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Researchers use Thai water bug to find clues for heart muscle diseases

What can a Thai water bug teach us about our muscles, especially the heart? A lot, says Professor of Biological Science Kenneth Taylor. New research by Taylor published today in Science Advances gives scientists better insight into how the heart muscle works and how sometimes it fails.

30 Sep 2016

Researchers discover how cells know when to stop producing mRNA

A new scientific study conducted by a team of leading geneticists has characterized how cells know when to stop translating DNA into proteins, a critical step in maintaining healthy protein levels and cell function.

30 Sep 2016

Tools of Undiagnosed Diseases Network help unravel mystery of rare genetic disease

The first patient was a mystery. Arriving at Duke six years ago at the age of three, the youngster had mild developmental delays and physical characteristics that included a large body and large head circumference.

29 Sep 2016

Recycling existing drugs may help fight several types of cancer

Researchers at the University of Bergen have discovered that a drug against kidney cancer possibly can fight several types of cancer.

29 Sep 2016

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Imran Noorani MD, MRCS, of Cambridge, England, received the Brainlab Community Neurosurgery Abstract Award at the Congress of Neurological Surgeons Annual Meeting in San Diego.

28 Sep 2016

Tau PET imaging in Alzheimer's disease increases opportunities for developing effective drugs

Tau PET is a new and promising imaging method for Alzheimer's disease. A case study from Lund University in Sweden now confirms that tau PET images correspond to a higher degree to actual changes in the brain. According to the researchers behind the study, this increases opportunities for developing effective drugs.

28 Sep 2016

Researchers aim to discover new treatments for triple-negative breast cancer

The precision medicine approach involving DNA sequencing to pinpoint specific alterations that can be targeted with anti-cancer therapies is becoming an alternate treatment avenue for those with poor-responding cancers.

28 Sep 2016

Researchers link RHOX gene mutations to infertility in men

The underlying cause of male infertility is unknown for 30 percent of cases. In a pair of new studies, researchers at University of California San Diego School of Medicine determined that the reproductive homeobox (RHOX) family of transcription factors — regulatory proteins that activate some genes and inactivate others — drive the development of stem cells in the testes in mice.

27 Sep 2016

Adolescent girls with family breast cancer history do not experience negative psychological effects

More and more girls are expected to have to confront breast cancer fears as modern genomics technology makes it easier to detect strong risk factors such as inherited BRCA1/2 mutations.

27 Sep 2016

Increasing specific brain fats could be potential strategy for preventing epileptic seizures

Increasing the concentration of specific fats in the brain could suppress epileptic seizures. This is evident from ground-breaking research carried out by the research groups of Professor Patrik Verstreken and Professor Wim Versées.

26 Sep 2016

Research shows degenerative diseases affecting the retina may be treatable with gene therapy

Researchers have demonstrated the ability to deliver a fully functional copy of the CLN3 gene to stem cells of patients with juvenile NCL, an inherited neurodegenerative disease in which a mutation in the CLN3 gene causes early-onset severe central vision loss.

26 Sep 2016

Specific high-fat diets linked to increased tumor formation in mouse model of intestinal cancer

A high-fat-diet-induced immune reaction causes inflammation leading to intestinal cancer in a mouse model - even among animals that are not obese -- according to a new study from the Perelman School of Medicine at the University of Pennsylvania, Case Western Reserve University, the Pacific Northwest Research Institute, and others.

26 Sep 2016

New NCCN Guidelines outline diagnosis, treatment strategies for myeloproliferative neoplasms

Myeloproliferative Neoplasms (MPN) are a group of blood cancers characterized by significant symptoms and a high risk of transformation into acute leukemia.

26 Sep 2016

Researchers identify, validate three distinct molecular subtypes of prostate cancer

In the largest study of its kind to date, researchers have identified and validated three distinct molecular subtypes of prostate cancer that correlate with distant metastasis-free survival and can assist in future research to determine how patients will respond to treatment, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

Approval of PD-1 inhibitor scratches surface of potential immunotherapies in recurrent HNSCC

The recent approval of pembrolizumab (Keytruda) in recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) following progression on a platinum-based chemotherapy was a significant advancement for the disease.

26 Sep 2016

Salk scientist Clodagh O'Shea named recipient of grant from Faculty Scholars Program

Clodagh O'Shea, an associate professor in the Salk Institute's Molecular and Cell Biology Laboratory, is among the first recipients of a grant from the Faculty Scholars Program, a new partnership of Howard Hughes Medical Institute, the Bill & Melinda Gates Foundation and the Simons Foundation for early career researchers whose work shows the potential for groundbreaking contributions in their fields.

24 Sep 2016

Veracyte announces new data suggesting ability of Afirma GEC in thyroid cancer diagnosis

Veracyte, Inc.today announced new data suggesting the potential to enhance the performance of the Afirma Gene Expression Classifier in thyroid cancer diagnosis by combining the test's proven RNA expression-based capabilities with gene variant and fusion information – all on a single, robust RNA sequencing platform.

24 Sep 2016

New global map shines light on genetic roots of diseases

A global genetic interaction map is revolutionizing how genes are being studied. A new study, involving University of Minnesota researchers, is no longer looking at genes as loners, but instead as a social network of the body, interacting in groups. The new approach may ultimately change our understanding of the genetic roots of diseases.

23 Sep 2016

Gene editing of hematopoietic stem cells can cure many hereditary and congenital diseases

Recent advances in gene editing technology, which allows for targeted repair of disease-causing mutations, can be applied to hematopoietic stem cells with the potential to cure a variety of hereditary and congenital diseases.

23 Sep 2016

Scientists find way to reverse malfunctioning protein clumps involved in ALS

In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming their cellular machinery.

22 Sep 2016

Mutation News and Research

Researchers use Thai water bug to find clues for heart muscle diseases

Researchers discover how cells know when to stop producing mRNA

Tools of Undiagnosed Diseases Network help unravel mystery of rare genetic disease

Recycling existing drugs may help fight several types of cancer

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Tau PET imaging in Alzheimer's disease increases opportunities for developing effective drugs

Researchers aim to discover new treatments for triple-negative breast cancer

Researchers link RHOX gene mutations to infertility in men

Adolescent girls with family breast cancer history do not experience negative psychological effects

Increasing specific brain fats could be potential strategy for preventing epileptic seizures

Research shows degenerative diseases affecting the retina may be treatable with gene therapy

Specific high-fat diets linked to increased tumor formation in mouse model of intestinal cancer

New NCCN Guidelines outline diagnosis, treatment strategies for myeloproliferative neoplasms

Researchers identify, validate three distinct molecular subtypes of prostate cancer

Approval of PD-1 inhibitor scratches surface of potential immunotherapies in recurrent HNSCC

Salk scientist Clodagh O'Shea named recipient of grant from Faculty Scholars Program

Veracyte announces new data suggesting ability of Afirma GEC in thyroid cancer diagnosis

New global map shines light on genetic roots of diseases

Gene editing of hematopoietic stem cells can cure many hereditary and congenital diseases

Scientists find way to reverse malfunctioning protein clumps involved in ALS

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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