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Research may provide a new way to treat organ scarring

Scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Medicine 3 - Rheumatology and Immunology, headed by Prof. Dr. Georg Schett, have now decrypted a molecular network that controls these processes and could in future provide a new way to treat organ scarring.

1 Feb 2019

Study: IL10 receptor critical to prevent uncontrolled infection and gut damage

A new study has identified the master regulator that maintains a healthy gut and limits damage by parasitic whipworms.

1 Feb 2019

Newly discovered molecules show potential to treat obesity and fatty liver disease

Amiram Goldblum and his team at the Hebrew University of Jerusalem's Institute for Drug Research have discovered 27 new molecules. These molecules all activate a special protein called PPAR-delta and have the potential to treat fatty liver disease, obesity, diabetic nephrotoxicity, and to heal wounds.

31 Jan 2019

Scientists explore new treatment targets for retinal damage

Scientists at the Medical College of Georgia at Augusta University are looking at new treatment targets for the retinal damage that often accompanies diseases like diabetes, glaucoma and hypertension.

31 Jan 2019

Study opens new avenue for treating ulcerative colitis or Crohn's disease

An international study led by the Complutense University of Madrid (UCM) and the National Centre for Cardiovascular Research (CNIC) has found that Lactobacillus bacteria present in the intestinal microbiota interact with immune system cells to strengthen the intestinal barrier.

31 Jan 2019

Novel 3D imaging method reveals how pancreatic cancers originate

A new technique to study tissue samples in 3D has revealed that pancreatic cancers can start and grow in two distinct ways, solving a decades-old mystery of how tumors form.

From The Francis Crick Institute 30 Jan 2019

PFAS chemicals pass through the placenta to fetal tissues throughout pregnancy

In a study published in Environment International researchers at Karolinska Institutet in Sweden show how PFAS industrial chemicals, which are used in many consumer products, pass through the placenta throughout pregnancy to accumulate in fetal tissue.

30 Jan 2019

Researchers identify new therapeutic targets for kidney fibrosis

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population--and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis.

29 Jan 2019

Community hospitals link arms with prestigious facilities to raise their profiles

After seven years of a vigorous fight, Jim Hart worried he was running out of options. Diagnosed with prostate cancer at age 60, Hart had undergone virtually every treatment — surgery, radiation and hormones — to eradicate it. But a blood test showed that his level of prostate-specific antigen, which should have been undetectable, kept rising ominously. And doctors couldn’t determine where the residual cancer was lurking.

29 Jan 2019

Researchers compare treatment options for fecal incontinence

It is a common health problem that causes uncommon personal discomfort. Fecal incontinence, or accidental stool leakage, affects some 8 to 10 percent of the 325 million people in the United States. In up to half of patients, there is both fecal and urinary incontinence.

29 Jan 2019

EU research project is studying the effect of endocrine disruptors on metabolism

January 2019 saw the launch of the EU research project EDCMET, in which scientists from the German Federal Institute for Risk Assessment (BfR) are also involved.

28 Jan 2019

New class of antisense oligonucleotide therapeutics tested in humans

A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Jan 2019

Discovery reveals how to 'slim down' fat-carrying particles to reduce spread of 'bad' cholesterol

The enzyme that 'loads up' fat-carrying particles in the liver before they are transported around the body has been identified for the first time by scientists at the University of Warwick.

28 Jan 2019

Scientists pinpoint mechanism that leads to steroid diabetes

Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich, partners in the German Center for Diabetes Research, have now pinpointed a mechanism that leads to so-called steroid diabetes

25 Jan 2019

Standard method for ranking liver transplant waitlists may not prioritize the sickest candidates

A new study has uncovered that the standard method for ranking patients on the waitlist for lifesaving liver transplantation may not prioritize some of the sickest candidates for the top of the list.

25 Jan 2019

Clinical Design launches world’s only hygienic digital urine test at Arab Health 2019

The world’s only hygienic, easy-to-use and accurate digital point-of-care urine test is being launched at Arab Health 2019 by UK company, Clinical Design.

24 Jan 2019

CMV vaccine provides a new way to fight malaria

Early research on a new approach to protecting against malaria is offering promising, potentially long-lasting results against the persistent parasite that sickens hundreds of millions people each year.

24 Jan 2019

Researchers identify major compounds that impart taste to pufferfish without harmful toxin

Some people consider pufferfish, also known as fugu, a delicacy because of its unique and exquisite flavor, which is perhaps seasoned by knowledge that consumption of the fish could be deadly.

24 Jan 2019

Study reveals cost-effectiveness of needle and syringe programs in preventing HCV transmission

Providing clean injecting equipment through needle and syringe programmes is a highly cost-effective way of preventing hepatitis C transmission among people who inject drugs and could save millions of pounds in infection treatment costs in the UK, according to research led by the University of Bristol and London School of Hygiene & Tropical Medicine.

24 Jan 2019

Low-sugar diet leads to significant improvement in nonalcoholic fatty liver disease in boys

Researchers at University of California San Diego School of Medicine and Emory University School of Medicine found that a diet low in free sugars resulted in significant improvement in nonalcoholic fatty liver disease in adolescent boys.

23 Jan 2019

Liver News and Research

Research may provide a new way to treat organ scarring

Study: IL10 receptor critical to prevent uncontrolled infection and gut damage

Newly discovered molecules show potential to treat obesity and fatty liver disease

Scientists explore new treatment targets for retinal damage

Study opens new avenue for treating ulcerative colitis or Crohn's disease

Novel 3D imaging method reveals how pancreatic cancers originate

PFAS chemicals pass through the placenta to fetal tissues throughout pregnancy

Researchers identify new therapeutic targets for kidney fibrosis

Community hospitals link arms with prestigious facilities to raise their profiles

Researchers compare treatment options for fecal incontinence

EU research project is studying the effect of endocrine disruptors on metabolism

New class of antisense oligonucleotide therapeutics tested in humans

Discovery reveals how to 'slim down' fat-carrying particles to reduce spread of 'bad' cholesterol

Scientists pinpoint mechanism that leads to steroid diabetes

Standard method for ranking liver transplant waitlists may not prioritize the sickest candidates

Clinical Design launches world’s only hygienic digital urine test at Arab Health 2019

CMV vaccine provides a new way to fight malaria

Researchers identify major compounds that impart taste to pufferfish without harmful toxin

Study reveals cost-effectiveness of needle and syringe programs in preventing HCV transmission

Low-sugar diet leads to significant improvement in nonalcoholic fatty liver disease in boys

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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