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New drug shows promise for treating chronic neuropathic pain

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute.

2 Aug 2023

Insilico Medicine uses AI to discover novel SIK2 inhibitors

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

2 Aug 2023

Novel molecules inspired by the immune system inactivate several viruses

Antiviral therapies are notoriously difficult to develop, as viruses can quickly mutate to become resistant to drugs. But what if a new generation of antivirals ignores the fast-mutating proteins on the surface of viruses and instead disrupts their protective layers?

2 Aug 2023

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

With a survival rate in the single digits, pancreatic ductal adenocarcinoma (PDAC) is highly lethal. In fact, by the time PDAC is clinically diagnosed, it is already considered incurable via surgery or other means in up to 90% of patients.

2 Aug 2023

Peptoid antiviral therapy inactivates three viruses in lab tests

Just as bacteria can develop antibiotic resistance, viruses can also evade drug treatments. Developing therapies against these microbes is difficult because viruses often mutate or hide themselves within cells.

2 Aug 2023

Study assesses the value of predictive biomarkers for early-stage COVID-19 infection

Researchers illustrated that certain biomarkers may be better predictors of COVID-19 than others.

2 Aug 2023

The influence of electronic cigarette aerosol and cigarette smoke on cardiovascular, gastrointestinal, and renal functions in mice

The toxic effects of aerosol exposure from electronic cigarettes (ECs) and cigarette smoke (CS) on mice.

2 Aug 2023

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

Researchers performed a genome-wide association study to explore whether biomarker levels are causally related to COVID-19 hospitalization.

2 Aug 2023

How does the Mediterranean Diet impact the gut microbiome and cognitive performance African American obese adults?

The effects of the Mediterranean Diet (Med Diet) and intentional weight loss (IWL) on the gut microbiome.

2 Aug 2023

Can vitamin D have positive effects on reducing cortical pathology, oxidative stress, and neurofilament light chain serum levels?

Researchers use an established murine model of cortical inflammatory demyelination to investigate the effects of vitamin D.

2 Aug 2023

The impact of medicinal plants on the gut microbiome in cancer

Researchers evaluate the associations between medicinal plants, the gut microbiome, and cancer.

2 Aug 2023

Analytical and clinical evaluation of antigen-based rapid diagnostic tests against the most encountered SARS-CoV-2 variants

A recent study has assessed the sensitivity of Ag-RDTs against the most prevalent BA.5 Omicron sub-lineage.

2 Aug 2023

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

In a recent study, researchers working at Ohio State University in the United States of America (USA) developed an intranasal subunit vaccine.

2 Aug 2023

New treatment offers hope for children suffering from rare skin condition

It’s a beautiful moniker, but for Australia’s ‘butterfly children’ it belies a devastating reality filled with enormous pain and suffering caused by a rare skin condition – Epidermolysis Bullosa (EB).

2 Aug 2023

Rapid test could determine the existence of a key driver of severe asthma

Based on decades of work to uncover the underlying mechanisms of asthma and other respiratory conditions, researchers at McMaster University and St. Joseph's Healthcare Hamilton have produced a simple, rapid test that can identify the presence of a key driver of severe asthma.

2 Aug 2023

Protein C News and Research

New drug shows promise for treating chronic neuropathic pain

Insilico Medicine uses AI to discover novel SIK2 inhibitors

Novel molecules inspired by the immune system inactivate several viruses

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

Peptoid antiviral therapy inactivates three viruses in lab tests

Study assesses the value of predictive biomarkers for early-stage COVID-19 infection

The influence of electronic cigarette aerosol and cigarette smoke on cardiovascular, gastrointestinal, and renal functions in mice

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

How does the Mediterranean Diet impact the gut microbiome and cognitive performance African American obese adults?

Can vitamin D have positive effects on reducing cortical pathology, oxidative stress, and neurofilament light chain serum levels?

The impact of medicinal plants on the gut microbiome in cancer

Analytical and clinical evaluation of antigen-based rapid diagnostic tests against the most encountered SARS-CoV-2 variants

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

New treatment offers hope for children suffering from rare skin condition

Rapid test could determine the existence of a key driver of severe asthma

Boston College researcher receives grant to study role of gut microbes in Type 1 diabetes

Antiviral protein protects against COVID-19 in live mouse models

Penn Medicine and CHOP receive $26 million NIH grant to develop treatments for three rare genetic diseases

ICI therapy linked to unique immune response in arthritis

Scientists develop breakthrough technology for detecting protein modifications

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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