023

Ketogenic diet proved to be effective at controlling polycystic kidney disease

It's official: The ketogenic diet proved to be effective at controlling polycystic kidney disease (PKD) in the first randomized controlled clinical trial of ketogenic metabolic therapy for PKD.

11 Dec 2023

Personalized treatment for leukemia results in longer life and fewer side effects

Personalized treatment for the most common form of adult leukemia helps patients survive for longer and stay in remission, a phase III trial has found.

11 Dec 2023

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Lymphatic fluid from surgical drains, which is usually tossed in the trash, is a treasure in the hands of University of Pittsburgh and Washington University School of Medicine in St. Louis researchers who found that this liquid could inform more precise treatments for patients with head and neck cancer caused by human papillomavirus (HPV).

11 Dec 2023