Craniofacial News and Research

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Research yields potential target for cancer, wound healing and fibrosis

Research conducted by Allison Berrier, PhD, Assistant Professor of Oral and Craniofacial Biology at the LSU Health Sciences Center New Orleans School of Dentistry, and colleagues, provides insights that may help scientists design novel approaches to control wound healing and fight diseases such as cancer and fibrosis.

20 Mar 2009

Risk factors for flat head syndrome

A new study by physician researchers from Hasbro Children's Hospital and Children's Hospital Boston identifies risk factors for the severity of asymmetrical head shapes, known as deformational plagiocephaly (DP), or more commonly as flat head syndrome.

11 Mar 2009

New study finds increased prevalence of left-handedness in children with facial development disorder

A new study by physician researchers from Hasbro Children's Hospital and Children's Hospital Boston has identified an increased prevalence in left-handedness in children with a congenital disorder known as hemifacial microsomia (HFM).

2 Mar 2009

Why do teeth form in a single row?

A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published in the journal Science.

26 Feb 2009

Lack of specific gene plays role in autism

It is estimated that three to six out of every 1,000 children in the United States have autism - and the number of diagnosed cases is rising.

9 Feb 2009

Missing gene plays role in autism

It is estimated that three to six out of every 1,000 children in the United States have autism - and the number of diagnosed cases is rising.

8 Feb 2009

Safer optic nerve decompression surgery

Knowing about variations in the location of the optic nerve and ophthalmic artery can aid surgeons in performing optic nerve decompression - a delicate operation performed in patients with vision loss resulting from head injury, reports a study in the November Journal of Craniofacial Surgery.

21 Dec 2008

Botulinum toxin used to treat patients with masseteric muscle hypertrophy

For patients with an uncommon condition causing a swollen appearance of the lower face, treatment with botulinum toxin type A (Botox) provides an effective alternative to plastic surgery, according to a study in the November Journal of Craniofacial Surgery.

21 Dec 2008

Dental pulp stem cells show promise for use in cell therapy

Researchers at the Yerkes National Primate Research Center, Emory University, have discovered dental pulp stem cells can stimulate growth and generation of several types of neural cells.

12 Nov 2008

New advances in diagnosis and treatment of allergic diseases

Researchers are presenting more than 450 abstracts on investigational findings in the diagnosis and treatment of allergic diseases at the ACAAI Annual Meeting in Seattle, Nov. 6-11. Following are highlights of some key studies in allergy-immunology.

11 Nov 2008

Researchers discover genetic basis for some common congenital birth defects

10 Nov 2008

Absence of ERK2 gene linked to birth defects

A multidisciplinary research team at Case Western Reserve University led by Gary Landreth, Ph.D., a professor in the School of Medicine's Department of Neurosciences, has uncovered a common genetic pathway for a number of birth defects that affect the development of the heart and head. Abnormal development of the jaw, palate, brain and heart are relatively common congenital defects and frequently arise due to genetic errors that affect a key developmental pathway.

10 Nov 2008

Scientist says research indicates need for effective HPV vaccine for women and men and a simple HPV screening test

A call to explore a broader use of HPV (human papillomavirus) vaccines and the validation of a simple oral screening test for HPV-caused oral cancers are reported in two studies by a Johns Hopkins Kimmel Cancer Center investigator.

3 Nov 2008

Researchers discover how Sonic hedgehog gene controls brain development

University of Pennsylvania School of Medicine researchers have discovered how the expression of the Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause brain malformations. The results appear online this month in Nature Genetics.

28 Oct 2008

Discovery of gene variant for cleft lip

About 20 percent of isolated cleft lip, one of the world's most common birth defects, may be due to a one-letter difference in the DNA sequence of a gene involved in facial development, researchers supported by the National Institutes of Health report.

6 Oct 2008

Scientists develop ultra-sensitive optical protein sensor, a first for a salivary diagnostic test

For people who dislike needles, medical tests that require a drop of saliva instead of a vial of blood will one day make a trip to a doctor or dentist much easier. But as scientists now construct the first of these saliva tests for early signs of cancer and other diseases, they continue to push the technological envelope in interesting ways.

3 Aug 2008

Binge drinking in pregnancy increases risk of oral clefts in offspring

A new study by researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, shows that pregnant women who binge drink early in their pregnancy increase the likelihood that their babies will be born with oral clefts.

31 Jul 2008

Lost viruses may contribute to AIDS

Weak HIV viruses piggyback onto stronger ones, raising the possibility that the human body may harbor many more HIV viruses capable of replicating and contributing to the development of AIDS than previously thought, according to research published in BioMed Central's open access journal, Retrovirology.

8 Jul 2008

Palatal surgery in less lexically advanced, younger children associated with better speech outcomes

A new study published in The Cleft Palate-Craniofacial Journal has found that the timing of palatal surgery and size of lexicon, or vocabulary, in children are important factors to consider in determining the most beneficial management of children with cleft palate.

15 May 2008

Plastic surgeons to develop groundbreaking therapies for war injury research

Members of the American Society of Plastic Surgeons (ASPS) will play a pivotal role over the next five years developing groundbreaking therapies to better treat U.S. soldiers critically injured in Iraq and Afghanistan.

17 Apr 2008