Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Phase 2 clinical trial investigates the effectiveness of innovative procedure to control Type 2 diabetes

More than 37 million Americans have diabetes, and approximately 90-95% have Type 2 diabetes.

16 Mar 2023

Artificial pancreas technology improves blood glucose control in young children with type 1 diabetes

Artificial pancreas technology improved blood glucose control in young children between ages 2 and 5 with type 1 diabetes, according to the results of the Pediatric Artificial Pancreas (PEDAP) Trial, a 13-week randomized controlled trial conducted at three pediatric diabetes centers across the United States.

15 Mar 2023

Vitamin A-rich diet may reduce risk of developing asparaginase-associated pancreatitis in ALL patients

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

15 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

Insulin deficiency leads to reduced pancreas size in type 1 diabetes

Individuals with Type 1 diabetes have a smaller pancreas than people without diabetes. This is surprising because insulin-producing beta cells account for just a small fraction of the pancreas, so the loss of beta cells in Type 1 diabetes would not be expected to reduce pancreas size.

10 Mar 2023

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Research published today shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver).

9 Mar 2023

COVID-19 patients at increased risk of developing gastrointestinal disorders

People who have had COVID-19 are at increased risk of developing gastrointestinal (GI) disorders within a year after infection compared with people who haven't been infected, according to an analysis of federal health data by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

8 Mar 2023

Promising alternative strategy for islet transplantation in people with type 1 diabetes

In people with type 1 diabetes, the body's immune system attacks and destroys insulin-producing β cells that control blood glucose levels and are part of a group of cells in the pancreas called pancreatic islets.

1 Mar 2023

Clinical study reveals new use for high blood pressure drug in pediatric patients

A clinical study conducted by Indiana University School of Medicine researchers revealed that oral verapamil, a readily available and commonly used drug to treat high blood pressure and heart conditions, can also improve the pancreas' insulin secretion in children with newly-diagnosed type 1 diabetes (T1D).

1 Mar 2023

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

1 Mar 2023

Childhood adiposity associated with increased risk of recently proposed subtypes of adult-onset diabetes

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) is the first study to show that childhood obesity is associated with an increased risk of four of the five recently proposed subtypes of adult-onset diabetes.

28 Feb 2023

Weight loss in obese subjects could reverse type 2 diabetes progression

A new paper explains a model of diabetes that centers on the role of obesity in glucose dysregulation.

28 Feb 2023

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

Published in JAMA, a University of Minnesota led study shows that verapamil, a drug commonly used to treat high blood pressure and heart conditions, can have a beneficial effect on the pancreas in children with newly-diagnosed type 1 diabetes (T1D).

24 Feb 2023

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D.

22 Feb 2023

Pancreas News and Research

Further Reading

Phase 2 clinical trial investigates the effectiveness of innovative procedure to control Type 2 diabetes

Artificial pancreas technology improves blood glucose control in young children with type 1 diabetes

Vitamin A-rich diet may reduce risk of developing asparaginase-associated pancreatitis in ALL patients

Embryonic stem cells used to recreate thyroid cancer histotypes

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

Insulin deficiency leads to reduced pancreas size in type 1 diabetes

A small protein could provide a revolutionary approach to tackling obesity-related diseases

COVID-19 patients at increased risk of developing gastrointestinal disorders

Promising alternative strategy for islet transplantation in people with type 1 diabetes

Clinical study reveals new use for high blood pressure drug in pediatric patients

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Childhood adiposity associated with increased risk of recently proposed subtypes of adult-onset diabetes

Weight loss in obese subjects could reverse type 2 diabetes progression

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

Researchers reveal the metabolic reactions upon activating Akt2 enzyme

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

Study provides a rare view of real-world use of off-label drugs prescribed for Type 1 diabetes

Fear and anxiety during the COVID-19 pandemic associated with new alcohol use disorder diagnoses

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

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