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High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

The current study aims to use sophisticated machine learning models that stratify patient data by age group to predict disease progression in almost 7,000 patients studied in community hospital settings.

4 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

Stroke survivors can now reduce their chances of death by 76% through modified cardiac rehabilitation

Survivors of serious stroke can reduce their chances of dying within the year by 76% if they complete a modified cardiac rehabilitation program that includes medically supervised exercise, prescribed therapy, and physician follow-up, according to new research published in the Journal of Stroke & Cerebrovascular Diseases, published by Elsevier. The findings have the potential to change the future of stroke care.

4 May 2022

Study suggests SARS-CoV-2 Omicron is as deadly as past variants

A recent article under review at the Nature Portfolio journal and currently posted to the Research Square* preprint server compared the severity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant with prior mutants.

4 May 2022

Study reveals trends in clinical characteristics and outcomes of STEMI patients with COVID-19

A newly published analysis in the Journal of the American College of Cardiology1 of hospitalized patients with both a severe type of heart attack called STEMI (ST-elevation myocardial infarction) and coronavirus disease-19 (COVID-19) infection compares clinical outcomes for these patients during the first and second years of the COVID-19 pandemic.

3 May 2022

New WHO report recommends interventions and policy options to tackle obesity in Europe

The new WHO European Regional Obesity Report 2022, published on 3 May by the WHO Regional Office for Europe, reveals that overweight and obesity rates have reached epidemic proportions across the Region and are still escalating, with none of the 53 Member States of the Region currently on track to meet the WHO Global Noncommunicable Disease (NCD) target of halting the rise of obesity by 2025.

3 May 2022

Multi-omics identify COVID-19 severity predictors and prothrombotic signatures in patients with end-stage kidney disease

Researchers demonstrated that plasma levels of leucine-rich repeat-containing 15 are a strong indicator of the severity of COVID-19 in patients with end-stage kidney disease.

3 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

Study explores which occupations had the greatest risk of SARS-CoV-2 infection and how relative differences varied over the pandemic

Researchers investigated occupations at the highest risk for SARS-CoV-2 infection.

3 May 2022

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

Glioma is an intracranial malignant tumor that still poses a major clinical challenge due to its highly invasive nature, low cure rate, and high mortality rate.

3 May 2022

Mexico City Policy may be associated with higher maternal, child mortality and HIV incidence rates

Restricting US foreign aid for non-governmental organizations (NGOs) that provide information on or access to abortion-related services in developing countries may have harmful effects on maternal and child mortality and HIV incidence rates on the same scale as an ongoing civil conflict.

2 May 2022

A “less is more” method may prevent antibiotic overuse in pediatric intensive care unit patients

When a patient in the pediatric intensive care unit (PICU) develops a fever, physicians often routinely order a blood culture to identify the cause, particularly if they have reason to worry about sepsis, a life-threatening condition that occurs when chemicals released by immune system cells in the bloodstream to fight an infection trigger inflammation and shock throughout the body.

2 May 2022

Ongoing cancer research mainly focuses on disparities and equity

Years of cancer research continues to yield valuable insight and life-saving measures. The topic of cancer disparities and equity, which aims to understand why some groups of people may be more or less likely to develop cancer, experience cancer-related health problems, or have less frequent use of screening tests than other groups of people, is one of many research areas being explored and critical to progress against the disease.

2 May 2022

Fourth dose of COVID-19 vaccine reduced death among hospitalized patients during Omicron wave in Israel

Study highlights the need to improve clinical management of Malawian children with low blood sugar or blood oxygen levels

A new study in rural Malawi underscores the need for better clinical management of severely ill children with very low blood sugar or blood oxygen levels.

29 Apr 2022

Mortality News and Research

High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

Researchers create models to study brain metastases that recapitulate the disease

Stroke survivors can now reduce their chances of death by 76% through modified cardiac rehabilitation

Study suggests SARS-CoV-2 Omicron is as deadly as past variants

Study reveals trends in clinical characteristics and outcomes of STEMI patients with COVID-19

New WHO report recommends interventions and policy options to tackle obesity in Europe

Multi-omics identify COVID-19 severity predictors and prothrombotic signatures in patients with end-stage kidney disease

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Study explores which occupations had the greatest risk of SARS-CoV-2 infection and how relative differences varied over the pandemic

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

Mexico City Policy may be associated with higher maternal, child mortality and HIV incidence rates

A “less is more” method may prevent antibiotic overuse in pediatric intensive care unit patients

Ongoing cancer research mainly focuses on disparities and equity

Fourth dose of COVID-19 vaccine reduced death among hospitalized patients during Omicron wave in Israel

Higher vaccination coverage associated with lower rates of population-level COVID-19 mortality and incidence in the US

Detailed estimates of cancer incidence, mortality and survival in Canada

How diet and nutrition impacts lifespan

Study explores sex-driven differences in individualized clinical management of Alzheimer’s disease risk

Exploring happy hypoxia in COVID-19 patients

Study highlights the need to improve clinical management of Malawian children with low blood sugar or blood oxygen levels

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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