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Obesity does not significantly impact short-term complications, outcomes after TSA

Patients with obesity undergo a disproportionately higher number of elective orthopaedic surgeries in the U.S. Obesity has been linked to higher costs, complications, infections and revisions in total knee and total hip replacement surgeries. In a new study published in the Journal of Bone and Joint Surgery, researchers looked at the impact of obesity on the costs and outcomes of total shoulder arthroplasty surgery.

8 Nov 2013

Researchers identify enzymes that are crucial for growth of cancers with genetic aberrations in p53

The most frequently mutated gene across all types of cancers is a gene called p53. Unfortunately it has been difficult to directly target this gene with drugs. Now a multi-institutional research team, led by Dr. Lewis Cantley and investigators at Weill Cornell Medical College, has identified a family of enzymes they say is crucial for the growth of cancers that have genetic aberrations in p53.

8 Nov 2013

Aerobic exercise may be superior to resistance exercise for obese teen girls

Obesity has more than doubled in children and tripled in adolescents in the United States in the past 30 years, according to the Centers for Disease Control and Prevention. The growing rate of childhood obesity is a major health concern since overweight and obese youth are at increased risk of developing several diseases once considered reserved for adults. These new pediatric diseases include type-2 diabetes, metabolic syndrome, and non-alcoholic fatty liver disease, a condition in which fat builds up in the liver, potentially impairing its function over time.

8 Nov 2013

Rice U. researchers link von Willebrand factor to heart-valve calcium deposits

Heart valves calcify over time, and Rice University scientists are beginning to understand why. The Rice lab of bioengineer Jane Grande-Allen found through studies of pigs' heart valves that age plays a critical role in the valves' progressive hardening, and the problem may be due to the infiltration of a protein known as von Willebrand factor.

8 Nov 2013

Increased consumption of vegetable protein linked with prolonged survival among kidney disease patients

Increased consumption of vegetable protein was linked with prolonged survival among kidney disease patients in a new a study. The findings will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

8 Nov 2013

Neonatal jaundice linked to pediatric asthma risk

Researchers have found that neonatal hyperbilirubinemia is associated with an increased risk for childhood asthma.

7 Nov 2013

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

Despite high expectations for the commonly used diabetes drug metformin to improve risk factors for heart disease in people without diabetes, few beneficial effects have been found in a randomised trial of patients with established cardiovascular disease, published in The Lancet Diabetes & Endocrinology.

7 Nov 2013

New study could help lead to prevention and treatment of heart failure in diabetics

Researchers from the University of Texas Medical Branch at Galveston have discovered one of the pathogenic components of diabetes in the heart, as published in the Journal of Biological Chemistry.

7 Nov 2013

Parent's use of digital photography shown as effective tool in diagnosis of retinoblastoma

Can parents use digital cameras and smart phones to potentially screen their children for the most common form of pediatric eye cancer? Baylor University and Harvard Medical School researchers believe so.

7 Nov 2013

Population genetic studies may have limited role in schizophrenia

Studying the genetics of people in the general population who have psychotic experiences is unlikely to yield useful information about schizophrenia, say researchers.

6 Nov 2013

New app now in handy pocket format to help ex-drug and alcohol abusers

Ex-drug and alcohol abusers who have completed their treatment need a simple support system and daily motivation. Now they are getting both - in a handy pocket format.

6 Nov 2013

New treatment option for patients with most difficult-to-treat forms of hepatitis C

A novel single-pill combination drug could present a new treatment option for patients with the most difficult-to-treat forms of hepatitis C, according to the results of a Phase 2 trial, published in The Lancet.

6 Nov 2013

State highlights: Calif. hospital chain settles anesthesia billing suit; study shows graduate medical education funding imbalance

A major California hospital chain, Sutter Health, agreed to pay $46 million and disclose more pricing information to consumers to resolve a whistle-blower complaint alleging false and misleading charges for anesthesia. Sutter Health, which runs 24 acute-care hospitals in Northern California, said it reached the settlement Monday just prior to a trial starting this month over the allegations that it added thousands of dollars for "Code 37x" anesthesia charges that were already covered by other billing for the hospital operating room (Terhune, 11/4).

6 Nov 2013

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

New research shows that chronic stress changes gene activity in immune cells before they reach the bloodstream. With these changes, the cells are primed to fight an infection or trauma that doesn't actually exist, leading to an overabundance of the inflammation that is linked to many health problems.

6 Nov 2013

Researchers link species of intestinal bacteria to onset of rheumatoid arthritis

Researchers have linked a species of intestinal bacteria known as Prevotella copri to the onset of rheumatoid arthritis, the first demonstration in humans that the chronic inflammatory joint disease may be mediated in part by specific intestinal bacteria.

6 Nov 2013

Ambulatory BP best for assessing diabetes CV risk

Ambulatory blood pressure monitoring should be used to monitor patients with Type 2 diabetes who have a high risk for developing cardiovascular complications, say researchers.

5 Nov 2013

Metacognitive training complements antipsychotic therapy

Metacognitive training may benefit patients with schizophrenia who only partially respond to antipsychotic treatment, study findings show.

5 Nov 2013

Effective strategy for noninvasive detection of cancer

Molecules that bind and illuminate proteins specific to tumor cells are key to detecting cancer as early as possible. The cyclooxygenase-2 enzyme is just such a protein, as the concentration of COX-2 is greater in cancer cells than in adjacent normal tissues.

5 Nov 2013

State highlights: GOP tries abortion issue to lure Hispanic vote

A selection of health policy stories from Texas, New York, Virginia, Pennsylvania, California and West Virginia.

5 Nov 2013

Biothera announces top-line results from Phase 2b clinical trial in non-small cell lung cancer

Biothera announced today top-line results from its Phase 2b clinical trial in non-small cell lung cancer (NSCLC) that evaluated its immunotherapeutic drug candidate, Imprime PGG®, with cetuximab (Erbitux®), carboplatin and paclitaxel compared with the monoclonal antibody and chemotherapy combination alone.

5 Nov 2013

X linked News and Research

Obesity does not significantly impact short-term complications, outcomes after TSA

Researchers identify enzymes that are crucial for growth of cancers with genetic aberrations in p53

Aerobic exercise may be superior to resistance exercise for obese teen girls

Rice U. researchers link von Willebrand factor to heart-valve calcium deposits

Increased consumption of vegetable protein linked with prolonged survival among kidney disease patients

Neonatal jaundice linked to pediatric asthma risk

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

New study could help lead to prevention and treatment of heart failure in diabetics

Parent's use of digital photography shown as effective tool in diagnosis of retinoblastoma

Population genetic studies may have limited role in schizophrenia

New app now in handy pocket format to help ex-drug and alcohol abusers

New treatment option for patients with most difficult-to-treat forms of hepatitis C

State highlights: Calif. hospital chain settles anesthesia billing suit; study shows graduate medical education funding imbalance

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

Researchers link species of intestinal bacteria to onset of rheumatoid arthritis

Ambulatory BP best for assessing diabetes CV risk

Metacognitive training complements antipsychotic therapy

Effective strategy for noninvasive detection of cancer

State highlights: GOP tries abortion issue to lure Hispanic vote

Biothera announces top-line results from Phase 2b clinical trial in non-small cell lung cancer

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