Gene Editing News and Research

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Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Unusual partners are key to making more blood vessels

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

8 Mar 2022

Study reveals new insights on how immune system cells respond to disease-causing pathogens

In laboratory experiments involving a class of mutations in people with a rare collection of immune system disorders, Johns Hopkins Medicine researchers say they have uncovered new details about how immune system cells respond to disease-causing bacteria, fungi and viruses such as SARS-CoV-2.

8 Mar 2022

Current and future perspectives of mRNA technology

New research reports on the current and future perspectives on messenger ribonucleic acid technology, the platform on which the first successful COVID-19 vaccine was based.

8 Mar 2022

Targeting a specific protein can help prevent or delay prostate cancer progression

Targeting a specific protein that is often overexpressed in prostate cancer can help prevent or delay the disease from spreading to other parts of the body, according to a study led by Cedars-Sinai Cancer investigators.

25 Feb 2022

Crucial regulator of malaria parasite transmission identified

Malaria remains one of the biggest global public health challenges. It kills a young child every two minutes, more than any other infectious disease.

25 Feb 2022

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Researchers at NTNU have managed to restore muscle function in older mice with muscle loss using advanced gene therapy. The hope is that this method might eventually be used on humans to prevent severe loss of muscle mass.

24 Feb 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers at the Tufts University School of Engineering are building a reputation for precision targeting in drug delivery.

23 Feb 2022

New open-source software tool could accelerate genetic discoveries

Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation should accelerate their development - as well as genetic editing advances overall.

17 Feb 2022

Transformational $104 million gift will help VCU to expand treatment options for liver diseases

Virginia Commonwealth University will radically expand treatment options for liver and liver-related metabolic diseases thanks to a historic, transformational $104 million gift from Richard Todd Stravitz, M.D., and his family's Barbara Brunckhorst Foundation.

15 Feb 2022

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

While the word "mutation" may conjure up alarming notions, a mutation in brain immune cells serves a positive role in protecting people against Alzheimer's disease.

14 Feb 2022

Scientists introduce a genetic mutation to provide protection against Alzheimer's disease

Researchers from the Université Laval Faculty of Medicine and CHU de Québec–Université Laval Research Centre have successfully edited the genome of human cells grown in vitro to introduce a mutation providing protection against Alzheimer's disease.

10 Feb 2022

Defective mitochondrial DNA could be modified using gene-editing techniques

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

8 Feb 2022

CRISPRa method helps discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

3 Feb 2022

Combined treatment strategy essential to minimize lung sequelae in COVID-19 patients

A combined treatment strategy targeting SARS-CoV-2 symptoms and severe lung tissue injury is essential to minimize lung sequelae- chronic complications resulting from COVID-19 infection, according to a review published this week in Clinical Microbiology Reviews, a journal of the American Society for Microbiology.

2 Feb 2022

New report investigates how genomics could play a part in our lives in the future

A new wide-ranging report Genomics Beyond Health published today by the Government Office for Science investigates how genomics could play a part in our lives in the future, from sport to education and tackling crime.

25 Jan 2022

How artificial intelligence is poised to reshape medicine

In a recent review published in the journal of Nature Medicine, researchers discussed the results of a two-year weekly effort to track and communicate significant developments in medical (artificial intelligence) AI. They included prospective studies as well as developments in medical image analysis that have narrowed the gap between research and implementation.

24 Jan 2022

Scientists develop new drug delivery system for treating genetic diseases

A team of researchers led by Harvard and Broad Institute scientists has developed a new drug delivery system using engineered DNA-free virus-like particles (eVLPs) to package and deliver therapeutic levels of gene-editing proteins to animal models of disease.

22 Jan 2022

UAB research outlines successful xenotransplantation of genetically modified kidneys

The University of Alabama at Birmingham Marnix E. Heersink School of Medicine announces today the first peer-reviewed research outlining the successful transplant of genetically modified, clinical-grade pig kidneys into a brain-dead human individual, replacing the recipient's native kidneys.

20 Jan 2022

Gene Editing News and Research

Using mRNA to introduce gene editor into human muscle stem cells

Unusual partners are key to making more blood vessels

Study reveals new insights on how immune system cells respond to disease-causing pathogens

Current and future perspectives of mRNA technology

Targeting a specific protein can help prevent or delay prostate cancer progression

Crucial regulator of malaria parasite transmission identified

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

New open-source software tool could accelerate genetic discoveries

Transformational $104 million gift will help VCU to expand treatment options for liver diseases

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

Scientists introduce a genetic mutation to provide protection against Alzheimer's disease

Defective mitochondrial DNA could be modified using gene-editing techniques

CRISPRa method helps discover genes that play a role in immune cell biology

Combined treatment strategy essential to minimize lung sequelae in COVID-19 patients

New report investigates how genomics could play a part in our lives in the future

How artificial intelligence is poised to reshape medicine

Scientists develop new drug delivery system for treating genetic diseases

UAB research outlines successful xenotransplantation of genetically modified kidneys

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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