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Early life stress or trauma could rewire the brain for later neuropathological disorders

Federal researchers have discovered that severe stress or trauma early in life could actually change how the brain responds to stress hormones, essentially "re-wiring" the brain for later neuropathological disorders, according to a study, "A role for corticotrophin releasing factor signaling in the lateral habenula and its modulation by early life stress," published in Science Signaling, March 6.

7 Mar 2018

Female mosquito brain map may help uncover neural circuitry behind biting and other behaviors

A mosquito's head is about the size of a pencil tip, but it packs a dangerous punch: it is the delivery system for malaria, yellow fever, and Zika, among other blood-borne diseases. In most mosquito species, females are the more dangerous sex. They're the ones drinking - and transferring - blood.

7 Mar 2018

Individual damaged nerve cells cause neurodegenerative diseases

If the sense of smell disappears, this can indicate a disease such as Alzheimer's or Parkinson's disease. However, unlike previously assumed, general degenerations in the nervous system do not play a leading role in the loss of the sense of smell with increasing age, but individual nerve cells or classes of nerves are decisive.

7 Mar 2018

Duke scientists pinpoint new therapeutic target for macular degeneration

Duke Researchers have pinpointed a new therapeutic target for macular degeneration, an eye disease that affects over 10 million Americans and is the leading cause of blindness in adults over 60.

6 Mar 2018

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

Although certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD remains a mystery.

6 Mar 2018

Study uncovers new target in Parkinson’s disease

A new study has uncovered a relationship between the presence of Lewy bodies and neuronal cell death in Parkinson's disease.

6 Mar 2018

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

Treatments targeted to enhance brain neurotrophic factor signaling could improve memory functions in Alzheimer's disease even though they don't alter brain amyloid burden, according to recent research from the University of Eastern Finland.

6 Mar 2018

TSRI research offers explanation for why neurons die off in Parkinson's disease

An estimated 10 million people worldwide are living with Parkinson's disease--an incurable neurodegenerative disorder that leads to an increasing loss of motor control.

6 Mar 2018

Research shows how interaction between nervous and immune systems occurs in lung infections

When the body is fighting infection, the immune system kicks into high gear. But emerging evidence hints at the involvement of another, rather surprising, player in this process: the nervous system.

5 Mar 2018

Researcher develops new technology for long-term stable neural recording

Klas Tybrandt, principal investigator at the Laboratory of Organic Electronics at Linköping University, has developed new technology for long-term stable neural recording. It is based on a novel elastic material composite, which is biocompatible and retains high electrical conductivity even when stretched to double its original length.

5 Mar 2018

Scientists find algorithm for brain simulations on exascale systems

An international group of researchers has made a decisive step towards creating the technology to achieve simulations of brain-scale networks on future supercomputers of the exascale class.

5 Mar 2018

Study sheds light on neuronal responses in ALS

In a recent study, scientists have linked changes in the size of motor neurons to the onset of symptoms in motor neurone disease (ALS).

5 Mar 2018

Comprehensive computer models accurately capture diversity of neurons

The Allen Institute for Brain Science has produced the first comprehensive, publicly available database of predictive neuron models, along with their corresponding data.

2 Mar 2018

Researchers gain better understanding of anatomically distinct microcircuit brain networks

Roberto Fernández Galán, an assistant professor of electrical engineering and computer science at the university's School of Engineering, and a team of undergraduate researchers at Case Western Reserve have been recording the electrical activity of hundreds of neurons as they fire inside the brain of a mouse model-for up to half an hour at a time.

1 Mar 2018

Caltech scientists map neural circuit that regulates thirst

There are few feelings more satisfying than gulping down water when you are thirsty. But how does your brain know when you are dehydrated or satiated, and how does it use this information to initiate or terminate drinking? Caltech scientists have now mapped the circuit of neurons within the mouse brain that regulates thirst by stimulating and suppressing the drive to drink water.

1 Mar 2018

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

InSysBio continues to investigate the mechanisms underlying Alzheimer's disease using the quantitative systems pharmacology modeling approach. The part of QSP model describing tau protein was published in the PLOS ONE journal. This is one of more than dozen InSysBio publications in AD area during last seven years.

28 Feb 2018

Receptors crucial for establishing strong memories

When we create a memory, a pattern of connections forms between neurons in the brain. New work from UC Davis shows how these connections can be strengthened or weakened at a molecular level. The study is published Feb. 27 in the journal Cell Reports.

27 Feb 2018

Specific genes linked to differences in brain anatomy of autistic children

A team of scientists at the University of Cambridge has discovered that specific genes are linked to individual differences in brain anatomy in autistic children.

27 Feb 2018

UC receives $1.75 million grant for epilepsy research

Research scientist Jianxiong Jiang, PhD, doesn't just want to treat acquired epilepsy...he hopes to prevent it.

27 Feb 2018

Premature birth has selective effect on functional networks of a child's brain

Researchers at the University of Helsinki and the Helsinki University Hospital have proven that premature birth has a significant and, at the same time, a very selective effect on the functional networks of a child's brain. The effects can primarily be seen in the frontal lobe, which is significant for cognitive functions.

26 Feb 2018

Neurons News and Research

Early life stress or trauma could rewire the brain for later neuropathological disorders

Female mosquito brain map may help uncover neural circuitry behind biting and other behaviors

Individual damaged nerve cells cause neurodegenerative diseases

Duke scientists pinpoint new therapeutic target for macular degeneration

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

Study uncovers new target in Parkinson’s disease

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

TSRI research offers explanation for why neurons die off in Parkinson's disease

Research shows how interaction between nervous and immune systems occurs in lung infections

Researcher develops new technology for long-term stable neural recording

Scientists find algorithm for brain simulations on exascale systems

Study sheds light on neuronal responses in ALS

Comprehensive computer models accurately capture diversity of neurons

Researchers gain better understanding of anatomically distinct microcircuit brain networks

Caltech scientists map neural circuit that regulates thirst

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

Receptors crucial for establishing strong memories

Specific genes linked to differences in brain anatomy of autistic children

UC receives $1.75 million grant for epilepsy research

Premature birth has selective effect on functional networks of a child's brain

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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