Developmental Biology News and Research

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Multimodal mapping of immune landscape in pancreatic cancer could guide personalized therapies

Pancreatic cancer has remained resistant to immunotherapies that are revolutionizing the treatment of many types of cancer.

27 Oct 2020

Study finds new transposon-derived genes related to autism

The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona, and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide.

27 Oct 2020

3D whole-heart imaging technique provides new insights on congenital heart disease

A cutting-edge technique that allows scientists to zoom into tiny details in a 3D image of a whole animal heart may lead to new insights on congenital heart disease.

20 Oct 2020

New lab test for detection of SARS-CoV-2 antibodies gives results more quickly than existing assays

Knowing you have developed antibodies against the SARS-CoV-2 virus after recovering from COVID-19 doesn't tell you everything about your immunity.

19 Oct 2020

Researchers report the discovery of innate immune signaling pathway in fibroblasts

Vanderbilt University researchers have reported the counterintuitive discovery that certain chemotherapeutic agents used to treat tumors can have the opposite effect of tissue overgrowth in normal, intact mammary glands, epidermis and hair follicles.

16 Oct 2020

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Why are some people more resilient to viruses than others? The answer has eluded scientists for centuries and, in the age of COVID-19, has come to represent one of the holy grails of biomedical research.

16 Oct 2020

New technology precisely diagnoses sickle cell disease in a minute

Researchers at the University of Colorado Boulder and the University of Colorado Anschutz Medical Campus have developed a new way to diagnose diseases of the blood like sickle cell disease with sensitivity and precision and in only one minute.

15 Oct 2020

Molecular mechanisms play key role in the development of healthy heart

It might look like a little game at the molecular scale.Filament-like proteins in heart muscle cells have to be exactly the same length so that they can coordinate perfectly to make the heart beat.

14 Oct 2020

Cell-free DNA blood tests may help predict pregnancy complications

UCLA researchers say a blood test commonly used to detect fetal genetic abnormalities may help predict complications associated with pregnancy before symptoms develop.

13 Oct 2020

New quality control system in protein production assembly can shed light on neurogenerative disease

Recent work led by Carnegie's Kamena Kostova revealed a new quality control system in the protein production assembly line with possible implications for understanding neurogenerative disease.

9 Oct 2020

Simple interactions between nerve cells can shape complex brain circuits

Complex brain circuits in rodents can organize themselves with genetics playing only a secondary role, according to a new computer modelling study published today in eLife.

30 Sep 2020

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology.

30 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Gruthan Bioscience, LLC, a Medical University of South Carolina startup based in Charleston, South Carolina, received a Small Business technology Transfer (STTR) award from the National Heart, Blood and Lung Institute in August to take the next step in developing a novel class of cholesterol-lowering drugs to treat familial hypercholesterolemia.

24 Sep 2020

Study identifies a gene's previously unknown role in fertility

A new study from Washington University School of Medicine in St. Louis identifies a specific gene's previously unknown role in fertility.

31 Aug 2020

Study shows how medicine can benefit from dinosaur research

Researchers from the University of Bonn: Even Tyrannosaurus rex could have suffered a slipped disc. The intervertebral discs connect the vertebrae and give the spine its mobility.

24 Aug 2020

A new mechanism by which microtubule networks instruct neuronal polarity revealed

Prof. MENG Wenxiang's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences recently reported a new mechanism by which microtubule networks instruct neuronal polarity.

21 Aug 2020

Scientists create miniature human heart model in the lab

A team of researchers from Michigan State University has created a miniature human heart model in the laboratory. For the first time in history, this mode is complete with all primary heart cell types and a functioning structure of chambers and vascular tissue.

19 Aug 2020

Gene variants help explain link between skin condition and food allergies

Two common variants in the KIF3A gene increase the risk of young children having a dysfunctional skin barrier and developing the skin condition atopic dermatitis.

14 Aug 2020

Research identifies a potential therapeutic target for clogged arteries

New work led by Carnegie's Meredith Wilson and Steve Farber identifies a potential therapeutic target for clogged arteries and other health risks that stem from an excess of harmful fats in the bloodstream. Their findings are published by PLOS Genetics.

7 Aug 2020