Immunosuppression News and Research

RSS

Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.

Understanding the rise in NTM infections

It is important to keep in mind that nontuberculous mycobacteria are environmental, and so unlike mycobacterial tuberculosis, generally this is not a person to person transmitted disease. The organisms are found universally in water and soil and so most people are exposed on a daily basis.

16 Aug 2017

New review shows potential of Vitamin B3 for preventing melanoma

A new review highlights the potential of nicotinamide (Vitamin B3) for preventing melanoma in high-risk individuals.

9 Aug 2017

New report says completing a course of antibiotics even after symptoms abate is overrated

Antibiotics are a boon to mankind and as more and more microorganisms are developing a resistance to these drugs, researchers are delving deeper into the mechanisms of this resistance. It is a commonly held view that once begun, a course of antibiotics should be completed to prevent the emergence of resistance among the microbes.

26 Jul 2017

Cocktail of drugs for HIV patients with advanced immunosuppression reduced deaths by 27%, study shows

A study published in the New England Journal of Medicine on 20th July 2017 suggests that a cocktail of drugs, if provided at the beginning of the HIV therapy, can save over 10,000 lives per year. HIV, which is often diagnosed late, leaves people vulnerable to other diseases by ravaging the immune system.

25 Jul 2017

Researchers receive $8.6 million NIH grant for efforts to improve lung transplantation

Researchers at the University of Virginia School of Medicine have received more than $8.6 million in federal grants to support efforts that could dramatically increase the number of lungs available for transplant – and then save the lives of the people who receive them.

6 Jul 2017

SCT scientists develop Neo-Islet technology for treating insulin-dependent diabetes

The cover of the July 2017 issue of the journal STEM CELLS Translation Medicine showcases the latest advance toward a functional cure of insulin-dependent diabetes.

30 Jun 2017

Multiparity improves outcomes after stroke in female mice

Stroke is an age-related disease that disproportionately affects women. Although experimental studies have identified several hormonal and genetic factors underlying these differences, little is known about how pregnancy influences risk as this has not been previously studied in the laboratory setting.

28 Jun 2017

Could the mTOR pathway be used to protect against cancer?

The mTOR pathway is probably the main pathway in humans and other animals that drives growth. That is, the accumulation of mass and adding mass to make an organism bigger by both making more cells, and making cells grow and become bigger.

22 Jun 2017

Kidney graft success depends on age, sex of donor and recipient, study reveals

The success of kidney transplant is dependent on the age and sex of both the donor and the recipient, according to research published today in the Journal of the American Society of Nephrology.

8 Jun 2017

New study suggests potential new therapeutic approach to septic shock recovery

A new study published online in the Journal of Leukocyte Biology suggests a new approach to treating patients with sepsis, one of the most frequent causes of morbidity and mortality in intensive care units.

1 Jun 2017

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

In the body, anti-cancer immunity is immobilized by stealth cancer forces. But a natural de-immobilizer has been identified - and it has a vendetta.

12 May 2017

Study: Systemic therapy preserves vision of uveitis patients better than intraocular implant

Systemic therapy consisting of corticosteroids and immunosuppressants preserved vision of uveitis patients better - and had fewer adverse outcomes - than a long-lasting corticosteroid intraocular implant, according to a clinical trial funded by the National Eye Institute.

9 May 2017

Study finds effective treatment approach for preserving long-term vision in patients with severe uveitis

Researchers comparing leading treatment approaches for patients with severe uveitis have discovered that systemic therapy with oral corticosteroids and immunosuppression can preserve or improve vision in the long term better than regional implant therapy can.

8 May 2017

White blood cells play key role in bringing harmful virus under control after kidney transplant

Certain white blood cells play an important role in bringing a harmful virus under control after kidney transplantations. The results of a research group at the Department of Biomedicine at the University of Basel and University Hospital Basel could contribute to improving control of immunosuppression, avoiding transplant rejection and developing relevant vaccines.

30 Mar 2017

World's leading heart failure congress sets new record for abstract submissions

A new record for original science submissions has been set for the world's leading heart failure congress. In addition to the main abstract programme, highly anticipated results from major studies will be presented in the late breaking trial sessions.

29 Mar 2017

Researchers provide better understanding of the body's immune responses to implanted materials

Researchers at MIT and Boston Children's Hospital have published a report today in the journal Nature Materials that provides a better understanding of the body's immune responses to the materials used in implanted medical devices.

22 Mar 2017

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system.

2 Feb 2017

UCLA-led researchers identify potential TB drug regimen that may cut treatment time up to 75%

Taking a new approach toward tuberculosis therapy, a UCLA-led research team has devised a potential drug regimen that could cut the treatment time by up to 75 percent, while simultaneously reducing the risk that patients could develop drug-resistant TB.

25 Jan 2017

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo.