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Cedars-Sinai earns grant to conduct clinical trial of gene therapy product for patients with Lou Gehrig's disease

The Cedars-Sinai Regenerative Medicine Institute has received a $2.5 million grant from the Department of Defense to conduct animal studies that, if successful, could provide the basis for a clinical trial of a gene therapy product for patients with Lou Gehrig's disease, also called amyotrophic lateral sclerosis, or ALS.

2 Apr 2014

High levels of GDNF protein could help body resist weight gain despite high-fat diet

More than one-third of people in the US are obese. Obesity and its related health problems-including high blood pressure, high cholesterol, diabetes, insulin resistance, and belly fat-affect so many, yet effective treatments are very few.

2 Apr 2014

NeuroSigma gets approval to market Monarch eTNS System in Australia

NeuroSigma, Inc., a California-based life-sciences company focused on commercialization of its non-invasive Monarch eTNS System for the treatment of neurological and neuropsychiatric disorders, today announced that it has received approval from the Therapeutic Goods Administration to market its Monarch eTNS System in Australia.

1 Apr 2014

DTI assessment indicates that mild hypothermia therapy may be beneficial for patients with diffuse axonal injury

Mild hypothermia has been shown to exert apparent neuroprotective effects in animal models of diffuse axonal injury. However, the clinical efficacy of mild hypothermia is controversial.

1 Apr 2014

Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

A new discovery suggests it could one day be possible to chemically reprogram and repair damaged nerves after spinal cord injury or brain trauma.

1 Apr 2014

New research implicates that RNA processing is central to ALS disease process

In work supported by The ALS Association, researchers have discovered a new ALS-causing gene and have linked its function to that of another prominent disease gene. The study was published in the journal Nature Neuroscience.

1 Apr 2014

Sodium pump plays vital role in nerve impulses, heartbeats and muscular contraction

A study in The Journal of General Physiology provides new evidence that the ubiquitous sodium pump is more complex-and more versatile-than we thought.

1 Apr 2014

Experimental anticancer compound appears to reverse behaviors associated with schizophrenia

Johns Hopkins researchers say that an experimental anticancer compound appears to have reversed behaviors associated with schizophrenia and restored some lost brain cell function in adolescent mice with a rodent version of the devastating mental illness.

1 Apr 2014

Potassium boost improves walking, prolongs survival in mouse model of Huntington's disease

Tweaking a specific cell type's ability to absorb potassium in the brain improved walking and prolonged survival in a mouse model of Huntington's disease, reports a UCLA study published March 30 in the online edition of Nature Neuroscience. The discovery could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans.

31 Mar 2014

Einstein faculty members present recent research at AACR Annual Meeting

From uncovering the role nerve cells play in metastasis to identifying new cancer-causing genes, researchers at Albert Einstein College of Medicine of Yeshiva University made notable advances in the understanding and potential treatment of cancer during the past year.

29 Mar 2014

Veterans who suffer from "Gulf War illness" have impaired function of mitochondria

Researchers at the UC San Diego School of Medicine have demonstrated for the first time that veterans of the 1990-91 Persian Gulf War who suffer from "Gulf War illness" have impaired function of mitochondria - the energy powerhouses of cells.

28 Mar 2014

Early life chronic stress may cause anxiety in adulthood, says study

In recent years, behavioral neuroscientists have debated the meaning and significance of a plethora of independently conducted experiments seeking to establish the impact of chronic, early-life stress upon behavior - both at the time that stress is experienced, and upon the same individuals later in life, during adulthood.

28 Mar 2014

Scientists discover role of protons in neurotransmission

While probing how organisms sense gravity and acceleration, scientists at the Marine Biological Laboratory (MBL) and the University of Utah uncovered evidence that acid (proton concentration) plays a key role in communication between neurons.

27 Mar 2014

Study points to potential culprit that kills motor neurons in ALS

Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is marked by a cascade of cellular and inflammatory events that weakens and kills vital motor neurons in the brain and spinal cord. The process is complex, involving cells that ordinarily protect the neurons from harm. Now, a new study by scientists in The Research Institute at Nationwide Children's Hospital points to a potential culprit in this good-cell-gone-bad scenario, a key step toward the ultimate goal of developing a treatment.

27 Mar 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died.

26 Mar 2014

Stem cell research opens doors to potential new treatments for bipolar disorder

What makes a person bipolar, prone to manic highs and deep, depressed lows? Why does bipolar disorder run so strongly in families, even though no single gene is to blame? And why is it so hard to find new treatments for a condition that affects 200 million people worldwide?

26 Mar 2014

Axonics Modulation Technologies completes $32.6 million Series A preferred stock financing

Axonics Modulation Technologies, Inc., a developer of novel implantable neuromodulation technology, announced today that it has completed a $32.6 million Series A preferred stock financing.

25 Mar 2014

New subcellular mechanism identified for fast transmission in basket cells of the brain

In his third major research paper since December 2013, IST Austria Professor Peter Jonas together with his collaborator, postdoc Hua Hu, identifies a new subcellular mechanism for reliable, fast transmission in the so-called basket cells of the brain.

25 Mar 2014

Viewpoints on challenge to contraceptive coverage mandate

This week, the owners of two secular, for-profit corporations will ask the Supreme Court to take a radical turn and allow them to impose their religious views on their employees - by refusing to permit them contraceptive coverage as required under the Affordable Care Act. The Supreme Court has consistently resisted claims for religious exemptions from laws that are neutral and apply broadly when the exemptions would significantly harm other people, as this one would. To approve it would flout the First Amendment, which forbids government from favoring one religion over another - or over nonbelievers (3/22).

25 Mar 2014

New research reveals new complexity to nerve cells in brain that could affect future therapies

Research from the Oklahoma Medical Research Foundation reveals a new complexity to nerve cells in the brain that could affect future therapies aimed at altering mood and memory in humans.

25 Mar 2014

Nerve News and Research

Cedars-Sinai earns grant to conduct clinical trial of gene therapy product for patients with Lou Gehrig's disease

High levels of GDNF protein could help body resist weight gain despite high-fat diet

NeuroSigma gets approval to market Monarch eTNS System in Australia

DTI assessment indicates that mild hypothermia therapy may be beneficial for patients with diffuse axonal injury

Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

New research implicates that RNA processing is central to ALS disease process

Sodium pump plays vital role in nerve impulses, heartbeats and muscular contraction

Experimental anticancer compound appears to reverse behaviors associated with schizophrenia

Potassium boost improves walking, prolongs survival in mouse model of Huntington's disease

Einstein faculty members present recent research at AACR Annual Meeting

Veterans who suffer from "Gulf War illness" have impaired function of mitochondria

Early life chronic stress may cause anxiety in adulthood, says study

Scientists discover role of protons in neurotransmission

Study points to potential culprit that kills motor neurons in ALS

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

Stem cell research opens doors to potential new treatments for bipolar disorder

Axonics Modulation Technologies completes $32.6 million Series A preferred stock financing

New subcellular mechanism identified for fast transmission in basket cells of the brain

Viewpoints on challenge to contraceptive coverage mandate

New research reveals new complexity to nerve cells in brain that could affect future therapies

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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