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Genetic mutation found to improve cognitive flexibility in mice

Researchers at the National Institutes of Health have discovered in mice what they believe is the first known genetic mutation to improve cognitive flexibility--the ability to adapt to changing situations.

27 Mar 2020

Heart and kidney patients should keep taking their medicines during COVID-19 pandemic

As the COVID-19 pandemic unfolds, inaccurate medical information has flooded social media and other channels.

27 Mar 2020

New approach shows promise as a treatment for chemo-resistant ovarian cancer

Researchers have made a discovery about the behavior of ovarian cancer cells that could lead to a new treatment approach.

27 Mar 2020

Experimental heart disease drug may treat chemo-resistant ovarian cancer

Most ovarian cancer starts in fallopian tubes. Then it sloughs from its site of origin and floats around in fluid until finding new sites of attachment. It's not easy for cancer cells to survive away from their moorings.

26 Mar 2020

Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

What happens when COVID-19 and cardiovascular diseases mix?

The world has been brought to a stand-still by the COVID-19 pandemic that has affected 197 countries, areas and territories, infected 467,594, and killed 21,181 individuals as of today. COVID-19 disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a single-stranded RNA virus, contagious in humans.

25 Mar 2020

Targeting critical enzyme for sperm formation could help address male infertility

While some of our body's cells divide in a matter of hours, the process of making sperm, meiosis, alone takes about 14 days from start to finish. And fully six of those days are spent in the stage known as the pachytene, when pairs of chromosomes from an individual's mother and father align and connect.

25 Mar 2020

A genetic toolkit to produce multifunctional magnetic nanoparticles

Magnetic bacteria might soon be used for the production of novel biomaterials. A team of microbiologists at the University of Bayreuth led by Prof. Dr. Dirk Schüler developed a modular system for the genetic reprogramming of bacteria, thereby turning the organisms into cell factories for multifunctional magnetic nanoparticles that combine various useful functions and properties.

25 Mar 2020

Changes in surface sugarlike molecules help cancer cells to spread

Changes in a specific type of sugarlike molecule, or glycan, on the surface of cancer cells help them to spread into other tissues, according to researchers at the University of California, Davis. Published March 23 in Proceedings of the National Academy of Sciences, the work could lead to diagnostic tests and new therapies to slow or stop the spread of cancers.

25 Mar 2020

Researchers propose a stopgap measure to help Covid-19 patients in respiratory distress

Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress.

24 Mar 2020

Clinical trial launched to investigate safety and efficacy of antiviral drug for COVID-19

Physician-scientists at four University of California Health medical centers -- UC San Diego Health, UC San Francisco, UC Irvine Health and UC Davis Health -- have begun recruiting participants for a Phase II clinical trial to investigate the safety and efficacy of treating adult patients with COVID-19 with remdesivir, an antiviral drug that has shown activity in animal models and human clinical trials of SARS-CoV, MERS-CoV, Ebola, Marburg and other viruses.

24 Mar 2020

Study: Bacterial protein fragment instigates lung tissue death in pulmonary fibrosis

A bacterial protein fragment instigates lung tissue death in pulmonary fibrosis, a mysterious disease affecting millions of people worldwide, according to a new study from researchers at the University of Illinois at Urbana-Champaign and Mie University in Japan.

24 Mar 2020

Huge WHO trial of COVID-19 therapies begins

As the world reels from the devastating impact and the looming threat of the novel coronavirus COVID-19, researchers around the globe are racing to find a cure that will reduce symptom severity and reverse the course of the disease, freeing up more hospital space and making it possible to treat more of the severely affected cases.

24 Mar 2020

Patients treated with ACEIs and ARBs may be at increased risk of severe COVID-19

James Diaz, MD, MHA, MPH & TM, Dr PH, Professor and Head of Environmental Health Sciences at LSU Health New Orleans School of Public Health, has proposed a possible explanation for the severe lung complications being seen in some people diagnosed with COVID-19.

23 Mar 2020

Researcher working to measure gene expression in blood of patients treated for opioid use disorder

MingKuan Lin, Research Assistant Professor, INOVA Neuroscience, School of Systems Biology, is working to measure gene expression levels in blood from patients undergoing treatment with buprenorphine for opioid use disorder.

22 Mar 2020

Researchers decode 3D architecture of SARS-CoV-2 main protease

Teams around the world are working hard to develop active substances against SARS-CoV-2. The structural analysis of functional proteins of the virus is very helpful for this goal. The function of a protein is closely related to its 3D architecture.

21 Mar 2020

Genetically modified neurons could enhance function of clinical implants

A team has genetically reprogrammed neurons that could enhance electrical implant function used in various clinical scenarios.

20 Mar 2020

World’s fastest supercomputer identifies chemicals with potential to stop COVID-19

What makes the coronavirus disease (COVID-19) global pandemic different from the Spanish flu in 1918? In 1918, transportation, technology, and science were in their infancy, with the medical field not capable of fighting outbreaks. Technology has come a long way, within days, scientists have already identified the type of virus spreading in China, and three months after, vaccine trials have started.

20 Mar 2020

Ibuprofen could increase risk of coronavirus complications

The UK’s National Health Service says that people who have COVID-19 and are self-quarantined should rest and drink plenty of fluids. So far, so good. However, it goes on to advise that they take paracetamol or ibuprofen to keep down fever and pain.

17 Mar 2020

High iron levels in lung increase severity of asthma

A new study published in the European Respiratory Journal in March 2020 reports that the accumulation of iron in the cells of the lung exacerbates asthma symptoms and reduces lung function.

17 Mar 2020

Enzyme News and Research

Genetic mutation found to improve cognitive flexibility in mice

Heart and kidney patients should keep taking their medicines during COVID-19 pandemic

New approach shows promise as a treatment for chemo-resistant ovarian cancer

Experimental heart disease drug may treat chemo-resistant ovarian cancer

Finding new treatments for muscular dystrophy with CRISPR-Cas9

What happens when COVID-19 and cardiovascular diseases mix?

Targeting critical enzyme for sperm formation could help address male infertility

A genetic toolkit to produce multifunctional magnetic nanoparticles

Changes in surface sugarlike molecules help cancer cells to spread

Researchers propose a stopgap measure to help Covid-19 patients in respiratory distress

Clinical trial launched to investigate safety and efficacy of antiviral drug for COVID-19

Study: Bacterial protein fragment instigates lung tissue death in pulmonary fibrosis

Huge WHO trial of COVID-19 therapies begins

Patients treated with ACEIs and ARBs may be at increased risk of severe COVID-19

Researcher working to measure gene expression in blood of patients treated for opioid use disorder

Researchers decode 3D architecture of SARS-CoV-2 main protease

Genetically modified neurons could enhance function of clinical implants

World’s fastest supercomputer identifies chemicals with potential to stop COVID-19

Ibuprofen could increase risk of coronavirus complications

High iron levels in lung increase severity of asthma

Measuring Drug-Target Residence Times with Biochemical Assays eBook

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