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Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

The nation has been grappling with the opioid epidemic for years - and the city of Philadelphia has been hit hard by the crisis. While data is showing slight declines in overdose deaths, the opioid crisis remains a public health emergency.

4 Oct 2019

Experts discuss sex-specific sensitivity to key blood pressure hormone

Aldosterone is a steroid hormone important to the regulation of salt, fluid and potassium in the body.

4 Oct 2019

Long-term study data shows DBS is effective for patients with treatment-resistant depression

A study published online on Friday, October 4, in the American Journal of Psychiatry found that deep brain stimulation (DBS) of an area in the brain called the subcallosal cingulate (SCC) provides a robust antidepressant effect that is sustained over a long period of time in patients with treatment-resistant depression--the most severely depressed patients who have not responded to other treatments.

4 Oct 2019

New smartphone app can help detect early signs of eye diseases in children

A Baylor University researcher's prototype smartphone app -- designed to help parents detect early signs of various eye diseases in their children such as retinoblastoma, an aggressive pediatric eye cancer -- has passed its first big test.

4 Oct 2019

Penn researchers propose ethical framework that defines brain organoid transplantation

As research involving the transplantation of human "mini-brains"--known as brain organoids--into animals to study disease continues to expand, so do the ethical debates around the practice.

4 Oct 2019

Experts call for public health campaign aimed at promoting 'brain-healthy lifestyle'

Experts are calling for a public health campaign aimed at promoting a 'brain-healthy lifestyle' to reduce the risk of developing neurodegenerative brain diseases, such as Alzheimer's disease and Parkinson's disease.

4 Oct 2019

Connected diabetes care can become part of a new diabetes care model

Digital diabetes management systems ("connected diabetes care") have the potential to become part of a new diabetes care model, augmenting the traditional practice of diabetes care by providing continuous and on-demand assistance that aligns with the 24/7 demands of diabetes as a chronic disease.

3 Oct 2019

Mount Sinai researchers discover how DNA polymerase delta duplicates the genome

Mount Sinai researchers have discovered how the enzyme DNA polymerase delta works to duplicate the genome that cells hand down from one generation to the next. In a study published in Nature Structural & Molecular Biology, the team also reported how certain mutations can modulate the activity of this enzyme, leading to cancers and other diseases.

3 Oct 2019

UMSOM researchers test new CDC recommendations to control nursing home infections

The Centers for Disease Control and Prevention estimates that more than two million people are infected with antibiotic-resistant organisms, resulting in approximately 23,000 deaths annually.

3 Oct 2019

Walmart to give workers financial incentives to use higher-quality doctors

Worried its employees aren't getting good enough care from doctors in their insurance networks, Walmart next year will test pointing workers in northwestern Arkansas, central Florida and the Dallas-Fort Worth area toward physicians it has found provide better service.

3 Oct 2019

UCR biochemist receives grant to develop novel lead compound to treat breast cancer

A biochemist at the University of California, Riverside, has received a grant from the Congressionally Directed Medical Research Programs, or CDMRP, of the U.S. Department of Defense to develop a novel lead compound to treat breast cancer, the second most commonly diagnosed cancer among American women.

3 Oct 2019

The vulnerability to auditory hallucinations in schizophrenia may be established by infancy

Some people suffering from severe mental illness, particularly schizophrenia, hear "voices," known as auditory hallucinations.

3 Oct 2019

Optimism linked to lower risk of cardiac events and all-cause mortality

Having an optimistic mindset is linked to a lower risk of cardiac events and all-cause mortality, according to new research from the Icahn School of Medicine at Mount Sinai.

3 Oct 2019

$Clinical recommendations issued for prevention of secondary fracture among older adults$

Clinical recommendations issued for prevention of secondary fracture among older adults

A multistakeholder coalition assembled by the American Society for Bone and Mineral Research has issued clinical recommendations for the optimal prevention of secondary fracture among people aged 65 years and older with a hip or vertebral fracture - the most serious complication associated with osteoporosis.

2 Oct 2019

Medical professional offers unique perspective as father of a child with rare movement disorder

From a professional standpoint, Nathan Hoot, MD, PhD, understands the value of medical research that leads to new, groundbreaking drugs in the treatment of rare diseases.

1 Oct 2019

Mount Sinai neuroscientist sheds light on how the brain stores memories across a lifetime

Denise Cai, PhD, an Assistant Professor of Neuroscience at the Icahn School of Medicine at Mount Sinai, has always been interested in the dynamic nature of memory. But she began to question precisely how the brain can store and recall so many memories over a lifetime while playing a "memory match" card game with her young son.

1 Oct 2019

Domestic violence may affect mothers' breastfeeding practices in developing countries

Mothers who have suffered from domestic violence are substantially less likely to follow recommended breastfeeding practices in low to middle-income countries, a new study shows.

1 Oct 2019

High-fat diet with high fructose damages mitochondria in the liver, study shows

Researchers at Joslin Diabetes Center have found that high levels of fructose in the diet inhibit the liver's ability to properly metabolize fat.

1 Oct 2019

New study helps better understand how type 2 diabetes progresses as a disease

Researchers at Joslin Diabetes Center, an affiliate of Harvard Medical School, have unlocked the key to clearly identifying diseased beta cells in type 2 diabetes.

1 Oct 2019

Detecting neurocognitive change in children with acute lymphoblastic leukemia

Although cure rates for children with cancer are increasing, cancer treatments can cause permanent deterioration of brain functions leading to impairments in attention, concentration, memory and learning. As a result, these changes can lead to challenges with school, obtaining future employment and overall quality of life into adulthood, even though cancer treatment may have been successful.

1 Oct 2019

Medical School News and Research

Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

Experts discuss sex-specific sensitivity to key blood pressure hormone

Long-term study data shows DBS is effective for patients with treatment-resistant depression

New smartphone app can help detect early signs of eye diseases in children

Penn researchers propose ethical framework that defines brain organoid transplantation

Experts call for public health campaign aimed at promoting 'brain-healthy lifestyle'

Connected diabetes care can become part of a new diabetes care model

Mount Sinai researchers discover how DNA polymerase delta duplicates the genome

UMSOM researchers test new CDC recommendations to control nursing home infections

Walmart to give workers financial incentives to use higher-quality doctors

UCR biochemist receives grant to develop novel lead compound to treat breast cancer

The vulnerability to auditory hallucinations in schizophrenia may be established by infancy

Optimism linked to lower risk of cardiac events and all-cause mortality

Clinical recommendations issued for prevention of secondary fracture among older adults

Medical professional offers unique perspective as father of a child with rare movement disorder

Mount Sinai neuroscientist sheds light on how the brain stores memories across a lifetime

Domestic violence may affect mothers' breastfeeding practices in developing countries

High-fat diet with high fructose damages mitochondria in the liver, study shows

New study helps better understand how type 2 diabetes progresses as a disease

Detecting neurocognitive change in children with acute lymphoblastic leukemia

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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