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New review highlights several opportunities for improving ginsenoside production

Ginseng, a widely popular superfood, has long been used in traditional medicine. The health benefits of ginseng are largely attributed to compounds called ginsenosides, which are present in the roots, stems, and leaves of the plant. Ginsenosides are known to prevent inflammation, diabetes, and cancer, and can also help control blood cholesterol levels and reduce aging.

16 Sep 2021

Research paves the way for advances in the treatment of many brain disorders

Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.

16 Sep 2021

COVID-19 and the gut-lung axis

A new study explores the hypothesis that stimulation of the gut could be responsible for the lung inflammation seen in COVID-19, triggered by SARS-CoV-2.

16 Sep 2021

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection typically affects children only mildly, multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS) is a serious but rare complication occurring after infection.

16 Sep 2021

Therapeutic potential of clinical-grade ACE2 for blocking SARS-CoV-2 variants

According to new research by an international team of scientists, all SARS-CoV-2 variants, including variants of concern (VOC) Alpha, Beta, Gamma, and Delta, exhibit enhanced affinity toward recombinant human soluble ACE2.

16 Sep 2021

Evolved SARS-CoV-2 viruses gain higher infectivity and cause more rapid infection spread

Viruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strains that show attenuated virulence. Such strains may act as vaccines if the attenuated virus can produce immunity without serious disease.

16 Sep 2021

This 3D modeling reveals how SARS-CoV-2 attacks

Now, researchers at the Garvan Institute of Medical Research, Darlinghurst in Australia, CSIRO Data61, and the School of Biotechnology and Biomolecular Sciences (UNSW) demonstrated the most comprehensive analysis of the three-dimensional structure of SARS-CoV-2, providing a new insight into how the virus infects cells and replicates.

16 Sep 2021

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provide an accurate framework to match patients with non-small cell lung cancer (NSCLC) to the right drugs.

16 Sep 2021

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Researchers in the United States and Germany have conducted a study showing that the Pfizer-BioNTech vaccine designed to protect against coronavirus disease 2019 (COVID-19) is effective against recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2).

16 Sep 2021

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

A recent study published in Tropical Biomedicine determines whether flavonoids can help prevent diarrhea caused by SARS-CoV-2 infection.

15 Sep 2021

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Researchers from Simon Fraser University in Canada decided to investigate the magnitude of immunity in mRNA vaccines for COVID-19.

15 Sep 2021

SARS-CoV-2 variants show substantial differences in spike structure

To investigate the impact of these mutations, researchers performed cryo-electron microscopy analysis on the variants spike proteins to determine any structural changes.

15 Sep 2021

Natural SARS-CoV-2 infection induces more durable immunity than vaccination study suggests

Scientists from the USA have demonstrated that immunity induced by mRNA-based COVID-19 vaccines in previously SARS-CoV-2-infected people has the highest robustness and durability with cross-reactivity against different viral variants.

15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

Flu shots and COVID-19 immunity

A new paper finds that the influenza vaccine may influence both the response to and incidence of infection by the SARS-CoV-2.

14 Sep 2021

Prior symptomatic COVID-19 enhances mRNA vaccine response

A new paper describes the antibody responses in people who have already been infected with SARS-CoV-2 and are vaccinated as compared to the naïve.

14 Sep 2021

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.

14 Sep 2021

Blood serum test can identify which breast cancer patients have slow-growing disease

Researchers with the SWOG Cancer Research Network have found that patients with metastatic hormone receptor-positive breast cancer who have low activity levels of the enzyme sTK1 in their blood serum at the start of anti-estrogen treatment live longer and go longer without their disease progressing than patients with high levels.

14 Sep 2021

Severe COVID-19 linked to increase in autoantibodies

Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies - antibodies directed at their own tissues or at substances their immune cells secrete into the blood - than people without COVID-19, according to a new study.

14 Sep 2021

New slow-release system mimics nature to provide long-lasting local anesthesia

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties.

14 Sep 2021

Receptor News and Research

New review highlights several opportunities for improving ginsenoside production

Research paves the way for advances in the treatment of many brain disorders

COVID-19 and the gut-lung axis

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

Therapeutic potential of clinical-grade ACE2 for blocking SARS-CoV-2 variants

Evolved SARS-CoV-2 viruses gain higher infectivity and cause more rapid infection spread

This 3D modeling reveals how SARS-CoV-2 attacks

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

SARS-CoV-2 variants show substantial differences in spike structure

Natural SARS-CoV-2 infection induces more durable immunity than vaccination study suggests

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

Flu shots and COVID-19 immunity

Prior symptomatic COVID-19 enhances mRNA vaccine response

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

Blood serum test can identify which breast cancer patients have slow-growing disease

Severe COVID-19 linked to increase in autoantibodies

New slow-release system mimics nature to provide long-lasting local anesthesia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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