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Direct comparison of immune memory responses to four COVID-19 vaccines

Researchers evaluated host immune responses to four COVID-19 vaccines representing three different vaccine technology platforms, focusing on immune memory responses.

30 May 2022

Hemodialysis patients obtain a robust humoral response from a third dose of the BNT162b2 vaccine, study finds

Researchers assessed the humoral immune responses generated by the third Pfizer-BioNTech BNT162b2 mRNA vaccination against SARS-CoV-2 among hemodialysis patients.

30 May 2022

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Researchers compared the polymer-nanoparticle hydrogel system and standard routes of delivery of broadly neutralizing antibodies against SARS-CoV-2 in a mouse model.

27 May 2022

Study assesses the safety of breastfeeding during maternal SARS-CoV-2 infection

Researchers assessed the presence of anti-SARS-CoV-2 antibodies in human breast milk.

26 May 2022

Mucosal COVID vaccine candidate powerfully protective in macaques

A recent research paper posted to the bioRxiv* preprint server illustrated the protective efficacy of the intranasal pediatric parainfluenza virus-vectored coronavirus disease 2019 (COVID-19) vaccine prospect, B/HPIV3/S-6P, in macaques.

26 May 2022

Study shows glomerulonephritis after SARS-CoV-2 mRNA vaccination likely coincidental

In a recent study posted to the medRxiv* pre-print server, researchers assessed whether messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines increase the incidence of glomerulonephritis against the null hypothesis stating any observed temporal association between the two phenomena was purely coincidental.

26 May 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

Study illustrates risk of Omicron infection in fully vaccinated individuals

Scientists studied SARS-CoV-2 humoral responses in a healthy young person who was infected by the Omicron BA.1.15 after receiving booster vaccination.

25 May 2022

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

A recent study currently under review at Scientific Reports journal and posted to the Research Square* preprint server demonstrated a potential positive correlation between reactogenicity and immunogenicity of coronavirus disease 2019 (COVID-19) vaccination.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Anti-SARS-CoV-2 antibodies from breast milk persist in infants’ digestive tract

The current preliminary investigation study published in the journal Nutrients sought to investigate the longevity of anti-SARS-CoV-2 immunoglobulin (Ig)A and IgG in breast milk during the in vitro-simulated gastrointestinal digestion.

24 May 2022

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

The study findings showed that the rapid antigen tests with the DMS approach could accurately identify antibody escape mutations in the SARS-CoV-2 N protein.

24 May 2022

Study reveals the cross-protective role of Omicron infection in vaccinated individuals

A new study compares the cross-protective humoral responses to different SARS-CoV-2 variants induced by vaccination or infection.

23 May 2022

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

Researchers evaluate the persistence of anti-SARS-CoV-2 IgA and IgG in breast milk before and after in vitro gastrointestinal digestion.

23 May 2022

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

A new study investigated whether a specific population of local Bmem cells in the proximal LNs produce secondary GC responses that are different from those at distal sites and if the location in humoral immunity is relevant only to nonlymphoid tissues.

23 May 2022

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Researchers designed an efficient vaccine design against SARS-CoV-2 infections.

23 May 2022

Immunoglobulin News and Research

Direct comparison of immune memory responses to four COVID-19 vaccines

Hemodialysis patients obtain a robust humoral response from a third dose of the BNT162b2 vaccine, study finds

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Study assesses the safety of breastfeeding during maternal SARS-CoV-2 infection

Mucosal COVID vaccine candidate powerfully protective in macaques

Study shows glomerulonephritis after SARS-CoV-2 mRNA vaccination likely coincidental

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

Study illustrates risk of Omicron infection in fully vaccinated individuals

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Anti-SARS-CoV-2 antibodies from breast milk persist in infants’ digestive tract

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

Study reveals the cross-protective role of Omicron infection in vaccinated individuals

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Study shows a strong negative association between BNT162b2 vaccination-induced S1 IgG concentration and age

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Women who are pregnant or nursing should receive a COVID booster vaccination

Anti-SARS-CoV-2 titers predict COVID severity

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