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MIT researchers develop new machine to rapidly produce customized peptides

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections.

27 Feb 2017

Diagnosing Infections Through Molecules in Patient Breath

Over the past couple of decades, the analytical technology and the clinical microbiology insight needed to create a breath test for infections has seen a considerable number of advances and there are now numerous research teams focused on evaluating patient breath as a diagnostic fluid for infectious diseases. Significant challenges still need to be overcome.

From Pittcon 27 Feb 2017

New study finds huge problem of multi-drug resistant infections among children

In a new, first-of-its-kind study, researchers from Case Western Reserve University School of Medicine have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family resistant to multiple kinds of antibiotics among children in the US. These antibiotic resistant infections are in turn linked to longer hospital stays and potentially greater risk of death.

24 Feb 2017

Researchers chart pathway of multidrug resistant bacteria living in hospital sink drainpipes

Many recent reports have found multidrug resistant bacteria living in hospital sink drainpipes, putting them in close proximity to vulnerable patients.

24 Feb 2017

Structure of unique amyloid fibrils could lead to discovery of new antibiotics

The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients at hospitals contract a staph infection. It is the bacteria responsible for MRSA, for which there is no vaccine.

24 Feb 2017

UC San Diego researchers suggest transplanting good bacteria to treat patients with atopic dermatitis

Healthy human skin is alive with bacteria. In fact, there are more microorganisms living in and on the human body than there are human cells. Most can live on the human skin without harming the host, but in some people bacteria can negatively alter their health, maybe even become life-threatening.

23 Feb 2017

New research pinpoints how immigrant microbes get to the lungs

They traveled a huge distance, evaded a protective barrier, and found themselves in a strange and unwelcoming land.

23 Feb 2017

Duke Health scientists identify proteins in mucous that confirm viral infection

It may seem obvious, but the key to confirming whether someone is suffering from a cold or flu virus might lie at the misery's source -- the inflamed passages of the nose and throat.

22 Feb 2017

Study describes how bacteria can remodel gene expression to infect intestines of host

Hebrew University researchers have described how infectious bacteria can sense they're attached to our intestinal cells, and then remodel their expression of specific genes, including those involved in virulence and metabolism, to exploit our cells and colonize our gut.

22 Feb 2017

First breath of newborn shapes lifelong immunological milieu of lungs

The lung is an important interface between the body and the outside environment: with each breath, a surface of roughly 100 square meters exchanges oxygen for carbon dioxide. More than 10,000 liters of air pass adult lungs every day and with this come numerous viruses, bacteria and pollutants, which need to be prevented from entering the body.

22 Feb 2017

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines.

22 Feb 2017

Scientists identify novel mutations in bacteria that promote evolution of antibiotic resistance

Scientists from the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, have identified novel mutations in bacteria that promote the evolution of high-level antibiotic resistance.

21 Feb 2017

Scientists engineer smallest CRISPR-Cas9 system to date

Scientists at the Center for Genome Engineering, within the Institute for Basic Science0, in collaboration with KIM Eunji and KIM Jeong Hun have engineered the smallest CRISPR-Cas9 to date, delivered it to the muscle cells and in the eyes of mice via adeno-associated viruses and used it to modify a gene causing blindness.

21 Feb 2017

Neonatal sepsis risk calculator reduces antibiotic use by nearly 50% in newborns

Kaiser Permanente, the largest integrated health system in the nation, led the development of a neonatal sepsis risk calculator that has safely reduced antibiotic use by nearly 50 percent in newborns, according to research published today in JAMA Pediatrics.

21 Feb 2017

New class of antibiotics effective in treating children with MRSA skin infections

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial scourge. As its name suggests, MRSA is resistant to most common antibiotics and thus difficult to treat, particularly in children where it commonly causes complicated skin and skin structure infections.

17 Feb 2017

HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

Researchers provide new data and prospects for links between gut microbiota and depression

An international group of researchers headed by André Carvalho has published in Psychotherapy and Psychosomatic a paper that provides new data and prospects for the links between the intestinal flora and several disorders, notably depression.

16 Feb 2017

Study: Physicians more likely to prescribe antibiotics when patients' expectations are high

Experimental evidence confirms what surveys have long suggested: Physicians are more likely to prescribe antibiotics when they believe there is a high expectation of it from their patients, even if they think the probability of bacterial infection is low and antibiotics would not be effective, according to a study published by the American Psychological Association.

16 Feb 2017

Scientists develop new bioinformatics tool to make biological experiments more transparent

Biological experiments are generating increasingly large and complex sets of data. This has made it difficult to reproduce experiments at other research laboratories in order to confirm - or refute - the results.

15 Feb 2017

Researchers discover sulfide-responsive protein that regulates photosynthesis in purple bacteria

Recent evidence demonstrates that the origins of photosynthesis can be found in deep sea hydrothermal vents, where microbes evolved to obtain energy from ejected hydrogen sulfide and methane gases.

15 Feb 2017

Bacterial News and Research

MIT researchers develop new machine to rapidly produce customized peptides

Diagnosing Infections Through Molecules in Patient Breath

New study finds huge problem of multi-drug resistant infections among children

Researchers chart pathway of multidrug resistant bacteria living in hospital sink drainpipes

Structure of unique amyloid fibrils could lead to discovery of new antibiotics

UC San Diego researchers suggest transplanting good bacteria to treat patients with atopic dermatitis

New research pinpoints how immigrant microbes get to the lungs

Duke Health scientists identify proteins in mucous that confirm viral infection

Study describes how bacteria can remodel gene expression to infect intestines of host

First breath of newborn shapes lifelong immunological milieu of lungs

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

Scientists identify novel mutations in bacteria that promote evolution of antibiotic resistance

Scientists engineer smallest CRISPR-Cas9 system to date

Neonatal sepsis risk calculator reduces antibiotic use by nearly 50% in newborns

New class of antibiotics effective in treating children with MRSA skin infections

HMS scientists listen to crosstalk between gut microbes and immune system

Researchers provide new data and prospects for links between gut microbiota and depression

Study: Physicians more likely to prescribe antibiotics when patients' expectations are high

Scientists develop new bioinformatics tool to make biological experiments more transparent

Researchers discover sulfide-responsive protein that regulates photosynthesis in purple bacteria

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