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Study finds correlation between neutralizing antibody titer and reported vaccine efficacy

An observational study compares immune responses against three vaccines.

29 Sep 2021

Vaccine-induced SARS-CoV2 immune responses decline at similar rates as those after infection, study finds

A new preprint describes the causal role of waning antibody titers in decreased antibody persistence at one year.

29 Sep 2021

New analysis reveals distinct differences between molecular profiles of 3D and 2D cultured cells

Oncotarget published "Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells" which reported that to ascertain phenotypical differences between these two distinct culture conditions, these authors carried out a comparative proteomic analysis of a membrane fraction obtained from 3D- and 2D-cultured NSCLC model cell line NCI-H23.

29 Sep 2021

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Oncotarget published "Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma" which reported that Multiple Myeloma patients suffer disease relapse due to the development of therapeutic resistance. Increasing evidence suggests that immunotherapeutic strategies can provide durable responses.

29 Sep 2021

Combination of two drugs may help pancreatic and liver cancer patients

A drug candidate discovered and developed decades ago in the laboratory of UC Davis distinguished professor Bruce Hammock may help control the body's raging and often deadly inflammatory response to chemotherapy treatments, especially for pancreatic and liver cancer patients.

29 Sep 2021

Human coronavirus replicates in bats without using the spike protein

Researchers in Singapore have conducted a study showing active replication of a human coronavirus in bats that occurred without the viral spike protein binding to host cell receptors.

28 Sep 2021

Southeast Asia - A hotspot of many viruses with potential to cause pandemics

A new study reveals that scientists have found three viruses in bats in Laos that exhibit similar characteristic features as SARS-CoV-2.

28 Sep 2021

Primary sclerosing cholangitis: Therapy with synthetic bile acid acts directly on the immune system

Primary Sclerosing Cholangitis (PSC) is a rare, chronic inflammatory disease of the bile ducts and is difficult to treat. Studies conducted by the Division of Gastroenterology and Hepatology at MedUni Wien under the guidance of Michael Trauner (Department of Internal Medicine III) were able to show positive effects from the administration of synthetically produced bile acids and bile acid receptor agonists.

28 Sep 2021

COVID-19 vaccination reduces risk and duration of SARS-CoV-2 infection

In a study conducted at the European Institute of Oncology, scientists have found that the risk and duration of SARS-CoV-2 infection reduced significantly after COVID-19 vaccination.

28 Sep 2021

Caspase-11 identified as regulator of inflammatory pathology in SARS-CoV-2 infections

New findings identify CASP4/11 as detrimental to inflammation and coagulopathy associated with SARS-CoV-2 infection.

28 Sep 2021

Researchers discover working mechanism of potential drug targets for COVID-19

A team of international researchers, including McGill Professor Stéphane Laporte, have discovered the working mechanism of potential drug targets for various diseases such as cancer, rheumatoid arthritis, and even COVID-19.

28 Sep 2021

Scientists identify potential antibody candidate with broad-spectrum neutralizing efficacy against SARS-CoV-2 variants

A team of scientists from China and the USA has recently described the antiviral efficacy of a monoclonal antibody candidate targeting the spike receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Importantly, they have observed that emerging spike mutations could not affect the potency of this antibody. The study is currently available on the bioRxiv* preprint server.

27 Sep 2021

Researchers discover protein previously unknown to be involved in SARS-CoV-2 infection

Researchers in the UK and Germany have provided evidence for a novel mechanism by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – binds to human host cells.

27 Sep 2021

Drug treatment decreases risk for severe COVID-19 outcomes in patients with Type 2 diabetes

A type of drug already used to treat obesity and Type 2 diabetes, when taken six months prior to the diagnosis of COVID-19, was associated with a decreased risk of hospitalization, respiratory complications and death in COVID-19 patients with Type 2 diabetes, according to researchers at Penn State College of Medicine.

27 Sep 2021

Receptor News and Research

Study finds correlation between neutralizing antibody titer and reported vaccine efficacy

Vaccine-induced SARS-CoV2 immune responses decline at similar rates as those after infection, study finds

New analysis reveals distinct differences between molecular profiles of 3D and 2D cultured cells

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Combination of two drugs may help pancreatic and liver cancer patients

Human coronavirus replicates in bats without using the spike protein

Southeast Asia - A hotspot of many viruses with potential to cause pandemics

Primary sclerosing cholangitis: Therapy with synthetic bile acid acts directly on the immune system

COVID-19 vaccination reduces risk and duration of SARS-CoV-2 infection

Caspase-11 identified as regulator of inflammatory pathology in SARS-CoV-2 infections

Researchers discover working mechanism of potential drug targets for COVID-19

Scientists identify potential antibody candidate with broad-spectrum neutralizing efficacy against SARS-CoV-2 variants

Researchers discover protein previously unknown to be involved in SARS-CoV-2 infection

Drug treatment decreases risk for severe COVID-19 outcomes in patients with Type 2 diabetes

Breast radiation after lumpectomy decreases incidence of ipsilateral breast recurrence for 'low risk' DCIS

Third COVID-19 mRNA vaccine booster dose indicated for myelofibrosis patients

Monoclonal antibodies may reduce hospital stay, but not mortality in COVID-19

Chronic COVID-19 and divergent variants of SARS-CoV-2

A new SARS-CoV-2 variant (B.1.1.523) capable of escaping immune protections

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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