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How SARS-CoV-2 evolved from a bat-to a human-adapted virus

New research published on the preprint server bioRxiv* performed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic simulations to understand the evolutionary transition from a bat-adapted SARS-CoV-2 to a human-adapted virus.

19 May 2021

Study identifies mechanism behind SARS-CoV-2 fusion of host cells

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the fusion of the spike protein to nearby healthy cells. New research by German researchers sheds light on how this happens.

19 May 2021

Researchers find new clue to restore congenital hearing loss

Researchers at Oregon State University have found a key new piece of the puzzle in the quest to use gene therapy to enable people born deaf to hear.

19 May 2021

Animal and insect invasions could shed light on COVID-19 transmission

Invasions by alien insect and animal species have much in common with outbreaks of infectious diseases and could tell us a great deal about how pandemics spread, according to a research paper published today.

19 May 2021

Latest round of REACT-1 finds SARS-CoV-2 prevalence has halved since previous round

Researchers in the UK say the latest round of the REal-time Assessment of Community Transmission-1 (REACT-1) study has found that the prevalence of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – has fallen by 50%, compared with the previous round conducted in March of this year (2021).

19 May 2021

Lengthy treatment with low-dose 6-mercaptopurine inhibits resistant triple-negative breast cancer cells

The cover for issue 7 of Oncotarget features Figure 5, "SUM149-MA cells surviving a 6-MP treatment are sensitive to chemotherapeutic drugs," published in "Inhibition of resistant triple-negative breast cancer cells with low-dose 6-mercaptopurine and 5-azacitidine" by Singh, et al. which reported that the authors have reported that a lengthy treatment with low-dose 6-mercaptopurine, a clinically useful anti-inflammatory drug, inhibits such resistant cells.

19 May 2021

Study investigates mental health consequences of COVID-19 geriatric care in nursing homes

No matter one's age, race, gender, socioeconomic status or political party, COVID-19 has impacted everyone at some level. That impact has been especially palpable for the approximately 1.3 million elderly Americans who reside in the country's 15,600 nursing homes.

19 May 2021

Survey shows racial and ethnic differences in use of personal care products

A large survey of women in California shows significant racial and ethnic differences in the types of personal care products women use on a daily basis.

19 May 2021

Study validates predictive model for identifying pediatric patients at risk for developing blood clots

Monroe Carell Jr. Children's Hospital at Vanderbilt has launched a study to determine the impact of a predictive model for identifying pediatric patients at risk for developing blood clots or venous thromboembolisms (VTEs).

19 May 2021

Randomized clinical trials compare effects of coronary revascularization versus medical therapy alone

A rigorous meta-analysis of randomized clinical trials (RCTs) that compared the effects of medical therapies alone with medical therapies plus revascularization in patients with stable ischemic heart disease (SIHD) was presented at EuroPCR on May 18, 2021.

19 May 2021

Researchers found disparities for COVID-19 testing and positivity rates in West Virginia

In studying COVID-19 testing and positivity rates in West Virginia between March and September 2020, West Virginia University researchers found disparities among Black residents and residents experiencing food insecurity.

19 May 2021

New study will help investigate innate immune responses to viral infections

Researchers from Boston University School of Medicine (BUSM) report the formation of human cells containing a green fluorescent protein or GFP (one of the most important proteins in biology and fluorescence imaging) genetically fused with two interferon stimulated genes (ISGs), namely Viperin and ISG15.

19 May 2021

New approach could allow cardiologists to predict future heart attacks in high-risk patients

Analysing the forces at work behind the obstructions that cause heart attacks is crucial for identifying patients at risk of these events, says a study published today in eLife.

19 May 2021

Scientists provide a new approach to model infectious diseases

In the midst of a devastating global pandemic of wildlife origin and with future spillovers imminent as humans continue to come into closer contact with wildlife, infectious-disease models that consider the full ecological and anthropological contexts of disease transmission are critical to the health of all life.

19 May 2021

Researchers propose new way to treat chronic lung condition

Traditionally, an infection is thought to happen when microbes - bacteria, fungi, or viruses - enter and multiply in the body, and its severity is associated with how prevalent the microbes are in the body.

19 May 2021

Study reveals four coagulation measures associated with migraine susceptibility

Nearly 15 percent of the U.S. population experiences migraine. One subtype of migraine that is not well understood is migraine with aura (MA).

19 May 2021

Social interventions also prolong life in medical patients

New research from BYU published in PLOS Medicine found that providing medical patients with social support leads to an increased chance of survival and elongation of life.

19 May 2021

Genetic mutation associated with autism can impair oxytocin-mediated social behavior

Autism spectrum disorder is a neurodevelopmental condition involving impaired social abilities, and this makes it a fascinating subject for neuroscientists like Prof. Teiichi Furuichi of the Tokyo University of Science who study the neuroscience of social behavior.

19 May 2021

New mathematical model predicts how bacterial mutations influence the success of antibiotic treatments

Scientists have developed a mathematical model that predicts how the number and effects of bacterial mutations leading to drug resistance will influence the success of antibiotic treatments.

19 May 2021

DNAM-1 receptor could be used as new molecular target for treating autoimmune diseases

Autoimmune diseases occur when an individual's immune system fights their own body as if it was a foreign invader. However, in healthy people, these responses are prevented by a process known as immune tolerance

19 May 2021

Research News and Research

How SARS-CoV-2 evolved from a bat-to a human-adapted virus

Study identifies mechanism behind SARS-CoV-2 fusion of host cells

Researchers find new clue to restore congenital hearing loss

Animal and insect invasions could shed light on COVID-19 transmission

Latest round of REACT-1 finds SARS-CoV-2 prevalence has halved since previous round

Lengthy treatment with low-dose 6-mercaptopurine inhibits resistant triple-negative breast cancer cells

Study investigates mental health consequences of COVID-19 geriatric care in nursing homes

Survey shows racial and ethnic differences in use of personal care products

Study validates predictive model for identifying pediatric patients at risk for developing blood clots

Randomized clinical trials compare effects of coronary revascularization versus medical therapy alone

Researchers found disparities for COVID-19 testing and positivity rates in West Virginia

New study will help investigate innate immune responses to viral infections

New approach could allow cardiologists to predict future heart attacks in high-risk patients

Scientists provide a new approach to model infectious diseases

Researchers propose new way to treat chronic lung condition

Study reveals four coagulation measures associated with migraine susceptibility

Social interventions also prolong life in medical patients

Genetic mutation associated with autism can impair oxytocin-mediated social behavior

New mathematical model predicts how bacterial mutations influence the success of antibiotic treatments

DNAM-1 receptor could be used as new molecular target for treating autoimmune diseases

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