Glycated hemoglobin News and Research

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Linagliptin safe and effective for African American patients with type 2 diabetes

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announced Phase 3 study results for linagliptin 5 mg once-daily, which showed significant hemoglobin A1c (HbA1c or A1C) reduction of 0.88 percent compared to 0.24 percent in the placebo group (p=0.0002) at 24 weeks in black or African American adult patients with type 2 diabetes whose blood sugar was not adequately controlled.

25 May 2012

Severity of nocturnal hypoxemia and SDB independently predict both T2DM and HbA1c levels

The severity of sleep disordered breathing and nocturnal hypoxemia independently predict both glycosylated hemoglobin (HbA1c) levels and type 2 diabetes mellitus (T2DM), according to a new study.

24 May 2012

Hygieia’s DIGS automatically adjusts insulin dosage in patients with diabetes

Newly published results from a clinical study of the Diabetes Insulin Guidance System (DIGS-), under development by Hygieia, Inc., demonstrate DIGS' potential to improve blood glucose control for insulin-using patients with type 2 or type 1 diabetes. DIGS automatically adjusted insulin dosage based on each individual's reported blood glucose results.

10 May 2012

Bariatric surgery effectively controls diabetes

Overweight, diabetic patients who underwent bariatric surgery achieved significant improvement or remission of their diabetes, according to new research from Cleveland Clinic.

27 Mar 2012

Bariatric surgery better than standard medical treatment for severe type 2 diabetes

In the first published study of its kind, researchers from the Catholic University/Policlinico Gemelli in Rome, Italy, and NewYork-Presbyterian/Weill Cornell Medical Center found that bariatric surgery dramatically outperforms standard medical treatment of severe type 2 diabetes.

27 Mar 2012

Research roundup: Unequal 'culture of quality' in hospitals; Peer-support for stressed doctors

Comparison Of Hospital Performance In Trauma Vs Emergency And Elective General Surgery –This study compared outcomes of trauma patients and patients having either elective or emergency surgery in the same hospital. Researchers thought that "hospital performance reflected institutional culture, and, thus, would be similar across all services."

23 Mar 2012

Peer mentor intervention improves glucose control in African American veterans with diabetes

by peer mentors has a statistically significant effect on improving glucose control in African American veterans with diabetes, according to a study by researchers at the Perelman School of Medicine at the University of Pennsylvania and the Philadelphia VA Center for Health Equity Research and Promotion.

20 Mar 2012

Soy-based S-equol lowers HbA1c, LDL cholesterol and improves vascular stiffness

A 12-week treatment of the fermented soy germ-based nutritional supplement containing S-equol significantly lowered hemoglobin A1c (HbA1c), LDL cholesterol and improved vascular stiffness, all factors that occur as part of metabolic syndrome, according to a first-of-its-kind peer-reviewed study reported in a poster at the Women's Health 2012 annual meeting.

19 Mar 2012

Experts highlight latest advances in use of biomarkers in various diseases

Over the last few decades there has been an explosion in the discovery of biomarkers for diagnosis, disease monitoring, and prognostic evaluation. In the April issue of Translational Research, entitled "Biomarkers: New Tools of Modern Medicine," an international group of medical experts explores the promise and challenges of biomarker discovery and highlights the latest advances in the use of biomarkers in various diseases.

16 Mar 2012

H. pylori bacteria associated with elevated levels of HbA1c

A new study by researchers at NYU Langone Medical Center reveals that the presence of Helicobacter pylori (H. pylori) bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes.

15 Mar 2012

Lowering HbA1c cutoffs increases health benefits of type 2 diabetes preventive interventions

The American Diabetes Association recommends hemoglobin A1c (HbA1c) testing as one basis for identifying diabetes and prediabetes.

13 Mar 2012

TAK-875 as effective as glimepiride in treating type 2 diabetes

TAK-875, a new treatment for type 2 diabetes, improves blood sugar control and is equally effective as glimepiride, but has a significantly lower risk of creating a dangerous drop in blood sugar, called hypoglycemia, according to a new study.

27 Feb 2012

New drug improves glycaemic control with minimum risk of hypoglycemia in type 2 diabetics

27 Feb 2012

The Lancet publishes Takeda's TAK-875 Phase 2 data on type 2 diabetes

Phase 2 clinical data of an investigational type 2 diabetes therapy, TAK-875 of Takeda Pharmaceutical Company Limited, were published online first in The Lancet.

27 Feb 2012

Chronic hyperglycemia may lead to cardiac damage

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests that hyperglycemia (high blood sugar) injures the heart, even in patients without a history of heart disease or diabetes.

3 Feb 2012

Blood sugar self-monitoring has no benefit for diabetics not on insulin

For type 2 diabetics who are not on insulin, monitoring their blood sugar does little to control blood sugar levels over time and may not be worth the effort or expense, according to a new evidence review.

30 Jan 2012

Study: Electronic health records can improve care, outcomes in patients with type 2 diabetes

Use of electronic health records shows promise for improving care and outcomes in patients with type 2 diabetes, but still has considerable room for improvement, according to a new study in the journal Health Services Research.

30 Jan 2012

Diabetes may cause women to experience hearing loss as they age

Having diabetes may cause women to experience a greater degree of hearing loss as they age, especially if the metabolic disorder is not well controlled with medication, according to a new study from Henry Ford Hospital in Detroit.

27 Jan 2012

New biomarkers can predict risk of kidney failure in patients with diabetes

Scientists at Joslin Diabetes Center have identified two novel markers that, when elevated in the blood stream, can predict accurately the risk of renal (kidney) failure in patients with Type 1 and Type 2 diabetes.

20 Jan 2012

Progress report on commercialization of BENLYSTA to be announced at JPMorgan Healthcare Conference

Human Genome Sciences, Inc. will today announce its priority goals for 2012 and report on progress with the commercialization of BENLYSTA (belimumab), the first approved drug for systemic lupus in 56 years, during a presentation this afternoon by H. Thomas Watkins, President and Chief Executive Officer, to financial analysts and investors at the 30th Annual JPMorgan Healthcare Conference in San Francisco.

9 Jan 2012

Glycated hemoglobin News and Research

Linagliptin safe and effective for African American patients with type 2 diabetes

Severity of nocturnal hypoxemia and SDB independently predict both T2DM and HbA1c levels

Hygieia’s DIGS automatically adjusts insulin dosage in patients with diabetes

Bariatric surgery effectively controls diabetes

Bariatric surgery better than standard medical treatment for severe type 2 diabetes

Research roundup: Unequal 'culture of quality' in hospitals; Peer-support for stressed doctors

Peer mentor intervention improves glucose control in African American veterans with diabetes

Soy-based S-equol lowers HbA1c, LDL cholesterol and improves vascular stiffness

Experts highlight latest advances in use of biomarkers in various diseases

H. pylori bacteria associated with elevated levels of HbA1c

Lowering HbA1c cutoffs increases health benefits of type 2 diabetes preventive interventions

TAK-875 as effective as glimepiride in treating type 2 diabetes

New drug improves glycaemic control with minimum risk of hypoglycemia in type 2 diabetics

The Lancet publishes Takeda's TAK-875 Phase 2 data on type 2 diabetes

Chronic hyperglycemia may lead to cardiac damage

Blood sugar self-monitoring has no benefit for diabetics not on insulin

Study: Electronic health records can improve care, outcomes in patients with type 2 diabetes

Diabetes may cause women to experience hearing loss as they age

New biomarkers can predict risk of kidney failure in patients with diabetes

Progress report on commercialization of BENLYSTA to be announced at JPMorgan Healthcare Conference

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