Genes News and Research

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Research brings us closer to optimizing treatments for children with retinoblastoma

Retinoblastoma is a cancer of the eye that occurs in infants and toddlers and can lead to loss of vision, loss of one or both eyes, and even death.

26 Sep 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.

26 Sep 2022

What is the association between body fat and COVID-19?

Researchers recently assessed the association between adipose tissues and COVID-19 by evaluating autopsy cases and profiling adipose tissue responses to SARS-CoV-2 infections.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

A new study shows that sleep does much more, regulating the normal production of blood cells. This finding underlines how essential a healthy sleep routine is for a normal life.

26 Sep 2022

Coral genome reveals an alternative pathway for cysteine biosynthesis

Model animals, such as mice and fruit flies, have provided scientists with powerful insights into how cellular biology works. However, model animals are really just a guide, and it can be risky to generalize findings across animals from studying a selection of model organisms.

23 Sep 2022

Studies explore how differences in skin composition may lead to dermatological conditions

Why are certain body parts more prone to skin diseases than others? Two new UC Davis Health studies explored how differences in skin composition may lead to dermatological conditions, such as psoriasis and atopic dermatitis.

23 Sep 2022

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

In a new paper, University of California, Irvine researchers explain how precision genome editing agents have enabled precise gene correction and disease rescue in inherited retinal diseases (IRDs).

23 Sep 2022

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown.

23 Sep 2022

Scientists identify the mechanism responsible for exceptional auditory abilities in Williams-Beuren syndrome

Williams-Beuren syndrome (WBS) is a rare disorder that causes neurocognitive and developmental deficits. However, musical and auditory abilities are preserved or even enhanced in WBS patients.

23 Sep 2022

Shape-shifting fat cells offer a fertile soil for breast tumor invasion and growth

Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study by UT Southwestern researchers suggests.

23 Sep 2022

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA.

22 Sep 2022

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC).

22 Sep 2022

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Monon Bioventures LLC has received a one-year, $398,314 Phase I Small Business Innovation Research, or SBIR grant from the National Cancer Institute to demonstrate the feasibility of manufacturing a glioblastoma therapeutic created at the Purdue University College of Pharmacy.

22 Sep 2022

Sarbecovirus discovered in Russian bat can infect humans and is resistant to SARS-CoV-2 vaccines

A recently discovered virus in a Russian bat that is similar to SARS-CoV-2, the virus behind COVID-19, is likely capable of infecting humans and, if it were to spillover, is resistant to current vaccines.

22 Sep 2022

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Two scientists at the David Geffen School of Medicine at UCLA have been awarded nearly $10 million from the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative for research projects that aim to shed light on the developing brain's cellular infrastructure to better understand brain disorders.

22 Sep 2022

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

With a five-year, $126 million grant from the National Institutes of Health, a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas.

22 Sep 2022

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

In a new study, a team of researchers explored the effect of immune checkpoint blockade (ICB)-induced expansion of age-associated B cells (ABCs) on COVID-19 vaccine-derived humoral immunity in patients with cancer and inborn errors of immunity (IEI).

22 Sep 2022

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

The prevalence, age of onset, and clinical symptoms for virtually all neuropsychiatric disorders differ between men and women. Among the disorders with pronounced sex bias are Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), where the ratio of males/females diagnosed is approximately 4 to 1.

21 Sep 2022

Genes News and Research

Research brings us closer to optimizing treatments for children with retinoblastoma

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

What is the association between body fat and COVID-19?

Common germline variants of APOE contribute to differential COVID-19 outcomes

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

Coral genome reveals an alternative pathway for cysteine biosynthesis

Studies explore how differences in skin composition may lead to dermatological conditions

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Scientists identify the mechanism responsible for exceptional auditory abilities in Williams-Beuren syndrome

Shape-shifting fat cells offer a fertile soil for breast tumor invasion and growth

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Sarbecovirus discovered in Russian bat can infect humans and is resistant to SARS-CoV-2 vaccines

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

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