Brain Tumor News and Research

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A Brain Tumor is the growth of abnormal cells in the tissues of the brain. Brain tumors can be benign (not cancer) or malignant (cancer).

New finding could become glioblastoma’s Achilles heel

Glioblastoma is the most frequent and aggressive brain cancer due to its ability to escape the immune system. However, the way in which this tumor manages to induce this immune tolerance was not known in detail.

23 Sep 2019

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.

23 Sep 2019

Leukemia drug appears to be effective in treating deadly pediatric brain tumor

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional team led by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego.

21 Sep 2019

Whole-brain radiotherapy recommended for patients with brain metastases

Patients with brain metastases who received whole-brain radiotherapy that avoided memory-specific hippocampal neural stem cells experienced preserved cognitive function and reported fewer neurologic symptoms and better cognition over time, according to results from an NRG Oncology clinical trial presented Sept. 15, 2019 at the American Society for Radiation Oncology Annual Meeting in Chicago.

20 Sep 2019

Brain tumors hijack healthy neurons in order to grow

Scientists have discovered that brain tumors integrate themselves with the brain’s healthy neuronal network to support their growth.

19 Sep 2019

New biomarkers help predict response to treatment in common brain tumor

Many scientists have noted that there is a link between inflammation or the immune response, and patient survival. One such possible relationship is the association of blood markers and the prognosis in the brain tumor called medulloblastoma.

16 Sep 2019

Scientists identify molecule that plays key role in determining fate of cells under stress

St. Jude Children's Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum.

12 Sep 2019

Researchers develop new model to optimize radiation therapy of brain tumors

Researchers have developed a new model to optimize radiation therapy and significantly increase the number of tumour cells killed during treatment.

4 Sep 2019

A factor that predicts prolonged survival in brain tumor uncovered

The discoveries in the cellular and molecular biology of cancer, the development of drugs against specific genetic mutations, and the emergence of immunotherapy are allowing the cure or improvement of the quality of life and life expectancy of patients with tumors.

3 Sep 2019

Cracking the code of a recurrent brain cancer

One of the most common brain cancers in children, Sonic Hedgehog (SHH) medulloblastoma, also is one of the more survivable for most kids. Unfortunately, for a subset of patients the cancer resists treatment and relapses with a vengeance to then turn deadly.

30 Aug 2019

Study opens up a new way for developing potential glioblastoma treatment

A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of cancer.

22 Aug 2019

Research explains why many psychiatric drugs that work in the lab don’t work in people

Current drug development for neuropsychiatric disorders is in crisis, say experts. More than 90 percent of all drugs that are developed for illnesses like schizophrenia, depression, Alzheimer’s disease (AD), or the brain tumor glioblastoma complete successful trials in mice but then come to a grinding halt in human trials, wasting billions of dollars in drug research. This is partly because of obvious behavioral differences between the two species.

22 Aug 2019

International study identifies new drug target for treating glioblastoma

A new international study co-led by Cleveland Clinic has identified a new drug target for treating glioblastoma. This target is part of a never-before defined cellular pathway found to contribute to the spread and proliferation of a dangerous subset of cancer cells, called glioma stem cells.

22 Aug 2019

Simple test could help diagnose glioblastoma

Scientists at the University of Sussex could be a step closer to developing the first-ever blood test to diagnose the most aggressive type of brain cancer, glioblastoma.

20 Aug 2019

Treatment with both targeted cancer therapy and MS drug halts glioblastoma stem cells

Glioblastoma is an aggressive form of brain cancer that infiltrates surrounding brain tissue, making it extremely difficult to treat with surgery.

9 Aug 2019

New breast cancer drug identified as a potential therapy for glioblastoma

The Ivy Brain Tumor Center at the Barrow Neurological Institute, has released the results of its recent Phase 0 clinical trial of the breast cancer drug ribociclib (Kisqali) for the treatment of recurrent glioblastoma.

25 Jul 2019

Researchers turn to single-cell analysis to understand a pediatric brain tumor

Investigators at St. Jude Children's Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric brain tumor.

25 Jul 2019

Chemotherapy drugs delivered using biodegradable paste can prolong survival in brain cancer

A combination of chemotherapy drugs during brain cancer surgery using a biodegradable paste, leads to long-term survival, researchers at the University of Nottingham have discovered.

18 Jul 2019

Repurposing a heart drug could increase survival rate of children with ependymoma

Researchers at the University of Nottingham have discovered that repurposing a heart drug could significantly increase the survival rate for children with ependymoma - a type of brain tumor.

16 Jul 2019

Researchers identify potential drug target for multiple cancer types

A research team headed by scientists at University of California San Diego School of Medicine and the Ludwig Institute for Cancer Research at UC San Diego has identified an enzyme involved in remodeling the plasma membrane of multiple cancer cell types that is critical to both survival of tumors and their uncontrolled growth.

11 Jul 2019