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Switching what heart cells consume could help them regenerate

Switching what the powerhouses of heart cells consume for energy could help the heart regenerate when cells die, a new study led by UT Southwestern researchers suggests.

23 Feb 2020

Lipid signaling from beta cells linked to inflammatory macrophage polarization

Do the insulin-producing beta cells in the pancreas unwittingly produce a signal that aids their own demise in Type 1 diabetes?

23 Feb 2020

Researchers develop new probe to detect common target of anti-inflammatory drugs

The Chan group at the Beckman Institute for Advanced Science and Technology has recently developed a probe named CoxFluor, which is able to distinguish between Cyclooxygenase-2, an enzyme that plays a major role in driving the progression of cancer, and Cyclooxygenase-1, which is expressed in all cells.

23 Feb 2020

Amino acids from new torula yeast product are more digestible than fish meal by young pigs

Starting weanling pigs off with the right diet can make all the difference for the health and productivity of the animal.

23 Feb 2020

New study expands the knowledge on tumor-suppressor role of HERC proteins

The RAF protein could be a therapeutical target to treat the tumor growth in regulated pathways by the p38 protein, according to a new study published in the journal Scientific Reports by a team of experts of the Faculty of Medicine and Health Sciences of the University of Barcelona and the Bellvitge Institute for Biomedical Research.

20 Feb 2020

Columbia teams receive $2.1 million grant to find potential antiviral drugs for 2019-nCoV

Four research teams at Columbia University will share a $2.1 million grant to mount an aggressive effort to identify potential antiviral drugs and antibodies for use against the new coronavirus, 2019-nCoV.

20 Feb 2020

Researchers design new drug cocktail to kill brain and soft tissue cancers

Researchers at the USC Viterbi School of Engineering have designed a new drug cocktail that kills some types of brain and soft tissue cancers by tricking the cancer cells to behave as if they were starving for their favorite food--glucose.

20 Feb 2020

Scientists discover novel molecular pathway involved in immunotherapy response

Scientists at The Wistar Institute discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence.

20 Feb 2020

Researchers find the potential of opioid drug to help mask fear memory

Anxiety disorders such as phobias and PTSD are fairly common problems in society. One of the prime causes of anxiety disorders is the inability to overcome the fear for certain contexts when they no longer apply.

19 Feb 2020

Statins could reduce ovarian cancer risk, study suggests

A genetic study has found evidence to suggest that women who take statins in the long term could be less likely to develop ovarian cancer, according to new research funded by Cancer Research UK published today (Tuesday 18 February).

18 Feb 2020

Researchers map key atomic structures in measles, mumps, flu and RSV

Northwestern University researchers have, for the first time, determined the 3D atomic structure of a key complex in paramyxoviruses, a family of viruses that includes measles, mumps, human parainfluenza and respiratory syncytial virus.

17 Feb 2020

Generating genomes and encoding new abilities into artificial DNA

A new study to be presented at the American Association for the Advancement of Science (AAAS) in February 2020 will report on the generation of the world’s first artificially created bacterial genome using a digital design algorithm along with the synthesis of DNA building blocks on a large scale. This genome takes form by chemical rather than template-based synthesis. The research is published in the journal Proceedings of the National Academy of Sciences.

16 Feb 2020

Advancing a protein drug in lettuce leaves to treat pulmonary arterial hypertension

In pulmonary arterial hypertension, high blood pressure in the lungs' arteries causes the heart to work extra hard to pump blood to the lungs and around the rest of the body.

16 Feb 2020

Antibiotic resistance poses a growing risk during pandemics

Researchers investigating the drug prescription response to a "superbug" enzyme that renders bacteria resistant to antibiotics are available to discuss why such resistance is posing a growing risk during pandemics such as the current coronavirus.

14 Feb 2020

New study may lead to better treatments for Parkinson's disease

Parkinson's disease is a long-term (chronic) neurological condition that affects around 12,000 people in Ireland and between 7 and 10 million people worldwide. The disease affects the way the brain co-ordinates body movements like walking and talking, but cognitive abilities are also affected.

13 Feb 2020

Study explains how certain mutations can shorten biological clock timing

A new study of molecular interactions central to the functioning of biological clocks explains how certain mutations can shorten clock timing, making some people extreme "morning larks" because their internal clocks operate on a 20-hour cycle instead of being synchronized with the 24-hour cycle of day and night.

13 Feb 2020

New mathematical technique describes the behavior of cellular enzymes

Everything a cell does, from dividing in two to migrating to a different part of the body, is controlled by enzymes that chemically modify other proteins in the cell.

13 Feb 2020

A143T variant of the GLA gene likely to cause late-onset Fabry cardiomyopathy

The A143T variant of the GLA gene is associated with an increased risk of Fabry cardiomyopathy, according to a new study.

13 Feb 2020

To fight Chinese outbreak, doctors deploy drugs targeting HIV, malaria and Ebola

As the scientific community scrambles to find a drug that can effectively treat tens of thousands of patients sickened by a new respiratory virus, they are trying some surprising remedies: medicines targeting known killers like HIV, Ebola and malaria.

13 Feb 2020

Common human gene variant linked to THC reward in adolescent females

A common variation in a human gene that affects the brain's reward processing circuit increases vulnerability to the rewarding effects of the main psychoactive ingredient of cannabis in adolescent females, but not males, according to preclinical research by Weill Cornell Medicine investigators.

12 Feb 2020