Genes News and Research

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Researchers find a switch to regulate the diabetes-causing gene

Researchers at the Centre for Genomic Regulation and Imperial College London have found a switch that regulates the activity of a gene that causes diabetes.

27 Oct 2022

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs.

27 Oct 2022

Advanced type of nanoparticle could help fight hard-to-treat cancers

Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers.

27 Oct 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

Researchers assessed whether loss-of-function variants of type I interferon immunity genes are associated with life-threatening COVID-19.

27 Oct 2022

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Researchers reported three human monoclonal antibodies generated from COVID-19-recovered individuals during the initial wave of the pandemic in India.

27 Oct 2022

Cells in the brain's blood vessels necessary for fever reaction

Researchers at Linköping University have identified in mice the cells in the blood vessels of the brain that are necessary for a fever reaction.

26 Oct 2022

Research reveals molecular pathways of aggressive cribriform prostate cancer

Cribriform prostate cancer is an aggressive subtype of the disease characterized by its histology, but little is known about its molecular pathways.

26 Oct 2022

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

A new study aimed to develop a standardized protocol for SARS-CoV-2 RNA detection in semen fractions used for assisted reproductive technology.

26 Oct 2022

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Researchers analyzed the phenotypes of the SARS-CoV-2 variants of concern (VOCs), the molecular responses to infections from these VOCs, and the evolving virus-host interactions using a comparative genomic and proteomic approach.

26 Oct 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

A review of emerging pediatric respiratory viruses

Respiratory viruses continue to be a leading cause of childhood morbidity and mortality.

26 Oct 2022

Newborn screenings more likely to miss cystic fibrosis diagnosis in non-white babies

Researchers call for better newborn screens across the U.S. Cystic fibrosis is missed more often in newborn screenings for non-white than white babies, creating higher risk for irreversible lung damage and other serious outcomes in Black, Hispanic, Asian, American Indian and Alaska Native newborns, a new study finds.

25 Oct 2022

Genomic rearrangements in monkeypox virus could be a sign of adaption to the human host

Researchers explored genomic rearrangements in monkeypox virus genomes and investigated whether such rearrangements represented viral adaption to humans (host).

25 Oct 2022

In utero exposure to flame retardant results in altered brain development in newborn rats

A new study from North Carolina State University shows that exposure in utero to the flame retardant FireMaster 550 (FM 550), or to its individual brominated (BFR) or organophosphate ester (OPFR) components, resulted in altered brain development in newborn rats.

24 Oct 2022

New diagnostic method applies machine learning to advanced genomics data to detect sepsis

Sepsis, the overreaction of the immune system in response to an infection, causes an estimated 20% of deaths globally and as many as 20 to 50% of U.S. hospital deaths each year.

24 Oct 2022

Scientists use systems biology approach to identify molecular players in rheumatoid arthritis

Using a novel systems biology approach, scientists at University of California San Diego School of Medicine have further parsed the cellular players and roles involved in rheumatoid arthritis (RA), a complex disease that affects more than one million Americans in ways that have defied development of uniform treatments.

24 Oct 2022

Dog ownership during infancy might attenuate the risk of persistent wheezing

In a new study, researchers examined the gene-environment (GxE) interactions between pet ownership in infancy and the 17q12-21 (asthma-risk) locus concerning wheezing.

24 Oct 2022

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

In a new study, researchers introduced a compact rapid detection kit that tests for the monkeypox virus using a combination of RPA and CRISPR technology.

24 Oct 2022

Genes News and Research

Researchers find a switch to regulate the diabetes-causing gene

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Advanced type of nanoparticle could help fight hard-to-treat cancers

New discovery may change the textbook model of GPCR-mediated signaling

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Cells in the brain's blood vessels necessary for fever reaction

Research reveals molecular pathways of aggressive cribriform prostate cancer

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

A review of emerging pediatric respiratory viruses

Newborn screenings more likely to miss cystic fibrosis diagnosis in non-white babies

Genomic rearrangements in monkeypox virus could be a sign of adaption to the human host

In utero exposure to flame retardant results in altered brain development in newborn rats

New diagnostic method applies machine learning to advanced genomics data to detect sepsis

Scientists use systems biology approach to identify molecular players in rheumatoid arthritis

Dog ownership during infancy might attenuate the risk of persistent wheezing

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

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