Neurological Disease News and Research

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New study focuses on best, cost effective practices to bridge treatment gap for brain disorders

Up to eight out of ten patients with a brain disorder remain untreated or inadequately treated. But what is the best practice - and above all, most cost effective - healthcare interventions to bridge the treatment gap? This was the focus of the European Brain Council's study entitled The Value of Treatment which was discussed at the Congress of the European Academy of Neurology in Lisbon.

18 Jun 2018

Researchers look for deeper explanations into causes of Alzheimer's disease

For more than 20 years, much of the leading research on Alzheimer's disease has been guided by the "amyloid hypothesis."

7 Jun 2018

Microbiotica collaborates with Genentech to develop drugs for IBD

Microbiotica, a leading player in microbiome-based therapeutics spun out of the Wellcome Sanger Institute, today announced that it has entered into a multi-year strategic collaboration with Genentech, a member of the Roche Group, to discover, develop and commercialize biomarkers, targets and medicines for inflammatory bowel disease.

6 Jun 2018

New brain implant may help treat Parkinson's disease

Deep brain stimulation has been used to treat Parkinson's disease symptoms for 25 years, but limitations have led researchers to look for ways to improve the technique.

30 May 2018

Most concussion patients do not receive follow-up care after hospital discharge, says study

As evidence builds of more long-term effects linked to concussion, a nationwide study led by scientists at UCSF and the University of Southern California has found that more than half of the patients seen at top-level trauma centers may fall off the radar shortly after diagnosis, placing in jeopardy treatments for these long-term effects.

25 May 2018

Drug combination may prevent secondary stroke in certain patients, study shows

Results from an international clinical trial of more than 4880 participants, published in the New England Journal of Medicine, show that combining clopidogrel and aspirin following a small stroke or experiencing minor stroke symptoms decreases risk of a new stroke, heart attack or other ischemic event within 90 days.

17 May 2018

New AI software accurately identifies commonest cause of stroke and dementia

Machine learning has detected one of the commonest causes of dementia and stroke, in the most widely used form of brain scan, more accurately than current methods.

17 May 2018

Study uncovers new circuit that fine tunes brain's decision to hide or confront threats

In a study of mice, National Institutes of Health-funded researchers describe a new circuit involved in fine-tuning the brain's decision either to hide or confront threats.

11 May 2018

Study identifies molecule that may be critical to repair of white matter

A new study identifies a molecule that may be critical to the repair of white matter, the fatty tissue wrapped around parts of brain cells that helps speed up communication. Damage to white matter is associated with several conditions, including multiple sclerosis and cerebral palsy, and can occur in the brains of preterm babies.

7 May 2018

Gene therapy offers potential cure for patients with lipoprotein lipase deficiency

During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the first patient to receive the treatment had no abdominal pain or episodes of pancreatitis, following a history of 37 pancreatitis attacks.

2 May 2018

Functional connectivity MRI could help detect brain disorders and diseases

There are no laboratory tests to diagnose migraines, depression, bipolar disorder and many other ailments of the brain. Doctors typically gauge such illnesses based on self-reported symptoms and behavior.

18 Apr 2018

New research sheds light on how neurons in the brain communicate with one another

Researchers from the University of Leicester have shed new light on how neurons in the brain communicate with one another. This could potentially help in our understanding of how and why a range of neurodegenerative diseases occur.

10 Apr 2018

Researchers find potential remedy that could restore hearing for millions

Researchers at USC and Harvard have developed a new approach to repair cells deep inside the ear -- a potential remedy that could restore hearing for millions of elderly people and others who suffer hearing loss.

5 Apr 2018

Study identifies potential genetic link in sudden infant death syndrome

Rare genetic mutations associated with impairment of the breathing muscles are more common in children who have died from sudden infant death syndrome (also known as ‘cot death’) than in healthy controls, suggesting a possible genetic element of the disorder, according to a case-control study in the UK and USA published in The Lancet.

29 Mar 2018

Researchers uncover cause of rare childhood neurodegenerative disease

Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells.

23 Mar 2018

Specific immune cells may help slow progression of ALS, research shows

New research into Amyotrophic Lateral Sclerosis (ALS) - also known as motor neuron disease - shows that specific immune cells may help slow progression of the disease, an important step towards developing new therapies to treat patients.

22 Mar 2018

Transplanting enhanced interneurons restores brain rhythms in mouse model of Alzheimer’s

Like a great orchestra, your brain relies on the perfect coordination of many elements to function properly. And if one of those elements is out of sync, it affects the entire ensemble. In Alzheimer's disease, for instance, damage to specific neurons can alter brainwave rhythms and cause a loss of cognitive functions.

15 Mar 2018

NIH researchers explore genetic clocks to understand role of aging in neurodegeneration

To understand the link between aging and neurodegenerative disorders such as Alzheimer's disease, NIH scientists compared the genetic clocks that tick during the lives of normal and mutant flies.

14 Mar 2018

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis and frontotemporal dementia caused by mutations in a gene called C9orf72.

13 Mar 2018

Scientists uncover detailed map of the brain circuits behind thirst and satiety

Scientists uncovered a high-resolution map of the wiring inside the mouse brain's thirst center. With these blueprints, they could trick mice into becoming light or heavy water drinkers.

8 Mar 2018